{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2021:5YQJHFHQYO6ZBJE26JKWKUTGJA","short_pith_number":"pith:5YQJHFHQ","canonical_record":{"source":{"id":"2107.02584","kind":"arxiv","version":2},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.QM","submitted_at":"2021-07-06T12:53:45Z","cross_cats_sorted":["physics.bio-ph"],"title_canon_sha256":"aea127dc3d6ea51a8b5dff8ec88289c46006b5acd2f2f72df8cd4242f459bd55","abstract_canon_sha256":"134924bb6a101a6e18f01b7ff9e3e6e89ce186f13fc2853cf876920d6340fd5b"},"schema_version":"1.0"},"canonical_sha256":"ee209394f0c3bd90a49af25565526648167a9c7411a49b807070b342768c9c03","source":{"kind":"arxiv","id":"2107.02584","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2107.02584","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"arxiv_version","alias_value":"2107.02584v2","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2107.02584","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"pith_short_12","alias_value":"5YQJHFHQYO6Z","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"pith_short_16","alias_value":"5YQJHFHQYO6ZBJE2","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"pith_short_8","alias_value":"5YQJHFHQ","created_at":"2026-07-05T03:02:16Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2021:5YQJHFHQYO6ZBJE26JKWKUTGJA","target":"record","payload":{"canonical_record":{"source":{"id":"2107.02584","kind":"arxiv","version":2},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.QM","submitted_at":"2021-07-06T12:53:45Z","cross_cats_sorted":["physics.bio-ph"],"title_canon_sha256":"aea127dc3d6ea51a8b5dff8ec88289c46006b5acd2f2f72df8cd4242f459bd55","abstract_canon_sha256":"134924bb6a101a6e18f01b7ff9e3e6e89ce186f13fc2853cf876920d6340fd5b"},"schema_version":"1.0"},"canonical_sha256":"ee209394f0c3bd90a49af25565526648167a9c7411a49b807070b342768c9c03","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T03:02:16.776220Z","signature_b64":"sf9Hpe30tOWhNNXCbMgDWCIuBONjsHCUF1HG4B9yKqvMxAM49to+JuOJFWy/Q+wdUQ8viFuPx+7hmbMlpkRSDg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"ee209394f0c3bd90a49af25565526648167a9c7411a49b807070b342768c9c03","last_reissued_at":"2026-07-05T03:02:16.775821Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T03:02:16.775821Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2107.02584","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T03:02:16Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"etmjmzamkJissNmZfwBhKaMoqx014LNnUkSxDJwg7FMqh92xz4C7HJDMJtrZ0YX/NPMShi8i4ONXz+0605kVAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-21T04:48:49.646213Z"},"content_sha256":"e05a88e751f5bb99651cfac650ad206834922bca5e020950e516f902ce5e0641","schema_version":"1.0","event_id":"sha256:e05a88e751f5bb99651cfac650ad206834922bca5e020950e516f902ce5e0641"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2021:5YQJHFHQYO6ZBJE26JKWKUTGJA","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Deep learning for bioimage analysis","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":["physics.bio-ph"],"primary_cat":"q-bio.QM","authors_text":"Adrien Hallou, Bianca Dumitrascu, Hannah Yevick, Virginie Uhlmann","submitted_at":"2021-07-06T12:53:45Z","abstract_excerpt":"Deep learning has transformed the way large and complex image datasets can be processed, reshaping what is possible in bioimage analysis. As the complexity and size of bioimage data continues to grow, this new analysis paradigm is becoming increasingly ubiquitous. In this Review, we begin by introducing the concepts needed for beginners to understand deep learning. We then review how deep learning has impacted bioimage analysis and explore the open-source resources available to integrate it into a research project. Finally, we discuss the future of deep learning applied to cell and development"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2107.02584","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2107.02584/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T03:02:16Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"GjQlDJ4zAMd3JMsuXv3yLVJEjSQfmB9kJZlztqnYQi5T4xMMSkOVcp2I5rAIdsvQQsFi4nETFQ5yyx7+lP9dCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-21T04:48:49.646791Z"},"content_sha256":"0cbe02f6416291614a2be1497ce0a7961429d98a46e0eb23af1a427cda71f6e6","schema_version":"1.0","event_id":"sha256:0cbe02f6416291614a2be1497ce0a7961429d98a46e0eb23af1a427cda71f6e6"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/5YQJHFHQYO6ZBJE26JKWKUTGJA/bundle.json","state_url":"https://pith.science/pith/5YQJHFHQYO6ZBJE26JKWKUTGJA/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/5YQJHFHQYO6ZBJE26JKWKUTGJA/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-21T04:48:49Z","links":{"resolver":"https://pith.science/pith/5YQJHFHQYO6ZBJE26JKWKUTGJA","bundle":"https://pith.science/pith/5YQJHFHQYO6ZBJE26JKWKUTGJA/bundle.json","state":"https://pith.science/pith/5YQJHFHQYO6ZBJE26JKWKUTGJA/state.json","well_known_bundle":"https://pith.science/.well-known/pith/5YQJHFHQYO6ZBJE26JKWKUTGJA/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2021:5YQJHFHQYO6ZBJE26JKWKUTGJA","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"134924bb6a101a6e18f01b7ff9e3e6e89ce186f13fc2853cf876920d6340fd5b","cross_cats_sorted":["physics.bio-ph"],"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.QM","submitted_at":"2021-07-06T12:53:45Z","title_canon_sha256":"aea127dc3d6ea51a8b5dff8ec88289c46006b5acd2f2f72df8cd4242f459bd55"},"schema_version":"1.0","source":{"id":"2107.02584","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2107.02584","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"arxiv_version","alias_value":"2107.02584v2","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2107.02584","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"pith_short_12","alias_value":"5YQJHFHQYO6Z","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"pith_short_16","alias_value":"5YQJHFHQYO6ZBJE2","created_at":"2026-07-05T03:02:16Z"},{"alias_kind":"pith_short_8","alias_value":"5YQJHFHQ","created_at":"2026-07-05T03:02:16Z"}],"graph_snapshots":[{"event_id":"sha256:0cbe02f6416291614a2be1497ce0a7961429d98a46e0eb23af1a427cda71f6e6","target":"graph","created_at":"2026-07-05T03:02:16Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2107.02584/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Deep learning has transformed the way large and complex image datasets can be processed, reshaping what is possible in bioimage analysis. As the complexity and size of bioimage data continues to grow, this new analysis paradigm is becoming increasingly ubiquitous. In this Review, we begin by introducing the concepts needed for beginners to understand deep learning. We then review how deep learning has impacted bioimage analysis and explore the open-source resources available to integrate it into a research project. Finally, we discuss the future of deep learning applied to cell and development","authors_text":"Adrien Hallou, Bianca Dumitrascu, Hannah Yevick, Virginie Uhlmann","cross_cats":["physics.bio-ph"],"headline":"","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.QM","submitted_at":"2021-07-06T12:53:45Z","title":"Deep learning for bioimage analysis"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2107.02584","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:e05a88e751f5bb99651cfac650ad206834922bca5e020950e516f902ce5e0641","target":"record","created_at":"2026-07-05T03:02:16Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"134924bb6a101a6e18f01b7ff9e3e6e89ce186f13fc2853cf876920d6340fd5b","cross_cats_sorted":["physics.bio-ph"],"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"q-bio.QM","submitted_at":"2021-07-06T12:53:45Z","title_canon_sha256":"aea127dc3d6ea51a8b5dff8ec88289c46006b5acd2f2f72df8cd4242f459bd55"},"schema_version":"1.0","source":{"id":"2107.02584","kind":"arxiv","version":2}},"canonical_sha256":"ee209394f0c3bd90a49af25565526648167a9c7411a49b807070b342768c9c03","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ee209394f0c3bd90a49af25565526648167a9c7411a49b807070b342768c9c03","first_computed_at":"2026-07-05T03:02:16.775821Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T03:02:16.775821Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"sf9Hpe30tOWhNNXCbMgDWCIuBONjsHCUF1HG4B9yKqvMxAM49to+JuOJFWy/Q+wdUQ8viFuPx+7hmbMlpkRSDg==","signature_status":"signed_v1","signed_at":"2026-07-05T03:02:16.776220Z","signed_message":"canonical_sha256_bytes"},"source_id":"2107.02584","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:e05a88e751f5bb99651cfac650ad206834922bca5e020950e516f902ce5e0641","sha256:0cbe02f6416291614a2be1497ce0a7961429d98a46e0eb23af1a427cda71f6e6"],"state_sha256":"799c781afa3bb9653b7c78a283933b34b06901ae05019baa4c381e0a5922a73d"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"6uCPAPHgMHC13opIw8f5MsNhqAeft7ZtSpsyLcEpFowgbPHWcyqNRhXy3GMY/q457PNeuQn6mevoQGoZ02VCBg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-21T04:48:49.652253Z","bundle_sha256":"cf731a9baabab62fafeba3296a79085a32885e4c919eed99d6b759a7a23d9f61"}}