{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2017:4SPRVVMBL7HTTJPLGZ2A2RKJEI","short_pith_number":"pith:4SPRVVMB","schema_version":"1.0","canonical_sha256":"e49f1ad5815fcf39a5eb36740d454922370c59f7c71c33cf2e0f4b722b2be311","source":{"kind":"arxiv","id":"1703.00226","version":1},"attestation_state":"computed","paper":{"title":"Population dynamics of immune repertoires","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.PE","authors_text":"Aleksandra M. Walczak, Andreas Mayer, Jonathan Desponds, Thierry Mora","submitted_at":"2017-03-01T10:54:59Z","abstract_excerpt":"The evolution of the adaptive immune system is characterized by changes in the relative abundances of the B- and T-cell clones that make up its repertoires. To fully capture this evolution, we need to describe the complex dynamics of the response to pathogenic and self-antigenic stimulations, as well as the statistics of novel lymphocyte receptors introduced throughout life. Recent experiments, ranging from high-throughput immune repertoire sequencing to quantification of the response to specific antigens, can help us characterize the effective dynamics of the immune response. Here we describe"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1703.00226","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2017-03-01T10:54:59Z","cross_cats_sorted":[],"title_canon_sha256":"5601c3d4f85ba2f2926dc3597227fe0058620a5584db5d5083b42279e07dbe4e","abstract_canon_sha256":"dcbd947e94b46fb62b402ad027256c3e007c8e8db3d3c6a36ff6de7b45a2e8d0"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:49:45.537776Z","signature_b64":"fSWSfn/xgDVA/OVZCosADzf2D5mXChIUcBDVik7HpiRas4+TlJ5cBkY0hmah19Xgq2G8lU9EO6c9BalCSp3gCw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"e49f1ad5815fcf39a5eb36740d454922370c59f7c71c33cf2e0f4b722b2be311","last_reissued_at":"2026-05-18T00:49:45.537001Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:49:45.537001Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Population dynamics of immune repertoires","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.PE","authors_text":"Aleksandra M. Walczak, Andreas Mayer, Jonathan Desponds, Thierry Mora","submitted_at":"2017-03-01T10:54:59Z","abstract_excerpt":"The evolution of the adaptive immune system is characterized by changes in the relative abundances of the B- and T-cell clones that make up its repertoires. To fully capture this evolution, we need to describe the complex dynamics of the response to pathogenic and self-antigenic stimulations, as well as the statistics of novel lymphocyte receptors introduced throughout life. Recent experiments, ranging from high-throughput immune repertoire sequencing to quantification of the response to specific antigens, can help us characterize the effective dynamics of the immune response. Here we describe"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1703.00226","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1703.00226","created_at":"2026-05-18T00:49:45.537132+00:00"},{"alias_kind":"arxiv_version","alias_value":"1703.00226v1","created_at":"2026-05-18T00:49:45.537132+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1703.00226","created_at":"2026-05-18T00:49:45.537132+00:00"},{"alias_kind":"pith_short_12","alias_value":"4SPRVVMBL7HT","created_at":"2026-05-18T12:31:00.734936+00:00"},{"alias_kind":"pith_short_16","alias_value":"4SPRVVMBL7HTTJPL","created_at":"2026-05-18T12:31:00.734936+00:00"},{"alias_kind":"pith_short_8","alias_value":"4SPRVVMB","created_at":"2026-05-18T12:31:00.734936+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/4SPRVVMBL7HTTJPLGZ2A2RKJEI","json":"https://pith.science/pith/4SPRVVMBL7HTTJPLGZ2A2RKJEI.json","graph_json":"https://pith.science/api/pith-number/4SPRVVMBL7HTTJPLGZ2A2RKJEI/graph.json","events_json":"https://pith.science/api/pith-number/4SPRVVMBL7HTTJPLGZ2A2RKJEI/events.json","paper":"https://pith.science/paper/4SPRVVMB"},"agent_actions":{"view_html":"https://pith.science/pith/4SPRVVMBL7HTTJPLGZ2A2RKJEI","download_json":"https://pith.science/pith/4SPRVVMBL7HTTJPLGZ2A2RKJEI.json","view_paper":"https://pith.science/paper/4SPRVVMB","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1703.00226&json=true","fetch_graph":"https://pith.science/api/pith-number/4SPRVVMBL7HTTJPLGZ2A2RKJEI/graph.json","fetch_events":"https://pith.science/api/pith-number/4SPRVVMBL7HTTJPLGZ2A2RKJEI/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/4SPRVVMBL7HTTJPLGZ2A2RKJEI/action/timestamp_anchor","attest_storage":"https://pith.science/pith/4SPRVVMBL7HTTJPLGZ2A2RKJEI/action/storage_attestation","attest_author":"https://pith.science/pith/4SPRVVMBL7HTTJPLGZ2A2RKJEI/action/author_attestation","sign_citation":"https://pith.science/pith/4SPRVVMBL7HTTJPLGZ2A2RKJEI/action/citation_signature","submit_replication":"https://pith.science/pith/4SPRVVMBL7HTTJPLGZ2A2RKJEI/action/replication_record"}},"created_at":"2026-05-18T00:49:45.537132+00:00","updated_at":"2026-05-18T00:49:45.537132+00:00"}