{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2026:6TBFN5FVEAHKRQRQ6LQMB6CL6V","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"962b7fbe3fd22151ad81dcfc0e642274d03d329376c06deed52ada91272af9fb","cross_cats_sorted":["q-bio.QM"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.LG","submitted_at":"2026-06-10T09:43:30Z","title_canon_sha256":"0d553086119b325f6ddbff45aaf0e6acf175e4ccae5277a2d0125538c546b0a4"},"schema_version":"1.0","source":{"id":"2606.11868","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2606.11868","created_at":"2026-06-11T01:10:12Z"},{"alias_kind":"arxiv_version","alias_value":"2606.11868v1","created_at":"2026-06-11T01:10:12Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2606.11868","created_at":"2026-06-11T01:10:12Z"},{"alias_kind":"pith_short_12","alias_value":"6TBFN5FVEAHK","created_at":"2026-06-11T01:10:12Z"},{"alias_kind":"pith_short_16","alias_value":"6TBFN5FVEAHKRQRQ","created_at":"2026-06-11T01:10:12Z"},{"alias_kind":"pith_short_8","alias_value":"6TBFN5FV","created_at":"2026-06-11T01:10:12Z"}],"graph_snapshots":[{"event_id":"sha256:3bfc0b4f0e04e885632d66d9bba3f66fcbe241d0bcb66c9a4d8b16852b57b91e","target":"graph","created_at":"2026-06-11T01:10:12Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2606.11868/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"De novo peptide sequencing from tandem mass spectrometry is pivotal in proteomics, enabling identification of novel peptides without reference databases. While recent Transformer-based encoder-decoder models have achieved remarkable performance, we uncover a critical pathology in their inference dynamics. Through comprehensive feature scaling experiments, we demonstrate that existing auto-regressive peptide decoders tend to over-rely on generated-sequence priors while progressively under-utilizing fine-grained physical evidence from the input mass spectrum. This phenomenon leads to suboptimal ","authors_text":"Dongxin Lyu, Hongxin Xiang, Jingbo Zhou, Jun Xia, Yuqiang Li","cross_cats":["q-bio.QM"],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.LG","submitted_at":"2026-06-10T09:43:30Z","title":"MemNovo: Look Back at the Spectrum for Balanced De Novo Peptide Sequencing from Mass Spectrometry"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2606.11868","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:94cf2e7d0ea1b18e5461fd55dced5300945ffbbee3707d07eab9d2a916442d58","target":"record","created_at":"2026-06-11T01:10:12Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"962b7fbe3fd22151ad81dcfc0e642274d03d329376c06deed52ada91272af9fb","cross_cats_sorted":["q-bio.QM"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.LG","submitted_at":"2026-06-10T09:43:30Z","title_canon_sha256":"0d553086119b325f6ddbff45aaf0e6acf175e4ccae5277a2d0125538c546b0a4"},"schema_version":"1.0","source":{"id":"2606.11868","kind":"arxiv","version":1}},"canonical_sha256":"f4c256f4b5200ea8c230f2e0c0f84bf57cd22de95f74d0fb051169a9b71860ef","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"f4c256f4b5200ea8c230f2e0c0f84bf57cd22de95f74d0fb051169a9b71860ef","first_computed_at":"2026-06-11T01:10:12.729249Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-06-11T01:10:12.729249Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"RreVdYkGUycHE3Y/CMGYLC44Jkw8NoxGoKAotgMWo7YCreDo+F1WS+93dQOOCSz8p3/sYDf+WUUDeH2PpMVbCg==","signature_status":"signed_v1","signed_at":"2026-06-11T01:10:12.730070Z","signed_message":"canonical_sha256_bytes"},"source_id":"2606.11868","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:94cf2e7d0ea1b18e5461fd55dced5300945ffbbee3707d07eab9d2a916442d58","sha256:3bfc0b4f0e04e885632d66d9bba3f66fcbe241d0bcb66c9a4d8b16852b57b91e"],"state_sha256":"55fd5cde783a4f1c132bd3728179a7ffc5cb73ebf68549cc6882ffbe4d1b22c5"}