{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2017:54OVWVL5XDVG2XX42KYZG7O73Q","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"6daa0ded8e9e4088a16d075b1335d7d0245b5e532c39b61aac9c6f5cfc11a2ae","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2017-05-26T14:18:39Z","title_canon_sha256":"d0ad84ca1b7f0d028b294530764fa4079ba4e40617e0d6b4f106a6d4d40c9fdb"},"schema_version":"1.0","source":{"id":"1705.09591","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1705.09591","created_at":"2026-05-18T00:43:38Z"},{"alias_kind":"arxiv_version","alias_value":"1705.09591v1","created_at":"2026-05-18T00:43:38Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1705.09591","created_at":"2026-05-18T00:43:38Z"},{"alias_kind":"pith_short_12","alias_value":"54OVWVL5XDVG","created_at":"2026-05-18T12:31:00Z"},{"alias_kind":"pith_short_16","alias_value":"54OVWVL5XDVG2XX4","created_at":"2026-05-18T12:31:00Z"},{"alias_kind":"pith_short_8","alias_value":"54OVWVL5","created_at":"2026-05-18T12:31:00Z"}],"graph_snapshots":[{"event_id":"sha256:cedc29bcd1ddcf9f8c72bd532f0b5aafac9dc331a3d28e0c17197efec956d6ae","target":"graph","created_at":"2026-05-18T00:43:38Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"In genetic epidemiological studies, family history data are collected on relatives of study participants and used to estimate the age-specific risk of disease for individuals who carry a causal mutation. However, a family member's genotype data may not be collected due to the high cost of in-person interview to obtain blood sample or death of a relative. Previously, efficient nonparametric genotype-specific risk estimation in censored mixture data has been proposed without considering covariates. With multiple predictive risk factors available, risk estimation requires a multivariate model to ","authors_text":"Annie J. Lee, Avi Orr-Urtreger, Helen Mejia-Santana, Karen Marder, Nir Giladi, Susan Bressman, Yuanjia Wang","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2017-05-26T14:18:39Z","title":"Estimation of Genetic Risk Function with Covariates in the Presence of Missing Genotypes"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1705.09591","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:c704d77594c35ded606ebda7688f37bccc070eac8d8b7ba770de9c88cc70cc13","target":"record","created_at":"2026-05-18T00:43:38Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"6daa0ded8e9e4088a16d075b1335d7d0245b5e532c39b61aac9c6f5cfc11a2ae","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2017-05-26T14:18:39Z","title_canon_sha256":"d0ad84ca1b7f0d028b294530764fa4079ba4e40617e0d6b4f106a6d4d40c9fdb"},"schema_version":"1.0","source":{"id":"1705.09591","kind":"arxiv","version":1}},"canonical_sha256":"ef1d5b557db8ea6d5efcd2b1937ddfdc0e02145f24e52fbee49d8964f2e01202","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ef1d5b557db8ea6d5efcd2b1937ddfdc0e02145f24e52fbee49d8964f2e01202","first_computed_at":"2026-05-18T00:43:38.292750Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:43:38.292750Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"iW+OOhrcC1510pMZ429EYG3UZdYqnvIxT+UoFi6S6IPXSUhtrB81JUOYnKsM+jbKKaISrcNtZ2COOP8ICeSVBA==","signature_status":"signed_v1","signed_at":"2026-05-18T00:43:38.293270Z","signed_message":"canonical_sha256_bytes"},"source_id":"1705.09591","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:c704d77594c35ded606ebda7688f37bccc070eac8d8b7ba770de9c88cc70cc13","sha256:cedc29bcd1ddcf9f8c72bd532f0b5aafac9dc331a3d28e0c17197efec956d6ae"],"state_sha256":"350c08024c583a7e3460b84fa84d86a793cee41e83e6ca1fb34afe16f6f55a78"}