{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2026:5DWNQWVVKCSQG5UFIC6MX3BURF","short_pith_number":"pith:5DWNQWVV","canonical_record":{"source":{"id":"2608.12914","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-08-13T07:56:19Z","cross_cats_sorted":["physics.bio-ph","physics.chem-ph"],"title_canon_sha256":"0f42f28d80f7a0aad214cd4090da14945e28353ebe6f191e887ff6227c63b92f","abstract_canon_sha256":"3c522cbad06e019027fde05e0092f8340a3e9b619207507b7cc6e275f9362383"},"schema_version":"1.0"},"canonical_sha256":"e8ecd85ab550a503768540bccbec3489525dae143955b7838054df3ab71697cd","source":{"kind":"arxiv","id":"2608.12914","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2608.12914","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"arxiv_version","alias_value":"2608.12914v1","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2608.12914","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"pith_short_12","alias_value":"5DWNQWVVKCSQ","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"pith_short_16","alias_value":"5DWNQWVVKCSQG5UF","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"pith_short_8","alias_value":"5DWNQWVV","created_at":"2026-08-14T00:58:57Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2026:5DWNQWVVKCSQG5UFIC6MX3BURF","target":"record","payload":{"canonical_record":{"source":{"id":"2608.12914","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-08-13T07:56:19Z","cross_cats_sorted":["physics.bio-ph","physics.chem-ph"],"title_canon_sha256":"0f42f28d80f7a0aad214cd4090da14945e28353ebe6f191e887ff6227c63b92f","abstract_canon_sha256":"3c522cbad06e019027fde05e0092f8340a3e9b619207507b7cc6e275f9362383"},"schema_version":"1.0"},"canonical_sha256":"e8ecd85ab550a503768540bccbec3489525dae143955b7838054df3ab71697cd","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-08-14T00:58:57.165341Z","signature_b64":"nPCSWtCAmEp59gjCOjqOEaAk6utShxmeov9KdeLs57sC7+zXWVwr83GqYTITtE6DcBny7sAT6gpXPqak6fwkCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"e8ecd85ab550a503768540bccbec3489525dae143955b7838054df3ab71697cd","last_reissued_at":"2026-08-14T00:58:57.158629Z","signature_status":"signed_v1","first_computed_at":"2026-08-14T00:58:57.158629Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2608.12914","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-08-14T00:58:57Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"jFJepcz1cjhjv2uzs+utVHD45Vo5FOXZjt7CbhuS5BWGatWZlB+bWOov8rRma7sybMrRcGd49nF+FArB/UcRBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-22T01:40:41.199015Z"},"content_sha256":"802ca7749b22d37d472b271772d24e3d829fea9c27ff421a4c74148c5e750bb0","schema_version":"1.0","event_id":"sha256:802ca7749b22d37d472b271772d24e3d829fea9c27ff421a4c74148c5e750bb0"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2026:5DWNQWVVKCSQG5UFIC6MX3BURF","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Local molecular motions encode time-resolved infrared spectra of proteins","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph","physics.chem-ph"],"primary_cat":"cond-mat.soft","authors_text":"Emanuel Dorbath, Gerhard Stock, Peter Hamm","submitted_at":"2026-08-13T07:56:19Z","abstract_excerpt":"Time-resolved infrared spectroscopy probes protein dynamics over timescales spanning more than ten orders of magnitude, yet the molecular motions underlying the observed kinetic signatures have remained elusive. Here we combine transient infrared spectroscopy with nonequilibrium molecular dynamics simulations to establish a direct connection between experimental relaxation times and local structural motions. Studying single-domain allosteric proteins, we find that inter-residue contact distances provide the structural representation that most faithfully reproduces the experimental dynamics. Co"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2608.12914","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2608.12914/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-08-14T00:58:57Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"WHe6V3gJcYauDdxGq21ayzgCP2b9NwiyjK+63C+zmtPLzc5Yz3pXxtBfNakN41UbS0Ny1W3Zi5bJj7uGqvAyDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-22T01:40:41.199525Z"},"content_sha256":"95d414bbf84b720c20b383e16da248ba69cc9aa1df6cff28f47342d110dacdb3","schema_version":"1.0","event_id":"sha256:95d414bbf84b720c20b383e16da248ba69cc9aa1df6cff28f47342d110dacdb3"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/5DWNQWVVKCSQG5UFIC6MX3BURF/bundle.json","state_url":"https://pith.science/pith/5DWNQWVVKCSQG5UFIC6MX3BURF/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/5DWNQWVVKCSQG5UFIC6MX3BURF/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-22T01:40:41Z","links":{"resolver":"https://pith.science/pith/5DWNQWVVKCSQG5UFIC6MX3BURF","bundle":"https://pith.science/pith/5DWNQWVVKCSQG5UFIC6MX3BURF/bundle.json","state":"https://pith.science/pith/5DWNQWVVKCSQG5UFIC6MX3BURF/state.json","well_known_bundle":"https://pith.science/.well-known/pith/5DWNQWVVKCSQG5UFIC6MX3BURF/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2026:5DWNQWVVKCSQG5UFIC6MX3BURF","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"3c522cbad06e019027fde05e0092f8340a3e9b619207507b7cc6e275f9362383","cross_cats_sorted":["physics.bio-ph","physics.chem-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-08-13T07:56:19Z","title_canon_sha256":"0f42f28d80f7a0aad214cd4090da14945e28353ebe6f191e887ff6227c63b92f"},"schema_version":"1.0","source":{"id":"2608.12914","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2608.12914","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"arxiv_version","alias_value":"2608.12914v1","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2608.12914","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"pith_short_12","alias_value":"5DWNQWVVKCSQ","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"pith_short_16","alias_value":"5DWNQWVVKCSQG5UF","created_at":"2026-08-14T00:58:57Z"},{"alias_kind":"pith_short_8","alias_value":"5DWNQWVV","created_at":"2026-08-14T00:58:57Z"}],"graph_snapshots":[{"event_id":"sha256:95d414bbf84b720c20b383e16da248ba69cc9aa1df6cff28f47342d110dacdb3","target":"graph","created_at":"2026-08-14T00:58:57Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2608.12914/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Time-resolved infrared spectroscopy probes protein dynamics over timescales spanning more than ten orders of magnitude, yet the molecular motions underlying the observed kinetic signatures have remained elusive. Here we combine transient infrared spectroscopy with nonequilibrium molecular dynamics simulations to establish a direct connection between experimental relaxation times and local structural motions. Studying single-domain allosteric proteins, we find that inter-residue contact distances provide the structural representation that most faithfully reproduces the experimental dynamics. Co","authors_text":"Emanuel Dorbath, Gerhard Stock, Peter Hamm","cross_cats":["physics.bio-ph","physics.chem-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-08-13T07:56:19Z","title":"Local molecular motions encode time-resolved infrared spectra of proteins"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2608.12914","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:802ca7749b22d37d472b271772d24e3d829fea9c27ff421a4c74148c5e750bb0","target":"record","created_at":"2026-08-14T00:58:57Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"3c522cbad06e019027fde05e0092f8340a3e9b619207507b7cc6e275f9362383","cross_cats_sorted":["physics.bio-ph","physics.chem-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2026-08-13T07:56:19Z","title_canon_sha256":"0f42f28d80f7a0aad214cd4090da14945e28353ebe6f191e887ff6227c63b92f"},"schema_version":"1.0","source":{"id":"2608.12914","kind":"arxiv","version":1}},"canonical_sha256":"e8ecd85ab550a503768540bccbec3489525dae143955b7838054df3ab71697cd","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"e8ecd85ab550a503768540bccbec3489525dae143955b7838054df3ab71697cd","first_computed_at":"2026-08-14T00:58:57.158629Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-08-14T00:58:57.158629Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"nPCSWtCAmEp59gjCOjqOEaAk6utShxmeov9KdeLs57sC7+zXWVwr83GqYTITtE6DcBny7sAT6gpXPqak6fwkCA==","signature_status":"signed_v1","signed_at":"2026-08-14T00:58:57.165341Z","signed_message":"canonical_sha256_bytes"},"source_id":"2608.12914","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:802ca7749b22d37d472b271772d24e3d829fea9c27ff421a4c74148c5e750bb0","sha256:95d414bbf84b720c20b383e16da248ba69cc9aa1df6cff28f47342d110dacdb3"],"state_sha256":"7a7351fd5a5b871e3df91a61ab2dec6b171947abdcf24c885230017b9c6ebec7"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"YFwF2UvyJfArx9bK8Na/2YZ634tySoaUsJ3C8RuwzrGb7rGMRdbIGIh7yiLmzf0sC5g3xv/tTDW0uz7xGzSeDQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-22T01:40:41.205178Z","bundle_sha256":"a63b509e27248095b02cbf266b9f2db330b44f6f90d8128c0cd3c26f9e7a6c31"}}