{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2025:5ISK3EI6FJG47VVD6JGZR7JZ6M","short_pith_number":"pith:5ISK3EI6","canonical_record":{"source":{"id":"2502.06492","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2025-02-10T14:09:05Z","cross_cats_sorted":[],"title_canon_sha256":"4e44aafc09399dd416caa7cb4b2e989cb6c46446e9d56edf39797cc576383798","abstract_canon_sha256":"37d31eb851213355f86c659ef40a578e89c284f672bb93dd55fe530298b0c89c"},"schema_version":"1.0"},"canonical_sha256":"ea24ad911e2a4dcfd6a3f24d98fd39f302427160482e17d1f39732aa03e7c49e","source":{"kind":"arxiv","id":"2502.06492","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2502.06492","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"arxiv_version","alias_value":"2502.06492v1","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2502.06492","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"pith_short_12","alias_value":"5ISK3EI6FJG4","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"pith_short_16","alias_value":"5ISK3EI6FJG47VVD","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"pith_short_8","alias_value":"5ISK3EI6","created_at":"2026-07-05T10:16:20Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2025:5ISK3EI6FJG47VVD6JGZR7JZ6M","target":"record","payload":{"canonical_record":{"source":{"id":"2502.06492","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2025-02-10T14:09:05Z","cross_cats_sorted":[],"title_canon_sha256":"4e44aafc09399dd416caa7cb4b2e989cb6c46446e9d56edf39797cc576383798","abstract_canon_sha256":"37d31eb851213355f86c659ef40a578e89c284f672bb93dd55fe530298b0c89c"},"schema_version":"1.0"},"canonical_sha256":"ea24ad911e2a4dcfd6a3f24d98fd39f302427160482e17d1f39732aa03e7c49e","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T10:16:20.607072Z","signature_b64":"QtfS7YMJAIgKbMPxnQj5Z9wgDRSD//Hnab/UPod6Nunoxt8Uq2uP358O2E/UpSKnoUf/Fl0n7CSDWqiklgjvCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"ea24ad911e2a4dcfd6a3f24d98fd39f302427160482e17d1f39732aa03e7c49e","last_reissued_at":"2026-07-05T10:16:20.606539Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T10:16:20.606539Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2502.06492","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T10:16:20Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"wSOqINjxlhtM6Kwg0cCuUNLwf0XfKJ9Q8Utq8pg/SZs8L2+ywp2SrXc33Es1hfm/2rPV7lNsGSrW4xuYgS51CA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-08T04:34:54.996928Z"},"content_sha256":"a83edbde635c59df8cc2bc8f3b3e8873579de279e036090073eac6a50a8de34b","schema_version":"1.0","event_id":"sha256:a83edbde635c59df8cc2bc8f3b3e8873579de279e036090073eac6a50a8de34b"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2025:5ISK3EI6FJG47VVD6JGZR7JZ6M","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"An Overview and Recent Developments in the Analysis of Multistate Processes","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"stat.ME","authors_text":"Hein Putter, Maja Pohar Perme, Malka Gorfine, Michal Abrahamowicz (On Behalf of Topic Group 8 \"Survival Analysis\" of the STRATOS Initiative), Per Kragh Andersen, Pierre Joly, Richard J. Cook, Terry M. Therneau","submitted_at":"2025-02-10T14:09:05Z","abstract_excerpt":"Multistate models offer a powerful framework for studying disease processes and can be used to formulate intensity-based and more descriptive marginal regression models. They also represent a natural foundation for the construction of joint models for disease processes and dynamic marker processes, as well as joint models incorporating random censoring and intermittent observation times. This article reviews the ways multistate models can be formed and fitted to life history data. Recent work on pseudo-values and the incorporation of random effects to model dependence on the process history an"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2502.06492","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2502.06492/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T10:16:20Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"CUV387e6TlTdsE2WNaEEUktbLzCUB7AFzGaTmIzrutP7M8KzfnCodirfbuqq5TUsiqa0qflfhQ8HDkxAzlLkAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-08T04:34:54.997302Z"},"content_sha256":"eda9cd790e942ed32d64365f079850898fd6cc9f0491e29e6e9d4e2d1af8fb12","schema_version":"1.0","event_id":"sha256:eda9cd790e942ed32d64365f079850898fd6cc9f0491e29e6e9d4e2d1af8fb12"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/5ISK3EI6FJG47VVD6JGZR7JZ6M/bundle.json","state_url":"https://pith.science/pith/5ISK3EI6FJG47VVD6JGZR7JZ6M/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/5ISK3EI6FJG47VVD6JGZR7JZ6M/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-08T04:34:54Z","links":{"resolver":"https://pith.science/pith/5ISK3EI6FJG47VVD6JGZR7JZ6M","bundle":"https://pith.science/pith/5ISK3EI6FJG47VVD6JGZR7JZ6M/bundle.json","state":"https://pith.science/pith/5ISK3EI6FJG47VVD6JGZR7JZ6M/state.json","well_known_bundle":"https://pith.science/.well-known/pith/5ISK3EI6FJG47VVD6JGZR7JZ6M/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2025:5ISK3EI6FJG47VVD6JGZR7JZ6M","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"37d31eb851213355f86c659ef40a578e89c284f672bb93dd55fe530298b0c89c","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2025-02-10T14:09:05Z","title_canon_sha256":"4e44aafc09399dd416caa7cb4b2e989cb6c46446e9d56edf39797cc576383798"},"schema_version":"1.0","source":{"id":"2502.06492","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2502.06492","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"arxiv_version","alias_value":"2502.06492v1","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2502.06492","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"pith_short_12","alias_value":"5ISK3EI6FJG4","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"pith_short_16","alias_value":"5ISK3EI6FJG47VVD","created_at":"2026-07-05T10:16:20Z"},{"alias_kind":"pith_short_8","alias_value":"5ISK3EI6","created_at":"2026-07-05T10:16:20Z"}],"graph_snapshots":[{"event_id":"sha256:eda9cd790e942ed32d64365f079850898fd6cc9f0491e29e6e9d4e2d1af8fb12","target":"graph","created_at":"2026-07-05T10:16:20Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2502.06492/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Multistate models offer a powerful framework for studying disease processes and can be used to formulate intensity-based and more descriptive marginal regression models. They also represent a natural foundation for the construction of joint models for disease processes and dynamic marker processes, as well as joint models incorporating random censoring and intermittent observation times. This article reviews the ways multistate models can be formed and fitted to life history data. Recent work on pseudo-values and the incorporation of random effects to model dependence on the process history an","authors_text":"Hein Putter, Maja Pohar Perme, Malka Gorfine, Michal Abrahamowicz (On Behalf of Topic Group 8 \"Survival Analysis\" of the STRATOS Initiative), Per Kragh Andersen, Pierre Joly, Richard J. Cook, Terry M. Therneau","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2025-02-10T14:09:05Z","title":"An Overview and Recent Developments in the Analysis of Multistate Processes"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2502.06492","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:a83edbde635c59df8cc2bc8f3b3e8873579de279e036090073eac6a50a8de34b","target":"record","created_at":"2026-07-05T10:16:20Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"37d31eb851213355f86c659ef40a578e89c284f672bb93dd55fe530298b0c89c","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"stat.ME","submitted_at":"2025-02-10T14:09:05Z","title_canon_sha256":"4e44aafc09399dd416caa7cb4b2e989cb6c46446e9d56edf39797cc576383798"},"schema_version":"1.0","source":{"id":"2502.06492","kind":"arxiv","version":1}},"canonical_sha256":"ea24ad911e2a4dcfd6a3f24d98fd39f302427160482e17d1f39732aa03e7c49e","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ea24ad911e2a4dcfd6a3f24d98fd39f302427160482e17d1f39732aa03e7c49e","first_computed_at":"2026-07-05T10:16:20.606539Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T10:16:20.606539Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"QtfS7YMJAIgKbMPxnQj5Z9wgDRSD//Hnab/UPod6Nunoxt8Uq2uP358O2E/UpSKnoUf/Fl0n7CSDWqiklgjvCA==","signature_status":"signed_v1","signed_at":"2026-07-05T10:16:20.607072Z","signed_message":"canonical_sha256_bytes"},"source_id":"2502.06492","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:a83edbde635c59df8cc2bc8f3b3e8873579de279e036090073eac6a50a8de34b","sha256:eda9cd790e942ed32d64365f079850898fd6cc9f0491e29e6e9d4e2d1af8fb12"],"state_sha256":"5f8acc4159db18dd15e12d8f5285f9e836eb636c9231e7547b60e0267ff953a7"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"51HVSFDB8b9pK+G+1EqoXgBDGcYB24uDWbF9GWNMf7GhSZHOF/7cadYkRInoKXH/0m+de+CAVcRCjl+/DFb/Dw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-08T04:34:54.999374Z","bundle_sha256":"4b864a1fb3640fcfd6482d71fe5bd82d3ae5296175335ff6a74365ce04ecfaa3"}}