{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2024:5STDEU2RVYDJXVGABL5OVEGNBE","short_pith_number":"pith:5STDEU2R","canonical_record":{"source":{"id":"2409.08395","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2024-09-12T20:48:28Z","cross_cats_sorted":["cs.LG","stat.AP"],"title_canon_sha256":"58648012920edc969d9137c584ca00f2a778b64bf3778d1fc9884fb27ceef461","abstract_canon_sha256":"47474f52e64e5898949ef9631cbd784393e0f9e058ff97ee6853dbcae921f89c"},"schema_version":"1.0"},"canonical_sha256":"eca6325351ae069bd4c00afaea90cd091e65dbf5852aa54d666b7943a5b1f4e9","source":{"kind":"arxiv","id":"2409.08395","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2409.08395","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"arxiv_version","alias_value":"2409.08395v2","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2409.08395","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"pith_short_12","alias_value":"5STDEU2RVYDJ","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"pith_short_16","alias_value":"5STDEU2RVYDJXVGA","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"pith_short_8","alias_value":"5STDEU2R","created_at":"2026-07-05T09:07:31Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2024:5STDEU2RVYDJXVGABL5OVEGNBE","target":"record","payload":{"canonical_record":{"source":{"id":"2409.08395","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2024-09-12T20:48:28Z","cross_cats_sorted":["cs.LG","stat.AP"],"title_canon_sha256":"58648012920edc969d9137c584ca00f2a778b64bf3778d1fc9884fb27ceef461","abstract_canon_sha256":"47474f52e64e5898949ef9631cbd784393e0f9e058ff97ee6853dbcae921f89c"},"schema_version":"1.0"},"canonical_sha256":"eca6325351ae069bd4c00afaea90cd091e65dbf5852aa54d666b7943a5b1f4e9","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T09:07:31.792432Z","signature_b64":"pc52FRNnx5VNJInFiapM41zr++ANyY6d/3JA82A6VfKx0FOx9IFjza6l32J+CwPvKKdstiY9BFce2aX4U5E0CQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"eca6325351ae069bd4c00afaea90cd091e65dbf5852aa54d666b7943a5b1f4e9","last_reissued_at":"2026-07-05T09:07:31.792021Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T09:07:31.792021Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2409.08395","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T09:07:31Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"3C26aZos/A+PlKSZHodY5jMDe8/Pezf2nMj6VfUWiynvPVuWGVjbd6sKu1ayC8LU6Ib+xUVG6o2clSWF6QJtCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-13T18:04:28.534933Z"},"content_sha256":"0877003d31ea3629bb5f16054a2483380b1993ad571c6972a9f9c1760e645dc5","schema_version":"1.0","event_id":"sha256:0877003d31ea3629bb5f16054a2483380b1993ad571c6972a9f9c1760e645dc5"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2024:5STDEU2RVYDJXVGABL5OVEGNBE","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Graphical Structural Learning of rs-fMRI data in Heavy Smokers","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.LG","stat.AP"],"primary_cat":"q-bio.QM","authors_text":"Huili Zheng, Qimin Zhang, Shaohan Chen, Yiru Gong, Zheyan Liu","submitted_at":"2024-09-12T20:48:28Z","abstract_excerpt":"Recent studies revealed structural and functional brain changes in heavy smokers. However, the specific changes in topological brain connections are not well understood. We used Gaussian Undirected Graphs with the graphical lasso algorithm on rs-fMRI data from smokers and non-smokers to identify significant changes in brain connections. Our results indicate high stability in the estimated graphs and identify several brain regions significantly affected by smoking, providing valuable insights for future clinical research."},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2409.08395","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2409.08395/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T09:07:31Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"ORU+S9/akAPareNV5flgsDu7yV/60GM8oD/3q3VU5cPe6kW70fLnbDHj6EZm/97OT3SY9yh7+EPDtB0dUrrdAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-13T18:04:28.535874Z"},"content_sha256":"bf937e030111df6f223f4d016cb5c8f5eefb496e6f00acaccff4d0bb0e8cd2b7","schema_version":"1.0","event_id":"sha256:bf937e030111df6f223f4d016cb5c8f5eefb496e6f00acaccff4d0bb0e8cd2b7"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/5STDEU2RVYDJXVGABL5OVEGNBE/bundle.json","state_url":"https://pith.science/pith/5STDEU2RVYDJXVGABL5OVEGNBE/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/5STDEU2RVYDJXVGABL5OVEGNBE/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-13T18:04:28Z","links":{"resolver":"https://pith.science/pith/5STDEU2RVYDJXVGABL5OVEGNBE","bundle":"https://pith.science/pith/5STDEU2RVYDJXVGABL5OVEGNBE/bundle.json","state":"https://pith.science/pith/5STDEU2RVYDJXVGABL5OVEGNBE/state.json","well_known_bundle":"https://pith.science/.well-known/pith/5STDEU2RVYDJXVGABL5OVEGNBE/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2024:5STDEU2RVYDJXVGABL5OVEGNBE","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"47474f52e64e5898949ef9631cbd784393e0f9e058ff97ee6853dbcae921f89c","cross_cats_sorted":["cs.LG","stat.AP"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2024-09-12T20:48:28Z","title_canon_sha256":"58648012920edc969d9137c584ca00f2a778b64bf3778d1fc9884fb27ceef461"},"schema_version":"1.0","source":{"id":"2409.08395","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2409.08395","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"arxiv_version","alias_value":"2409.08395v2","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2409.08395","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"pith_short_12","alias_value":"5STDEU2RVYDJ","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"pith_short_16","alias_value":"5STDEU2RVYDJXVGA","created_at":"2026-07-05T09:07:31Z"},{"alias_kind":"pith_short_8","alias_value":"5STDEU2R","created_at":"2026-07-05T09:07:31Z"}],"graph_snapshots":[{"event_id":"sha256:bf937e030111df6f223f4d016cb5c8f5eefb496e6f00acaccff4d0bb0e8cd2b7","target":"graph","created_at":"2026-07-05T09:07:31Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2409.08395/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Recent studies revealed structural and functional brain changes in heavy smokers. However, the specific changes in topological brain connections are not well understood. We used Gaussian Undirected Graphs with the graphical lasso algorithm on rs-fMRI data from smokers and non-smokers to identify significant changes in brain connections. Our results indicate high stability in the estimated graphs and identify several brain regions significantly affected by smoking, providing valuable insights for future clinical research.","authors_text":"Huili Zheng, Qimin Zhang, Shaohan Chen, Yiru Gong, Zheyan Liu","cross_cats":["cs.LG","stat.AP"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2024-09-12T20:48:28Z","title":"Graphical Structural Learning of rs-fMRI data in Heavy Smokers"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2409.08395","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:0877003d31ea3629bb5f16054a2483380b1993ad571c6972a9f9c1760e645dc5","target":"record","created_at":"2026-07-05T09:07:31Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"47474f52e64e5898949ef9631cbd784393e0f9e058ff97ee6853dbcae921f89c","cross_cats_sorted":["cs.LG","stat.AP"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2024-09-12T20:48:28Z","title_canon_sha256":"58648012920edc969d9137c584ca00f2a778b64bf3778d1fc9884fb27ceef461"},"schema_version":"1.0","source":{"id":"2409.08395","kind":"arxiv","version":2}},"canonical_sha256":"eca6325351ae069bd4c00afaea90cd091e65dbf5852aa54d666b7943a5b1f4e9","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"eca6325351ae069bd4c00afaea90cd091e65dbf5852aa54d666b7943a5b1f4e9","first_computed_at":"2026-07-05T09:07:31.792021Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T09:07:31.792021Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"pc52FRNnx5VNJInFiapM41zr++ANyY6d/3JA82A6VfKx0FOx9IFjza6l32J+CwPvKKdstiY9BFce2aX4U5E0CQ==","signature_status":"signed_v1","signed_at":"2026-07-05T09:07:31.792432Z","signed_message":"canonical_sha256_bytes"},"source_id":"2409.08395","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:0877003d31ea3629bb5f16054a2483380b1993ad571c6972a9f9c1760e645dc5","sha256:bf937e030111df6f223f4d016cb5c8f5eefb496e6f00acaccff4d0bb0e8cd2b7"],"state_sha256":"ce02a000dc4ea4e8a13ccbe0c981b0409c1463d76b84fd3e503e5801dbda6a34"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"3J8c38sC0NuESMp8gOmUflLzlj5UaBQG/D2gXByI12gT0Hmau26yXtu2gXMOOnCxinO0xpZrSN/CM0SQsyCFBA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-13T18:04:28.543357Z","bundle_sha256":"6a73fe162118cbbade97b6f8b4559d63b383d03a1fb58e6f03557a078e6394a9"}}