{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2015:6TZF6X5AAYTVVUJ7ULDJQF7DCE","short_pith_number":"pith:6TZF6X5A","canonical_record":{"source":{"id":"1506.09005","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-30T09:32:25Z","cross_cats_sorted":[],"title_canon_sha256":"5fbffc9f9f0ebdebb59da871e6f96f1532e59f3e4dce86c1658d8e0abf012a80","abstract_canon_sha256":"04202e697ded4ef468c4db35f89210b76d3b70eafc514e739dfb0154caef3eeb"},"schema_version":"1.0"},"canonical_sha256":"f4f25f5fa006275ad13fa2c69817e3113363b31aba4ff77f1fdf1baf7915a39f","source":{"kind":"arxiv","id":"1506.09005","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1506.09005","created_at":"2026-05-18T01:37:33Z"},{"alias_kind":"arxiv_version","alias_value":"1506.09005v1","created_at":"2026-05-18T01:37:33Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1506.09005","created_at":"2026-05-18T01:37:33Z"},{"alias_kind":"pith_short_12","alias_value":"6TZF6X5AAYTV","created_at":"2026-05-18T12:29:07Z"},{"alias_kind":"pith_short_16","alias_value":"6TZF6X5AAYTVVUJ7","created_at":"2026-05-18T12:29:07Z"},{"alias_kind":"pith_short_8","alias_value":"6TZF6X5A","created_at":"2026-05-18T12:29:07Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2015:6TZF6X5AAYTVVUJ7ULDJQF7DCE","target":"record","payload":{"canonical_record":{"source":{"id":"1506.09005","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-30T09:32:25Z","cross_cats_sorted":[],"title_canon_sha256":"5fbffc9f9f0ebdebb59da871e6f96f1532e59f3e4dce86c1658d8e0abf012a80","abstract_canon_sha256":"04202e697ded4ef468c4db35f89210b76d3b70eafc514e739dfb0154caef3eeb"},"schema_version":"1.0"},"canonical_sha256":"f4f25f5fa006275ad13fa2c69817e3113363b31aba4ff77f1fdf1baf7915a39f","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:37:33.892570Z","signature_b64":"eRfTizMhJOR4U4rI8mfJf6qPy3UDr41Q+lXe+MFLtUYVjx+ukT0MrRVLVfpuTVAGUKuokENAQHELp7rkRbJYCQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"f4f25f5fa006275ad13fa2c69817e3113363b31aba4ff77f1fdf1baf7915a39f","last_reissued_at":"2026-05-18T01:37:33.892101Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:37:33.892101Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1506.09005","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:37:33Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"zmKi4UkeQLeWWa/UqKN5M0jZhIerPAGvuGzFkPeYCveosg09iAW2qFQGYHuEDoujqoBwXCuhK5pd2pM1J+RxAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-03T01:46:57.850468Z"},"content_sha256":"bffc0e3e803ac65797532e2fa95dc68fb91c119b2e06e71cb652fc38c11eeffd","schema_version":"1.0","event_id":"sha256:bffc0e3e803ac65797532e2fa95dc68fb91c119b2e06e71cb652fc38c11eeffd"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2015:6TZF6X5AAYTVVUJ7ULDJQF7DCE","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Coarse-grained modelling of strong DNA bending I: Thermodynamics and comparison to an experimental \"molecular vice\"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.BM","authors_text":"Ard A. Louis, Flavio Romano, Jonathan P.K. Doye, Ryan M. Harrison, Thomas E. Ouldridge","submitted_at":"2015-06-30T09:32:25Z","abstract_excerpt":"DNA bending is biologically important for genome regulation and is relevant to a range of nanotechnological systems. Recent results suggest that sharp bending is much easier than implied by the widely-used worm-like chain model; many of these studies, however, remain controversial. We use a coarse-grained model, previously fitted to DNA's basic thermodynamic and mechanical properties, to explore strongly bent systems. We find that as the end-to-end distance is decreased sufficiently short duplexes undergo a transition to a state in which the bending strain is localized at a flexible kink that "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1506.09005","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:37:33Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"bxebeu19dAXOROckDSmZgNiN5ikva2cQaXljCpN8bc5iO6IKs/n4DASVyy0l9Okcby2LkwoQ5M9Cu6k4JsJ0Bw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-03T01:46:57.850817Z"},"content_sha256":"4c3aed39135d826951644e6f924f0f404e10fefa9be5b1380abcf34ec5a4615d","schema_version":"1.0","event_id":"sha256:4c3aed39135d826951644e6f924f0f404e10fefa9be5b1380abcf34ec5a4615d"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/6TZF6X5AAYTVVUJ7ULDJQF7DCE/bundle.json","state_url":"https://pith.science/pith/6TZF6X5AAYTVVUJ7ULDJQF7DCE/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/6TZF6X5AAYTVVUJ7ULDJQF7DCE/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-03T01:46:57Z","links":{"resolver":"https://pith.science/pith/6TZF6X5AAYTVVUJ7ULDJQF7DCE","bundle":"https://pith.science/pith/6TZF6X5AAYTVVUJ7ULDJQF7DCE/bundle.json","state":"https://pith.science/pith/6TZF6X5AAYTVVUJ7ULDJQF7DCE/state.json","well_known_bundle":"https://pith.science/.well-known/pith/6TZF6X5AAYTVVUJ7ULDJQF7DCE/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2015:6TZF6X5AAYTVVUJ7ULDJQF7DCE","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"04202e697ded4ef468c4db35f89210b76d3b70eafc514e739dfb0154caef3eeb","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-30T09:32:25Z","title_canon_sha256":"5fbffc9f9f0ebdebb59da871e6f96f1532e59f3e4dce86c1658d8e0abf012a80"},"schema_version":"1.0","source":{"id":"1506.09005","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1506.09005","created_at":"2026-05-18T01:37:33Z"},{"alias_kind":"arxiv_version","alias_value":"1506.09005v1","created_at":"2026-05-18T01:37:33Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1506.09005","created_at":"2026-05-18T01:37:33Z"},{"alias_kind":"pith_short_12","alias_value":"6TZF6X5AAYTV","created_at":"2026-05-18T12:29:07Z"},{"alias_kind":"pith_short_16","alias_value":"6TZF6X5AAYTVVUJ7","created_at":"2026-05-18T12:29:07Z"},{"alias_kind":"pith_short_8","alias_value":"6TZF6X5A","created_at":"2026-05-18T12:29:07Z"}],"graph_snapshots":[{"event_id":"sha256:4c3aed39135d826951644e6f924f0f404e10fefa9be5b1380abcf34ec5a4615d","target":"graph","created_at":"2026-05-18T01:37:33Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"DNA bending is biologically important for genome regulation and is relevant to a range of nanotechnological systems. Recent results suggest that sharp bending is much easier than implied by the widely-used worm-like chain model; many of these studies, however, remain controversial. We use a coarse-grained model, previously fitted to DNA's basic thermodynamic and mechanical properties, to explore strongly bent systems. We find that as the end-to-end distance is decreased sufficiently short duplexes undergo a transition to a state in which the bending strain is localized at a flexible kink that ","authors_text":"Ard A. Louis, Flavio Romano, Jonathan P.K. Doye, Ryan M. Harrison, Thomas E. Ouldridge","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-30T09:32:25Z","title":"Coarse-grained modelling of strong DNA bending I: Thermodynamics and comparison to an experimental \"molecular vice\""},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1506.09005","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:bffc0e3e803ac65797532e2fa95dc68fb91c119b2e06e71cb652fc38c11eeffd","target":"record","created_at":"2026-05-18T01:37:33Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"04202e697ded4ef468c4db35f89210b76d3b70eafc514e739dfb0154caef3eeb","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-30T09:32:25Z","title_canon_sha256":"5fbffc9f9f0ebdebb59da871e6f96f1532e59f3e4dce86c1658d8e0abf012a80"},"schema_version":"1.0","source":{"id":"1506.09005","kind":"arxiv","version":1}},"canonical_sha256":"f4f25f5fa006275ad13fa2c69817e3113363b31aba4ff77f1fdf1baf7915a39f","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"f4f25f5fa006275ad13fa2c69817e3113363b31aba4ff77f1fdf1baf7915a39f","first_computed_at":"2026-05-18T01:37:33.892101Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:37:33.892101Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"eRfTizMhJOR4U4rI8mfJf6qPy3UDr41Q+lXe+MFLtUYVjx+ukT0MrRVLVfpuTVAGUKuokENAQHELp7rkRbJYCQ==","signature_status":"signed_v1","signed_at":"2026-05-18T01:37:33.892570Z","signed_message":"canonical_sha256_bytes"},"source_id":"1506.09005","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:bffc0e3e803ac65797532e2fa95dc68fb91c119b2e06e71cb652fc38c11eeffd","sha256:4c3aed39135d826951644e6f924f0f404e10fefa9be5b1380abcf34ec5a4615d"],"state_sha256":"8c6c1848217b3b3dfddf2958e6c6008cfafee5da369662d57cc327628278e1b7"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"tvKGgVxip7zDtKypW88s2Zz7Uy9U43bNJVrCb0nT/2qUTCFIdl+levGx4SUUY2XkMsnA4lF1dUvj2X1eEFBsCg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-03T01:46:57.852795Z","bundle_sha256":"d01695c9056d6675538a8b03a81e9459da376b9fd84aee1f5507dee812815f91"}}