{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2013:62KAAPGMNFEZHUG2BXSCYCIODV","short_pith_number":"pith:62KAAPGM","schema_version":"1.0","canonical_sha256":"f694003ccc694993d0da0de42c090e1d5044678fb67c10af43fe471da848f184","source":{"kind":"arxiv","id":"1312.4576","version":2},"attestation_state":"computed","paper":{"title":"The jigsaw puzzle of sequence phenotype inference: Piecing together Shannon entropy, importance sampling, and Empirical Bayes","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.QM","authors_text":"Deborah A. Striegel, Vipul Periwal, Zeina Shreif","submitted_at":"2013-12-16T21:55:10Z","abstract_excerpt":"A nucleotide sequence 35 base pairs long can take 1,180,591,620,717,411,303,424 possible values. An example of systems biology datasets, protein binding microarrays, contain activity data from about 40000 such sequences. The discrepancy between the number of possible configurations and the available activities is enormous. Thus, albeit that systems biology datasets are large in absolute terms, they oftentimes require methods developed for rare events due to the combinatorial increase in the number of possible configurations of biological systems. A plethora of techniques for handling large dat"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1312.4576","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2013-12-16T21:55:10Z","cross_cats_sorted":[],"title_canon_sha256":"8313148f0f30ba208838913dc1880d749e17cb55637106eeae946f0a3ec749b0","abstract_canon_sha256":"07925a924d885102e0f89e4f99afb131a9588fa68e8343c472b65685feb53e18"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:51:25.351151Z","signature_b64":"xdhMzg2p0MYeYSmEBM2lCUklLdjLu77X1gpICRjnPqKrY1zC8YrdfbAMlL+y0EjgSMOltP62zw2u9NdvsZhYBw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"f694003ccc694993d0da0de42c090e1d5044678fb67c10af43fe471da848f184","last_reissued_at":"2026-05-18T01:51:25.350627Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:51:25.350627Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"The jigsaw puzzle of sequence phenotype inference: Piecing together Shannon entropy, importance sampling, and Empirical Bayes","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.QM","authors_text":"Deborah A. Striegel, Vipul Periwal, Zeina Shreif","submitted_at":"2013-12-16T21:55:10Z","abstract_excerpt":"A nucleotide sequence 35 base pairs long can take 1,180,591,620,717,411,303,424 possible values. An example of systems biology datasets, protein binding microarrays, contain activity data from about 40000 such sequences. The discrepancy between the number of possible configurations and the available activities is enormous. Thus, albeit that systems biology datasets are large in absolute terms, they oftentimes require methods developed for rare events due to the combinatorial increase in the number of possible configurations of biological systems. A plethora of techniques for handling large dat"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1312.4576","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1312.4576","created_at":"2026-05-18T01:51:25.350711+00:00"},{"alias_kind":"arxiv_version","alias_value":"1312.4576v2","created_at":"2026-05-18T01:51:25.350711+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1312.4576","created_at":"2026-05-18T01:51:25.350711+00:00"},{"alias_kind":"pith_short_12","alias_value":"62KAAPGMNFEZ","created_at":"2026-05-18T12:27:34.582898+00:00"},{"alias_kind":"pith_short_16","alias_value":"62KAAPGMNFEZHUG2","created_at":"2026-05-18T12:27:34.582898+00:00"},{"alias_kind":"pith_short_8","alias_value":"62KAAPGM","created_at":"2026-05-18T12:27:34.582898+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/62KAAPGMNFEZHUG2BXSCYCIODV","json":"https://pith.science/pith/62KAAPGMNFEZHUG2BXSCYCIODV.json","graph_json":"https://pith.science/api/pith-number/62KAAPGMNFEZHUG2BXSCYCIODV/graph.json","events_json":"https://pith.science/api/pith-number/62KAAPGMNFEZHUG2BXSCYCIODV/events.json","paper":"https://pith.science/paper/62KAAPGM"},"agent_actions":{"view_html":"https://pith.science/pith/62KAAPGMNFEZHUG2BXSCYCIODV","download_json":"https://pith.science/pith/62KAAPGMNFEZHUG2BXSCYCIODV.json","view_paper":"https://pith.science/paper/62KAAPGM","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1312.4576&json=true","fetch_graph":"https://pith.science/api/pith-number/62KAAPGMNFEZHUG2BXSCYCIODV/graph.json","fetch_events":"https://pith.science/api/pith-number/62KAAPGMNFEZHUG2BXSCYCIODV/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/62KAAPGMNFEZHUG2BXSCYCIODV/action/timestamp_anchor","attest_storage":"https://pith.science/pith/62KAAPGMNFEZHUG2BXSCYCIODV/action/storage_attestation","attest_author":"https://pith.science/pith/62KAAPGMNFEZHUG2BXSCYCIODV/action/author_attestation","sign_citation":"https://pith.science/pith/62KAAPGMNFEZHUG2BXSCYCIODV/action/citation_signature","submit_replication":"https://pith.science/pith/62KAAPGMNFEZHUG2BXSCYCIODV/action/replication_record"}},"created_at":"2026-05-18T01:51:25.350711+00:00","updated_at":"2026-05-18T01:51:25.350711+00:00"}