{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2014:72FP7TGL4VPGRBBCFNOY2R73LY","short_pith_number":"pith:72FP7TGL","canonical_record":{"source":{"id":"1405.3310","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-05-13T21:22:11Z","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"title_canon_sha256":"ebeb3d89b1b59630be3f8eefe1f1fdc8e37c5266b5f171cd465c7423ebad3cca","abstract_canon_sha256":"6a4c5b07e1424adc12ef6ef9e3068b3258c8aaae87a48d604fd9657493da524f"},"schema_version":"1.0"},"canonical_sha256":"fe8affcccbe55e6884222b5d8d47fb5e0e059806f6710d1779aff3dcdfad8e84","source":{"kind":"arxiv","id":"1405.3310","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1405.3310","created_at":"2026-05-18T02:51:56Z"},{"alias_kind":"arxiv_version","alias_value":"1405.3310v1","created_at":"2026-05-18T02:51:56Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1405.3310","created_at":"2026-05-18T02:51:56Z"},{"alias_kind":"pith_short_12","alias_value":"72FP7TGL4VPG","created_at":"2026-05-18T12:28:16Z"},{"alias_kind":"pith_short_16","alias_value":"72FP7TGL4VPGRBBC","created_at":"2026-05-18T12:28:16Z"},{"alias_kind":"pith_short_8","alias_value":"72FP7TGL","created_at":"2026-05-18T12:28:16Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2014:72FP7TGL4VPGRBBCFNOY2R73LY","target":"record","payload":{"canonical_record":{"source":{"id":"1405.3310","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-05-13T21:22:11Z","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"title_canon_sha256":"ebeb3d89b1b59630be3f8eefe1f1fdc8e37c5266b5f171cd465c7423ebad3cca","abstract_canon_sha256":"6a4c5b07e1424adc12ef6ef9e3068b3258c8aaae87a48d604fd9657493da524f"},"schema_version":"1.0"},"canonical_sha256":"fe8affcccbe55e6884222b5d8d47fb5e0e059806f6710d1779aff3dcdfad8e84","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T02:51:56.434834Z","signature_b64":"y/qPG0wpa8phIGbedC1ykA4BlKTvbEQ2L/qrlimLlirDVb16MslTpf/EPISG2QEPzgL5Hc1wUcgtwBXpg4qzCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"fe8affcccbe55e6884222b5d8d47fb5e0e059806f6710d1779aff3dcdfad8e84","last_reissued_at":"2026-05-18T02:51:56.434297Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T02:51:56.434297Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1405.3310","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:51:56Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"tDFbVgES0GvTpCok/7ozQ9o8mskavCuTyAw3QvwZKpPEdeD4DKACpvQAptPC9lm/42h0x3F3YHe0qdq+q2T0Cw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-29T11:57:31.441074Z"},"content_sha256":"8b3132cb4d3d266dac4b87812a055b4cf988219c2348126948b6c548f721bcad","schema_version":"1.0","event_id":"sha256:8b3132cb4d3d266dac4b87812a055b4cf988219c2348126948b6c548f721bcad"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2014:72FP7TGL4VPGRBBCFNOY2R73LY","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Pathways for virus assembly around nucleic acids","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft","physics.bio-ph"],"primary_cat":"q-bio.BM","authors_text":"Jason D Perlmutter, Matthew R Perkett, Michael F Hagan","submitted_at":"2014-05-13T21:22:11Z","abstract_excerpt":"Understanding the pathways by which viral capsid proteins assemble around their genomes could identify key intermediates as potential drug targets. In this work we use computer simulations to characterize assembly over a wide range of capsid protein-protein interaction strengths and solution ionic strengths. We find that assembly pathways can be categorized into two classes, in which intermediates are either predominantly ordered or disordered. Our results suggest that estimating the protein-protein and the protein-genome binding affinities may be sufficient to predict which pathway occurs. Fu"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1405.3310","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:51:56Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"9pvrxZnaUggFdWxzgVKBbewrVcqQkhxEd5MgpIjNJpZNXBkhAzxNcdw0zT/cVcL2zmhRZU4FKOIBSLcpqJQSAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-29T11:57:31.441433Z"},"content_sha256":"850170ffd2ce3184ac925e73073e30a01cfbc10d71ffd7f592fd67070719f311","schema_version":"1.0","event_id":"sha256:850170ffd2ce3184ac925e73073e30a01cfbc10d71ffd7f592fd67070719f311"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/72FP7TGL4VPGRBBCFNOY2R73LY/bundle.json","state_url":"https://pith.science/pith/72FP7TGL4VPGRBBCFNOY2R73LY/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/72FP7TGL4VPGRBBCFNOY2R73LY/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-29T11:57:31Z","links":{"resolver":"https://pith.science/pith/72FP7TGL4VPGRBBCFNOY2R73LY","bundle":"https://pith.science/pith/72FP7TGL4VPGRBBCFNOY2R73LY/bundle.json","state":"https://pith.science/pith/72FP7TGL4VPGRBBCFNOY2R73LY/state.json","well_known_bundle":"https://pith.science/.well-known/pith/72FP7TGL4VPGRBBCFNOY2R73LY/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2014:72FP7TGL4VPGRBBCFNOY2R73LY","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"6a4c5b07e1424adc12ef6ef9e3068b3258c8aaae87a48d604fd9657493da524f","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-05-13T21:22:11Z","title_canon_sha256":"ebeb3d89b1b59630be3f8eefe1f1fdc8e37c5266b5f171cd465c7423ebad3cca"},"schema_version":"1.0","source":{"id":"1405.3310","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1405.3310","created_at":"2026-05-18T02:51:56Z"},{"alias_kind":"arxiv_version","alias_value":"1405.3310v1","created_at":"2026-05-18T02:51:56Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1405.3310","created_at":"2026-05-18T02:51:56Z"},{"alias_kind":"pith_short_12","alias_value":"72FP7TGL4VPG","created_at":"2026-05-18T12:28:16Z"},{"alias_kind":"pith_short_16","alias_value":"72FP7TGL4VPGRBBC","created_at":"2026-05-18T12:28:16Z"},{"alias_kind":"pith_short_8","alias_value":"72FP7TGL","created_at":"2026-05-18T12:28:16Z"}],"graph_snapshots":[{"event_id":"sha256:850170ffd2ce3184ac925e73073e30a01cfbc10d71ffd7f592fd67070719f311","target":"graph","created_at":"2026-05-18T02:51:56Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Understanding the pathways by which viral capsid proteins assemble around their genomes could identify key intermediates as potential drug targets. In this work we use computer simulations to characterize assembly over a wide range of capsid protein-protein interaction strengths and solution ionic strengths. We find that assembly pathways can be categorized into two classes, in which intermediates are either predominantly ordered or disordered. Our results suggest that estimating the protein-protein and the protein-genome binding affinities may be sufficient to predict which pathway occurs. Fu","authors_text":"Jason D Perlmutter, Matthew R Perkett, Michael F Hagan","cross_cats":["cond-mat.soft","physics.bio-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-05-13T21:22:11Z","title":"Pathways for virus assembly around nucleic acids"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1405.3310","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:8b3132cb4d3d266dac4b87812a055b4cf988219c2348126948b6c548f721bcad","target":"record","created_at":"2026-05-18T02:51:56Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"6a4c5b07e1424adc12ef6ef9e3068b3258c8aaae87a48d604fd9657493da524f","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2014-05-13T21:22:11Z","title_canon_sha256":"ebeb3d89b1b59630be3f8eefe1f1fdc8e37c5266b5f171cd465c7423ebad3cca"},"schema_version":"1.0","source":{"id":"1405.3310","kind":"arxiv","version":1}},"canonical_sha256":"fe8affcccbe55e6884222b5d8d47fb5e0e059806f6710d1779aff3dcdfad8e84","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"fe8affcccbe55e6884222b5d8d47fb5e0e059806f6710d1779aff3dcdfad8e84","first_computed_at":"2026-05-18T02:51:56.434297Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T02:51:56.434297Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"y/qPG0wpa8phIGbedC1ykA4BlKTvbEQ2L/qrlimLlirDVb16MslTpf/EPISG2QEPzgL5Hc1wUcgtwBXpg4qzCA==","signature_status":"signed_v1","signed_at":"2026-05-18T02:51:56.434834Z","signed_message":"canonical_sha256_bytes"},"source_id":"1405.3310","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:8b3132cb4d3d266dac4b87812a055b4cf988219c2348126948b6c548f721bcad","sha256:850170ffd2ce3184ac925e73073e30a01cfbc10d71ffd7f592fd67070719f311"],"state_sha256":"f6da92b09c3a5621b58ab3148adc7a962635a173c447a62ea81ec62a81ef6915"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"iQUfN97XQ6EgFbRUP/dFIKUxpFGVyErjWiBGjRkzi2MqRGt67KN9ssaOefoNw/6n2lvxN7imrOkXUbC8NLe7Dg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-29T11:57:31.443273Z","bundle_sha256":"ea14486d09bd154831e31fd9b59ee9a8297240dac404c8510fe4444c5ca6686c"}}