{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2026:5EEKFFUR5ZWMVU7YY565UEP6SC","short_pith_number":"pith:5EEKFFUR","canonical_record":{"source":{"id":"2607.07543","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2026-07-08T15:42:23Z","cross_cats_sorted":["q-bio.PE","q-bio.QM"],"title_canon_sha256":"d8c45138e60a6bb7d50218c28b78f0b554ce5a77efeea0dac30cafc757e0cf1c","abstract_canon_sha256":"975a7204da7cd71af96622e9774fa0170f8d910f1bdfca87bfce5b5b93563339"},"schema_version":"1.0"},"canonical_sha256":"e908a29691ee6ccad3f8c77dda11fe90929a1629c01731d55b4458a319b7f839","source":{"kind":"arxiv","id":"2607.07543","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2607.07543","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"arxiv_version","alias_value":"2607.07543v1","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2607.07543","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"pith_short_12","alias_value":"5EEKFFUR5ZWM","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"pith_short_16","alias_value":"5EEKFFUR5ZWMVU7Y","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"pith_short_8","alias_value":"5EEKFFUR","created_at":"2026-07-09T01:20:28Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2026:5EEKFFUR5ZWMVU7YY565UEP6SC","target":"record","payload":{"canonical_record":{"source":{"id":"2607.07543","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2026-07-08T15:42:23Z","cross_cats_sorted":["q-bio.PE","q-bio.QM"],"title_canon_sha256":"d8c45138e60a6bb7d50218c28b78f0b554ce5a77efeea0dac30cafc757e0cf1c","abstract_canon_sha256":"975a7204da7cd71af96622e9774fa0170f8d910f1bdfca87bfce5b5b93563339"},"schema_version":"1.0"},"canonical_sha256":"e908a29691ee6ccad3f8c77dda11fe90929a1629c01731d55b4458a319b7f839","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-09T01:20:28.442418Z","signature_b64":"pz3ZzAXNSN8iJwjW8BsuirAK2M0+P/8wciDq1VO9ElGGybaWR3+ZmSGzs1JeGE9WszMdWS82zO0a6VaRlLPoDA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"e908a29691ee6ccad3f8c77dda11fe90929a1629c01731d55b4458a319b7f839","last_reissued_at":"2026-07-09T01:20:28.442033Z","signature_status":"signed_v1","first_computed_at":"2026-07-09T01:20:28.442033Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2607.07543","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-09T01:20:28Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"P0cCZBj/60Af0t3s3XvExNkRgilSGjRUmDt2SjRjO8RW/KGpOXuMdxi3Tn0NF7mVy7dsKmC1wNmGfAP7pipzAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-07T01:02:39.696364Z"},"content_sha256":"6b8f34cb4567b6e823bf4152d418774fe6abf6964056930fe35471414f787d4f","schema_version":"1.0","event_id":"sha256:6b8f34cb4567b6e823bf4152d418774fe6abf6964056930fe35471414f787d4f"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2026:5EEKFFUR5ZWMVU7YY565UEP6SC","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Equivalence testing in pesticide risk assessment -- Evaluation and practical guidance for design, analysis and interpretation","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["q-bio.PE","q-bio.QM"],"primary_cat":"stat.ME","authors_text":"Dimitry Wintermantel, Florian Hartig, Julia Osterman, Magdalena M. Mair","submitted_at":"2026-07-08T15:42:23Z","abstract_excerpt":"Harmful pesticide effects exceeding specific protection goals (SPG) may go undetected in underpowered experimental designs. Regulatory honeybee field studies have consistently failed to reach the statistical power required under European Food Safety Authority (EFSA) guidance, which may have caused approval of high-risk substances. Therefore, EFSA advised a shift from testing the null hypothesis of 'no effect' to equivalence testing. Under this approach, a pesticide is classified as 'low risk' if the null hypothesis that its effect exceeds the SPG can be rejected. For honeybees, the recommended"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2607.07543","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2607.07543/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-09T01:20:28Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"ATdxrv+SVLgUN9DF30NfFiLZ4c+23ZcS0qo04BAhulA89L3ohED8rIhjnh5LV32ZO509liMZcljoZLslY0RHDg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-07T01:02:39.696862Z"},"content_sha256":"ac8e367eea992c3144b05fc5558891d8eaaeff714b7b3f7efaaaae55b36fe646","schema_version":"1.0","event_id":"sha256:ac8e367eea992c3144b05fc5558891d8eaaeff714b7b3f7efaaaae55b36fe646"},{"event_type":"integrity_finding","subject_pith_number":"pith:2026:5EEKFFUR5ZWMVU7YY565UEP6SC","target":"integrity","payload":{"note":"URL 'https://github.com/Dimitry-Wintermantel/equivalence-testing-and-balanced-' returned status 404 (Not Found) at last check.","snippet":null,"arxiv_id":"2607.07543","detector":"external_links","evidence":{"url":"https://github.com/Dimitry-Wintermantel/equivalence-testing-and-balanced-","final_url":"https://github.com/Dimitry-Wintermantel/equivalence-testing-and-balanced-","host_kind":"github","status_code":404,"status_text":"Not Found","verdict_class":"incontrovertible","checked_at_unix":1783618578.3074894},"severity":"critical","ref_index":null,"audited_at":"2026-07-09T17:36:19.674917Z","event_type":"pith.integrity.v1","detected_doi":null,"detector_url":"https://pith.science/pith-integrity-protocol#external_links","external_url":"https://github.com/Dimitry-Wintermantel/equivalence-testing-and-balanced-","finding_type":"dead_code_link","evidence_hash":"8b2a25e54294129ffea37c798cb95be506ccf3162430ef72e28c93644e7dc8cc","paper_version":1,"verdict_class":"incontrovertible","resolved_title":null,"detector_version":"1.0.0","detected_arxiv_id":null,"integrity_event_id":10184,"payload_sha256":"5bb24a635e20b0cd5c04e0a7bd80d29d171c7cace580f243d5c143a6a714ce59","signature_b64":"Ylg0EZYHkPTkLxzPNoZatpanCUnoQeP++muR1oR8mNKQIycwgDmJSmIGg/Ig+R8y91Y9OPyFrISwOt2m55kFCg==","signing_key_id":"pith-v1-2026-05"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-09T17:38:00Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"iNXTtSB6U3oi7eE4yI1jEtAH6rAy5apamV4LF41eCMXUcLuKlkxCVcbwZF3/z+BpHVpjgsDFtEBjVtQk+2FJCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-07T01:02:39.699661Z"},"content_sha256":"7802e71111d6cb60539898205d2ca930a99e6ca4427e41b73fe07a39c5a40cf0","schema_version":"1.0","event_id":"sha256:7802e71111d6cb60539898205d2ca930a99e6ca4427e41b73fe07a39c5a40cf0"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/5EEKFFUR5ZWMVU7YY565UEP6SC/bundle.json","state_url":"https://pith.science/pith/5EEKFFUR5ZWMVU7YY565UEP6SC/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/5EEKFFUR5ZWMVU7YY565UEP6SC/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-07T01:02:39Z","links":{"resolver":"https://pith.science/pith/5EEKFFUR5ZWMVU7YY565UEP6SC","bundle":"https://pith.science/pith/5EEKFFUR5ZWMVU7YY565UEP6SC/bundle.json","state":"https://pith.science/pith/5EEKFFUR5ZWMVU7YY565UEP6SC/state.json","well_known_bundle":"https://pith.science/.well-known/pith/5EEKFFUR5ZWMVU7YY565UEP6SC/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2026:5EEKFFUR5ZWMVU7YY565UEP6SC","merge_version":"pith-open-graph-merge-v1","event_count":3,"valid_event_count":3,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"975a7204da7cd71af96622e9774fa0170f8d910f1bdfca87bfce5b5b93563339","cross_cats_sorted":["q-bio.PE","q-bio.QM"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2026-07-08T15:42:23Z","title_canon_sha256":"d8c45138e60a6bb7d50218c28b78f0b554ce5a77efeea0dac30cafc757e0cf1c"},"schema_version":"1.0","source":{"id":"2607.07543","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2607.07543","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"arxiv_version","alias_value":"2607.07543v1","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2607.07543","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"pith_short_12","alias_value":"5EEKFFUR5ZWM","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"pith_short_16","alias_value":"5EEKFFUR5ZWMVU7Y","created_at":"2026-07-09T01:20:28Z"},{"alias_kind":"pith_short_8","alias_value":"5EEKFFUR","created_at":"2026-07-09T01:20:28Z"}],"graph_snapshots":[{"event_id":"sha256:ac8e367eea992c3144b05fc5558891d8eaaeff714b7b3f7efaaaae55b36fe646","target":"graph","created_at":"2026-07-09T01:20:28Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2607.07543/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Harmful pesticide effects exceeding specific protection goals (SPG) may go undetected in underpowered experimental designs. Regulatory honeybee field studies have consistently failed to reach the statistical power required under European Food Safety Authority (EFSA) guidance, which may have caused approval of high-risk substances. Therefore, EFSA advised a shift from testing the null hypothesis of 'no effect' to equivalence testing. Under this approach, a pesticide is classified as 'low risk' if the null hypothesis that its effect exceeds the SPG can be rejected. For honeybees, the recommended","authors_text":"Dimitry Wintermantel, Florian Hartig, Julia Osterman, Magdalena M. Mair","cross_cats":["q-bio.PE","q-bio.QM"],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2026-07-08T15:42:23Z","title":"Equivalence testing in pesticide risk assessment -- Evaluation and practical guidance for design, analysis and interpretation"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2607.07543","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:6b8f34cb4567b6e823bf4152d418774fe6abf6964056930fe35471414f787d4f","target":"record","created_at":"2026-07-09T01:20:28Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"975a7204da7cd71af96622e9774fa0170f8d910f1bdfca87bfce5b5b93563339","cross_cats_sorted":["q-bio.PE","q-bio.QM"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2026-07-08T15:42:23Z","title_canon_sha256":"d8c45138e60a6bb7d50218c28b78f0b554ce5a77efeea0dac30cafc757e0cf1c"},"schema_version":"1.0","source":{"id":"2607.07543","kind":"arxiv","version":1}},"canonical_sha256":"e908a29691ee6ccad3f8c77dda11fe90929a1629c01731d55b4458a319b7f839","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"e908a29691ee6ccad3f8c77dda11fe90929a1629c01731d55b4458a319b7f839","first_computed_at":"2026-07-09T01:20:28.442033Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-09T01:20:28.442033Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"pz3ZzAXNSN8iJwjW8BsuirAK2M0+P/8wciDq1VO9ElGGybaWR3+ZmSGzs1JeGE9WszMdWS82zO0a6VaRlLPoDA==","signature_status":"signed_v1","signed_at":"2026-07-09T01:20:28.442418Z","signed_message":"canonical_sha256_bytes"},"source_id":"2607.07543","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:6b8f34cb4567b6e823bf4152d418774fe6abf6964056930fe35471414f787d4f","sha256:ac8e367eea992c3144b05fc5558891d8eaaeff714b7b3f7efaaaae55b36fe646","sha256:7802e71111d6cb60539898205d2ca930a99e6ca4427e41b73fe07a39c5a40cf0"],"state_sha256":"ed684cd216b3b7c652777cecc808162bca1349ded0bf0d0cb5cfa4f358856651"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"A5WnhXTCOO038FYxtpxZTsyjdUnQ23OtFNqo4wXL6kFdaORt8uPHHpwKEC9XRpCipGG/3MVZCNkXsMCPa3RUCA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-07T01:02:39.701810Z","bundle_sha256":"5e138e20d0edd35e646564b13ec9651e662527c94130070633077515ef1fd3b3"}}