{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:5S6AI22RQORQITTTYHGY5WHMJC","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"b667df4130691a80b569961c9a655391f9903d1532093cb80ac8b732f92f6cd7","cross_cats_sorted":["cond-mat.stat-mech"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2018-02-19T09:19:51Z","title_canon_sha256":"cde5f2919851c312800f460dfe1eb6cc7b7a0c87342dc6b83481edc39c87e615"},"schema_version":"1.0","source":{"id":"1802.06560","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1802.06560","created_at":"2026-05-18T00:16:02Z"},{"alias_kind":"arxiv_version","alias_value":"1802.06560v3","created_at":"2026-05-18T00:16:02Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1802.06560","created_at":"2026-05-18T00:16:02Z"},{"alias_kind":"pith_short_12","alias_value":"5S6AI22RQORQ","created_at":"2026-05-18T12:32:08Z"},{"alias_kind":"pith_short_16","alias_value":"5S6AI22RQORQITTT","created_at":"2026-05-18T12:32:08Z"},{"alias_kind":"pith_short_8","alias_value":"5S6AI22R","created_at":"2026-05-18T12:32:08Z"}],"graph_snapshots":[{"event_id":"sha256:a6c6029efbbc7bfd715134be05129629c8f30ec0fdfd55904b022b4e8f561ba2","target":"graph","created_at":"2026-05-18T00:16:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Inferential methods can be used to integrate experimental informations and molecular simulations. The maximum entropy principle provides a framework for using equilibrium experimental data and it has been shown that replica-averaged simulations, restrained using a static potential, are a practical and powerful implementation of such principle. Here we show that replica-averaged simulations restrained using a time-dependent potential are equivalent to the principle of maximum caliber, the dynamic version of the principle of maximum entropy, and thus may allow to integrate time-resolved data in ","authors_text":"Carlo Camilloni, Guido Tiana, Riccardo Capelli","cross_cats":["cond-mat.stat-mech"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2018-02-19T09:19:51Z","title":"An implementation of the maximum-caliber principle by replica-averaged time-resolved restrained simulations"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1802.06560","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:876a432f90a9efc24a1a8cf709135286a6f1489eed351f05d79d56d78b131d1c","target":"record","created_at":"2026-05-18T00:16:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"b667df4130691a80b569961c9a655391f9903d1532093cb80ac8b732f92f6cd7","cross_cats_sorted":["cond-mat.stat-mech"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2018-02-19T09:19:51Z","title_canon_sha256":"cde5f2919851c312800f460dfe1eb6cc7b7a0c87342dc6b83481edc39c87e615"},"schema_version":"1.0","source":{"id":"1802.06560","kind":"arxiv","version":3}},"canonical_sha256":"ecbc046b5183a3044e73c1cd8ed8ec48a9bc921c87cb37f7eb2331ee530f8a64","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ecbc046b5183a3044e73c1cd8ed8ec48a9bc921c87cb37f7eb2331ee530f8a64","first_computed_at":"2026-05-18T00:16:02.842081Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:16:02.842081Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"MgBlidKGv/NMom5YskzBHhKwzAjPEeysCnxcLWEG5X/H4FDBLT8saJBtv/xcyfX5d0lZ8zFMhZgxmqBQEcTiCg==","signature_status":"signed_v1","signed_at":"2026-05-18T00:16:02.842707Z","signed_message":"canonical_sha256_bytes"},"source_id":"1802.06560","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:876a432f90a9efc24a1a8cf709135286a6f1489eed351f05d79d56d78b131d1c","sha256:a6c6029efbbc7bfd715134be05129629c8f30ec0fdfd55904b022b4e8f561ba2"],"state_sha256":"5982b57bd3f7fc8d2c81fdbf86684f341b01a473e94fb94c06efc88cb2486ed4"}