{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2018:6R6N5L5C7753CIPS2WFWSL76XG","short_pith_number":"pith:6R6N5L5C","schema_version":"1.0","canonical_sha256":"f47cdeafa2fffbb121f2d58b692ffeb9b9452ae300cef9782c188f43bb77b9b1","source":{"kind":"arxiv","id":"1811.07661","version":1},"attestation_state":"computed","paper":{"title":"Networks of ribosome flow models for modeling and analyzing intracellular traffic","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.MN","authors_text":"Alexander Ovseevich, Itzik Nanikashvili, Michael Margaliot, Tamir Tuller, Yoram Zarai","submitted_at":"2018-11-19T13:07:42Z","abstract_excerpt":"The ribosome flow model with input and output (RFMIO) is a deterministic dynamical system that has been used to study the flow of ribosomes during mRNA translation. The RFMIO and its variants encapsulate important properties that are relevant to modeling ribosome flow such as the possible evolution of \"traffic jams\" and non-homogeneous elongation rates along the mRNA molecule, and can also be used for studying additional intracellular processes such as transcription, transport, and more. Here we consider networks of interconnected RFMIOs as a fundamental tool for modeling, analyzing and re-eng"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1811.07661","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2018-11-19T13:07:42Z","cross_cats_sorted":[],"title_canon_sha256":"c57811811c73d1811af58c682c42b2496db549bff38ce2a2f59e92486b8ee1c7","abstract_canon_sha256":"5dd8cd7091f537087f605ee49804aed0bc69362a25a31477bcd5bb67f240fc91"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:00:23.836306Z","signature_b64":"tn1303hF1Q74eSl50geDz769RxKtpKCNU8MaRHys5rYFa18WjlZg2+bv1ux0JmNTBI2VqkMmgLx3TzlCGtoEBQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"f47cdeafa2fffbb121f2d58b692ffeb9b9452ae300cef9782c188f43bb77b9b1","last_reissued_at":"2026-05-18T00:00:23.835758Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:00:23.835758Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Networks of ribosome flow models for modeling and analyzing intracellular traffic","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.MN","authors_text":"Alexander Ovseevich, Itzik Nanikashvili, Michael Margaliot, Tamir Tuller, Yoram Zarai","submitted_at":"2018-11-19T13:07:42Z","abstract_excerpt":"The ribosome flow model with input and output (RFMIO) is a deterministic dynamical system that has been used to study the flow of ribosomes during mRNA translation. The RFMIO and its variants encapsulate important properties that are relevant to modeling ribosome flow such as the possible evolution of \"traffic jams\" and non-homogeneous elongation rates along the mRNA molecule, and can also be used for studying additional intracellular processes such as transcription, transport, and more. Here we consider networks of interconnected RFMIOs as a fundamental tool for modeling, analyzing and re-eng"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1811.07661","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1811.07661","created_at":"2026-05-18T00:00:23.835866+00:00"},{"alias_kind":"arxiv_version","alias_value":"1811.07661v1","created_at":"2026-05-18T00:00:23.835866+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1811.07661","created_at":"2026-05-18T00:00:23.835866+00:00"},{"alias_kind":"pith_short_12","alias_value":"6R6N5L5C7753","created_at":"2026-05-18T12:32:11.075285+00:00"},{"alias_kind":"pith_short_16","alias_value":"6R6N5L5C7753CIPS","created_at":"2026-05-18T12:32:11.075285+00:00"},{"alias_kind":"pith_short_8","alias_value":"6R6N5L5C","created_at":"2026-05-18T12:32:11.075285+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/6R6N5L5C7753CIPS2WFWSL76XG","json":"https://pith.science/pith/6R6N5L5C7753CIPS2WFWSL76XG.json","graph_json":"https://pith.science/api/pith-number/6R6N5L5C7753CIPS2WFWSL76XG/graph.json","events_json":"https://pith.science/api/pith-number/6R6N5L5C7753CIPS2WFWSL76XG/events.json","paper":"https://pith.science/paper/6R6N5L5C"},"agent_actions":{"view_html":"https://pith.science/pith/6R6N5L5C7753CIPS2WFWSL76XG","download_json":"https://pith.science/pith/6R6N5L5C7753CIPS2WFWSL76XG.json","view_paper":"https://pith.science/paper/6R6N5L5C","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1811.07661&json=true","fetch_graph":"https://pith.science/api/pith-number/6R6N5L5C7753CIPS2WFWSL76XG/graph.json","fetch_events":"https://pith.science/api/pith-number/6R6N5L5C7753CIPS2WFWSL76XG/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/6R6N5L5C7753CIPS2WFWSL76XG/action/timestamp_anchor","attest_storage":"https://pith.science/pith/6R6N5L5C7753CIPS2WFWSL76XG/action/storage_attestation","attest_author":"https://pith.science/pith/6R6N5L5C7753CIPS2WFWSL76XG/action/author_attestation","sign_citation":"https://pith.science/pith/6R6N5L5C7753CIPS2WFWSL76XG/action/citation_signature","submit_replication":"https://pith.science/pith/6R6N5L5C7753CIPS2WFWSL76XG/action/replication_record"}},"created_at":"2026-05-18T00:00:23.835866+00:00","updated_at":"2026-05-18T00:00:23.835866+00:00"}