{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2024:5L34KCATIYIR6NDFQPCEG6MGXM","short_pith_number":"pith:5L34KCAT","canonical_record":{"source":{"id":"2406.09989","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.NC","submitted_at":"2024-06-14T12:54:12Z","cross_cats_sorted":["cs.SY","eess.SY"],"title_canon_sha256":"4db1bd58ec4accc0b101215da3f138eed0394b406a9ea1559f01edbb75d16e87","abstract_canon_sha256":"42e1b4b5e898d76973cad78a440daa9e1ba1807af28a57d309d4e12b9fc20522"},"schema_version":"1.0"},"canonical_sha256":"eaf7c5081346111f346583c4437986bb0caf02c15966d3502f5d4ae1f7e2cb14","source":{"kind":"arxiv","id":"2406.09989","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2406.09989","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"arxiv_version","alias_value":"2406.09989v1","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2406.09989","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"pith_short_12","alias_value":"5L34KCATIYIR","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"pith_short_16","alias_value":"5L34KCATIYIR6NDF","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"pith_short_8","alias_value":"5L34KCAT","created_at":"2026-07-05T08:32:02Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2024:5L34KCATIYIR6NDFQPCEG6MGXM","target":"record","payload":{"canonical_record":{"source":{"id":"2406.09989","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.NC","submitted_at":"2024-06-14T12:54:12Z","cross_cats_sorted":["cs.SY","eess.SY"],"title_canon_sha256":"4db1bd58ec4accc0b101215da3f138eed0394b406a9ea1559f01edbb75d16e87","abstract_canon_sha256":"42e1b4b5e898d76973cad78a440daa9e1ba1807af28a57d309d4e12b9fc20522"},"schema_version":"1.0"},"canonical_sha256":"eaf7c5081346111f346583c4437986bb0caf02c15966d3502f5d4ae1f7e2cb14","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T08:32:02.898100Z","signature_b64":"L5jRhtZWenQb6G+9sW8KVBxm4zPDKv2Ga3PD0C0FIBqJRyA69yom2QZIZzdVduNFbcv5xKXgh+QUq3ELKM5YBw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"eaf7c5081346111f346583c4437986bb0caf02c15966d3502f5d4ae1f7e2cb14","last_reissued_at":"2026-07-05T08:32:02.897602Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T08:32:02.897602Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2406.09989","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T08:32:02Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"+yZ24B9G6GMi3hbghfm884UBXEEqirIHCmihS+ekwbpvAcMpYU1W7aUC1K6DOCeaHK1oYT/mSS9zxBgj2n6KDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-07T13:25:53.534343Z"},"content_sha256":"355b3460159c515e8d4ccd95e03ab63726b2f9c35b0924e79f268fcf7d551973","schema_version":"1.0","event_id":"sha256:355b3460159c515e8d4ccd95e03ab63726b2f9c35b0924e79f268fcf7d551973"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2024:5L34KCATIYIR6NDFQPCEG6MGXM","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Suppressing seizure via optimal electrical stimulation to the hub of epileptic brain network","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":["cs.SY","eess.SY"],"primary_cat":"q-bio.NC","authors_text":"Guanyi Zhao, Jialin Wang, Jingzhe Lin, Quanying Liu, Weiting Sun, Yinuo Zhang, Zhichao Liang","submitted_at":"2024-06-14T12:54:12Z","abstract_excerpt":"The electrical stimulation to the seizure onset zone (SOZ) serves as an efficient approach to seizure suppression. Recently, seizure dynamics have gained widespread attendance in its network propagation mechanisms. Compared with the direct stimulation to SOZ, other brain network-level approaches that can effectively suppress epileptic seizures remain under-explored. In this study, we introduce a platform equipped with a system identification module and a control strategy module, to validate the effectiveness of the hub of the epileptic brain network in suppressing seizure. The identified surro"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2406.09989","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2406.09989/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T08:32:02Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"lsDfzjUhb+6DkqXdBK/wcT5dAFpHUSajyF2zSMJGKBzj9YWJ6vdbi0gN7Od54BTjDukmPBFS6atKliU0OgSUDA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-07T13:25:53.534932Z"},"content_sha256":"dac11d8a18bf487029c507e15d6b249f15bb67a18ea05f26de93b326bb6875cf","schema_version":"1.0","event_id":"sha256:dac11d8a18bf487029c507e15d6b249f15bb67a18ea05f26de93b326bb6875cf"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/5L34KCATIYIR6NDFQPCEG6MGXM/bundle.json","state_url":"https://pith.science/pith/5L34KCATIYIR6NDFQPCEG6MGXM/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/5L34KCATIYIR6NDFQPCEG6MGXM/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-07T13:25:53Z","links":{"resolver":"https://pith.science/pith/5L34KCATIYIR6NDFQPCEG6MGXM","bundle":"https://pith.science/pith/5L34KCATIYIR6NDFQPCEG6MGXM/bundle.json","state":"https://pith.science/pith/5L34KCATIYIR6NDFQPCEG6MGXM/state.json","well_known_bundle":"https://pith.science/.well-known/pith/5L34KCATIYIR6NDFQPCEG6MGXM/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2024:5L34KCATIYIR6NDFQPCEG6MGXM","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"42e1b4b5e898d76973cad78a440daa9e1ba1807af28a57d309d4e12b9fc20522","cross_cats_sorted":["cs.SY","eess.SY"],"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.NC","submitted_at":"2024-06-14T12:54:12Z","title_canon_sha256":"4db1bd58ec4accc0b101215da3f138eed0394b406a9ea1559f01edbb75d16e87"},"schema_version":"1.0","source":{"id":"2406.09989","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2406.09989","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"arxiv_version","alias_value":"2406.09989v1","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2406.09989","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"pith_short_12","alias_value":"5L34KCATIYIR","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"pith_short_16","alias_value":"5L34KCATIYIR6NDF","created_at":"2026-07-05T08:32:02Z"},{"alias_kind":"pith_short_8","alias_value":"5L34KCAT","created_at":"2026-07-05T08:32:02Z"}],"graph_snapshots":[{"event_id":"sha256:dac11d8a18bf487029c507e15d6b249f15bb67a18ea05f26de93b326bb6875cf","target":"graph","created_at":"2026-07-05T08:32:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2406.09989/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"The electrical stimulation to the seizure onset zone (SOZ) serves as an efficient approach to seizure suppression. Recently, seizure dynamics have gained widespread attendance in its network propagation mechanisms. Compared with the direct stimulation to SOZ, other brain network-level approaches that can effectively suppress epileptic seizures remain under-explored. In this study, we introduce a platform equipped with a system identification module and a control strategy module, to validate the effectiveness of the hub of the epileptic brain network in suppressing seizure. The identified surro","authors_text":"Guanyi Zhao, Jialin Wang, Jingzhe Lin, Quanying Liu, Weiting Sun, Yinuo Zhang, Zhichao Liang","cross_cats":["cs.SY","eess.SY"],"headline":"","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.NC","submitted_at":"2024-06-14T12:54:12Z","title":"Suppressing seizure via optimal electrical stimulation to the hub of epileptic brain network"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2406.09989","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:355b3460159c515e8d4ccd95e03ab63726b2f9c35b0924e79f268fcf7d551973","target":"record","created_at":"2026-07-05T08:32:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"42e1b4b5e898d76973cad78a440daa9e1ba1807af28a57d309d4e12b9fc20522","cross_cats_sorted":["cs.SY","eess.SY"],"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.NC","submitted_at":"2024-06-14T12:54:12Z","title_canon_sha256":"4db1bd58ec4accc0b101215da3f138eed0394b406a9ea1559f01edbb75d16e87"},"schema_version":"1.0","source":{"id":"2406.09989","kind":"arxiv","version":1}},"canonical_sha256":"eaf7c5081346111f346583c4437986bb0caf02c15966d3502f5d4ae1f7e2cb14","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"eaf7c5081346111f346583c4437986bb0caf02c15966d3502f5d4ae1f7e2cb14","first_computed_at":"2026-07-05T08:32:02.897602Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T08:32:02.897602Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"L5jRhtZWenQb6G+9sW8KVBxm4zPDKv2Ga3PD0C0FIBqJRyA69yom2QZIZzdVduNFbcv5xKXgh+QUq3ELKM5YBw==","signature_status":"signed_v1","signed_at":"2026-07-05T08:32:02.898100Z","signed_message":"canonical_sha256_bytes"},"source_id":"2406.09989","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:355b3460159c515e8d4ccd95e03ab63726b2f9c35b0924e79f268fcf7d551973","sha256:dac11d8a18bf487029c507e15d6b249f15bb67a18ea05f26de93b326bb6875cf"],"state_sha256":"6bf01b4e12b2920bbc43989b9705b96207009a5466c07ba145ca9e76b5aa681d"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"dVIVU7mIDgfxQW4bWaivPJHDQ3oM39t7wm6ytw2IoiVc8TbuOPTcnP1kpiouFJp1JfCMxhWVwVYZQjXEyZVfDA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-07T13:25:53.538348Z","bundle_sha256":"8474aca4b8419971cdbbc060bdef34e2daa7367130b4c7bb0c69adb9ac6f8baf"}}