{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2011:7AUEWOEFK4VDHYE52GW2ZO6U5F","short_pith_number":"pith:7AUEWOEF","canonical_record":{"source":{"id":"1102.0610","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-02-03T07:38:18Z","cross_cats_sorted":["cond-mat.soft","q-bio.SC"],"title_canon_sha256":"790d534863dde733683c084637fecfe3ff7add9cc93be13aafaa22d3d3b00b92","abstract_canon_sha256":"00b96a1086582c4c939dccc1d0508995c44fa027f68c7f7b70432fb9b0f08e3e"},"schema_version":"1.0"},"canonical_sha256":"f8284b3885572a33e09dd1adacbbd4e94f313475db95f733abca2084fd3aba8b","source":{"kind":"arxiv","id":"1102.0610","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1102.0610","created_at":"2026-05-18T04:30:03Z"},{"alias_kind":"arxiv_version","alias_value":"1102.0610v1","created_at":"2026-05-18T04:30:03Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1102.0610","created_at":"2026-05-18T04:30:03Z"},{"alias_kind":"pith_short_12","alias_value":"7AUEWOEFK4VD","created_at":"2026-05-18T12:26:22Z"},{"alias_kind":"pith_short_16","alias_value":"7AUEWOEFK4VDHYE5","created_at":"2026-05-18T12:26:22Z"},{"alias_kind":"pith_short_8","alias_value":"7AUEWOEF","created_at":"2026-05-18T12:26:22Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2011:7AUEWOEFK4VDHYE52GW2ZO6U5F","target":"record","payload":{"canonical_record":{"source":{"id":"1102.0610","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-02-03T07:38:18Z","cross_cats_sorted":["cond-mat.soft","q-bio.SC"],"title_canon_sha256":"790d534863dde733683c084637fecfe3ff7add9cc93be13aafaa22d3d3b00b92","abstract_canon_sha256":"00b96a1086582c4c939dccc1d0508995c44fa027f68c7f7b70432fb9b0f08e3e"},"schema_version":"1.0"},"canonical_sha256":"f8284b3885572a33e09dd1adacbbd4e94f313475db95f733abca2084fd3aba8b","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T04:30:03.616695Z","signature_b64":"SsSi2nCCXU5vYGlvxoZ/TApm+3J9CTh/j5CQ7SFk6zY2yC8aywIb0hmfjWyLfSShavV7cfopf1GovnWxoY57Ag==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"f8284b3885572a33e09dd1adacbbd4e94f313475db95f733abca2084fd3aba8b","last_reissued_at":"2026-05-18T04:30:03.616293Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T04:30:03.616293Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1102.0610","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:30:03Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"uiJ1MEQzM/qvdAhV1IFivbc3QezqZ1plDj2WwSwk3Th4fS9x466M30NLlZKl3nE8cA59COewoLjPephGTwReBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-11T10:13:50.142435Z"},"content_sha256":"48f3db740d01d717a47e9d0657bfeb3af710e29b0e93949d47b857bd3bda0886","schema_version":"1.0","event_id":"sha256:48f3db740d01d717a47e9d0657bfeb3af710e29b0e93949d47b857bd3bda0886"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2011:7AUEWOEFK4VDHYE52GW2ZO6U5F","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Insights into the mechanisms of electromediated gene delivery and application to the loading of giant vesicles with negatively charged macromolecules","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft","q-bio.SC"],"primary_cat":"physics.bio-ph","authors_text":"Cyril Favard, David S. Dean, Justin Teissi\\'e, Marie-Pierre Rols, Thomas Portet","submitted_at":"2011-02-03T07:38:18Z","abstract_excerpt":"We present experimental results regarding the electrotransfer of plasmid DNA into phosphatidylcholine giant unilamellar vesicles (GUVs). Our observations indicate that a direct entry is the predominant mechanism of electrotransfer. A quantitative analysis of the DNA concentration increments inside the GUVs is also performed, and we find that our experimental data are very well described by a simple theoretical model in which DNA entry is mostly driven by electrophoresis. Our theoretical framework allows for the prediction of the amount of transfered DNA as a function of the electric field para"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1102.0610","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:30:03Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"QpVZ3+A8Y/YenpRa6spcITvFlKfypWId2K2bfkFFZ7Gv8PDVg0ERI2MMJP3j6o/LzB07izRRq3GAlVfzgt9mDg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-11T10:13:50.142799Z"},"content_sha256":"87ad2c06ca091d29189609b9729b81fdbce0c3f54cec864040b3933fb885485d","schema_version":"1.0","event_id":"sha256:87ad2c06ca091d29189609b9729b81fdbce0c3f54cec864040b3933fb885485d"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/7AUEWOEFK4VDHYE52GW2ZO6U5F/bundle.json","state_url":"https://pith.science/pith/7AUEWOEFK4VDHYE52GW2ZO6U5F/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/7AUEWOEFK4VDHYE52GW2ZO6U5F/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-11T10:13:50Z","links":{"resolver":"https://pith.science/pith/7AUEWOEFK4VDHYE52GW2ZO6U5F","bundle":"https://pith.science/pith/7AUEWOEFK4VDHYE52GW2ZO6U5F/bundle.json","state":"https://pith.science/pith/7AUEWOEFK4VDHYE52GW2ZO6U5F/state.json","well_known_bundle":"https://pith.science/.well-known/pith/7AUEWOEFK4VDHYE52GW2ZO6U5F/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2011:7AUEWOEFK4VDHYE52GW2ZO6U5F","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"00b96a1086582c4c939dccc1d0508995c44fa027f68c7f7b70432fb9b0f08e3e","cross_cats_sorted":["cond-mat.soft","q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-02-03T07:38:18Z","title_canon_sha256":"790d534863dde733683c084637fecfe3ff7add9cc93be13aafaa22d3d3b00b92"},"schema_version":"1.0","source":{"id":"1102.0610","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1102.0610","created_at":"2026-05-18T04:30:03Z"},{"alias_kind":"arxiv_version","alias_value":"1102.0610v1","created_at":"2026-05-18T04:30:03Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1102.0610","created_at":"2026-05-18T04:30:03Z"},{"alias_kind":"pith_short_12","alias_value":"7AUEWOEFK4VD","created_at":"2026-05-18T12:26:22Z"},{"alias_kind":"pith_short_16","alias_value":"7AUEWOEFK4VDHYE5","created_at":"2026-05-18T12:26:22Z"},{"alias_kind":"pith_short_8","alias_value":"7AUEWOEF","created_at":"2026-05-18T12:26:22Z"}],"graph_snapshots":[{"event_id":"sha256:87ad2c06ca091d29189609b9729b81fdbce0c3f54cec864040b3933fb885485d","target":"graph","created_at":"2026-05-18T04:30:03Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"We present experimental results regarding the electrotransfer of plasmid DNA into phosphatidylcholine giant unilamellar vesicles (GUVs). Our observations indicate that a direct entry is the predominant mechanism of electrotransfer. A quantitative analysis of the DNA concentration increments inside the GUVs is also performed, and we find that our experimental data are very well described by a simple theoretical model in which DNA entry is mostly driven by electrophoresis. Our theoretical framework allows for the prediction of the amount of transfered DNA as a function of the electric field para","authors_text":"Cyril Favard, David S. Dean, Justin Teissi\\'e, Marie-Pierre Rols, Thomas Portet","cross_cats":["cond-mat.soft","q-bio.SC"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-02-03T07:38:18Z","title":"Insights into the mechanisms of electromediated gene delivery and application to the loading of giant vesicles with negatively charged macromolecules"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1102.0610","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:48f3db740d01d717a47e9d0657bfeb3af710e29b0e93949d47b857bd3bda0886","target":"record","created_at":"2026-05-18T04:30:03Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"00b96a1086582c4c939dccc1d0508995c44fa027f68c7f7b70432fb9b0f08e3e","cross_cats_sorted":["cond-mat.soft","q-bio.SC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-02-03T07:38:18Z","title_canon_sha256":"790d534863dde733683c084637fecfe3ff7add9cc93be13aafaa22d3d3b00b92"},"schema_version":"1.0","source":{"id":"1102.0610","kind":"arxiv","version":1}},"canonical_sha256":"f8284b3885572a33e09dd1adacbbd4e94f313475db95f733abca2084fd3aba8b","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"f8284b3885572a33e09dd1adacbbd4e94f313475db95f733abca2084fd3aba8b","first_computed_at":"2026-05-18T04:30:03.616293Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T04:30:03.616293Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"SsSi2nCCXU5vYGlvxoZ/TApm+3J9CTh/j5CQ7SFk6zY2yC8aywIb0hmfjWyLfSShavV7cfopf1GovnWxoY57Ag==","signature_status":"signed_v1","signed_at":"2026-05-18T04:30:03.616695Z","signed_message":"canonical_sha256_bytes"},"source_id":"1102.0610","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:48f3db740d01d717a47e9d0657bfeb3af710e29b0e93949d47b857bd3bda0886","sha256:87ad2c06ca091d29189609b9729b81fdbce0c3f54cec864040b3933fb885485d"],"state_sha256":"8dd484ff86087a45a7fd2dcebabf91bfbdbb75266fbc53d171216ec643242df2"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"zzne4OYq6howvXmSaZgT3K49e+ur1EOeK8Wk6u0dchCrqeTpaK6xDyvGfMxEgSj9QhAYi/T59vagskKlAXfZBA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-11T10:13:50.144996Z","bundle_sha256":"61f1f28dedf892ac4fb250d72002710b34334b690e2406ef53774cc650e4b08f"}}