{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:7HOK5R54RZI6IN4XRE52NWBTWN","short_pith_number":"pith:7HOK5R54","canonical_record":{"source":{"id":"1801.07318","kind":"arxiv","version":3},"metadata":{"license":"http://creativecommons.org/licenses/by-sa/4.0/","primary_cat":"stat.ME","submitted_at":"2018-01-22T20:57:39Z","cross_cats_sorted":["q-bio.QM","stat.AP","stat.ML"],"title_canon_sha256":"9add360111fbb6b936a24a5f5073fc05a6c708676fa7cc79ba7c76ba538198fd","abstract_canon_sha256":"3df30a6b212ac7eb2dac03e81d4a9ae5e6916bb121510a08cc96c6b8df31419d"},"schema_version":"1.0"},"canonical_sha256":"f9dcaec7bc8e51e43797893ba6d833b375686993135112758ac6c32b482111f2","source":{"kind":"arxiv","id":"1801.07318","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1801.07318","created_at":"2026-05-18T00:07:18Z"},{"alias_kind":"arxiv_version","alias_value":"1801.07318v3","created_at":"2026-05-18T00:07:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1801.07318","created_at":"2026-05-18T00:07:18Z"},{"alias_kind":"pith_short_12","alias_value":"7HOK5R54RZI6","created_at":"2026-05-18T12:32:11Z"},{"alias_kind":"pith_short_16","alias_value":"7HOK5R54RZI6IN4X","created_at":"2026-05-18T12:32:11Z"},{"alias_kind":"pith_short_8","alias_value":"7HOK5R54","created_at":"2026-05-18T12:32:11Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:7HOK5R54RZI6IN4XRE52NWBTWN","target":"record","payload":{"canonical_record":{"source":{"id":"1801.07318","kind":"arxiv","version":3},"metadata":{"license":"http://creativecommons.org/licenses/by-sa/4.0/","primary_cat":"stat.ME","submitted_at":"2018-01-22T20:57:39Z","cross_cats_sorted":["q-bio.QM","stat.AP","stat.ML"],"title_canon_sha256":"9add360111fbb6b936a24a5f5073fc05a6c708676fa7cc79ba7c76ba538198fd","abstract_canon_sha256":"3df30a6b212ac7eb2dac03e81d4a9ae5e6916bb121510a08cc96c6b8df31419d"},"schema_version":"1.0"},"canonical_sha256":"f9dcaec7bc8e51e43797893ba6d833b375686993135112758ac6c32b482111f2","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:07:18.037193Z","signature_b64":"G1cAJ6WJ7tnE7gG5wBXNe7j2YhU7XWpv7CgsDbEZIp6p91B14JgNHmfhYHDGmrJX2PJFhQPy5HnY1X+jNh0JAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"f9dcaec7bc8e51e43797893ba6d833b375686993135112758ac6c32b482111f2","last_reissued_at":"2026-05-18T00:07:18.036555Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:07:18.036555Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1801.07318","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:07:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"700uDnqIbf5uHLnfEnKkW93ECLy+dBJ4gUHy3xX/FQYMgRqpwEpkxEX++Dh09duDPiV3RYGFhIy9zcYRs9lPAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-09T16:01:12.354588Z"},"content_sha256":"c870a7445ebee0f629f634214eccedd1cbc40c4cc5020098f00f159e9e32ebef","schema_version":"1.0","event_id":"sha256:c870a7445ebee0f629f634214eccedd1cbc40c4cc5020098f00f159e9e32ebef"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:7HOK5R54RZI6IN4XRE52NWBTWN","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Variable Prioritization in Nonlinear Black Box Methods: A Genetic Association Case Study","license":"http://creativecommons.org/licenses/by-sa/4.0/","headline":"","cross_cats":["q-bio.QM","stat.AP","stat.ML"],"primary_cat":"stat.ME","authors_text":"Daniel E. Runcie, Lorin Crawford, Mike West, Seth R. Flaxman","submitted_at":"2018-01-22T20:57:39Z","abstract_excerpt":"The central aim in this paper is to address variable selection questions in nonlinear and nonparametric regression. Motivated by statistical genetics, where nonlinear interactions are of particular interest, we introduce a novel and interpretable way to summarize the relative importance of predictor variables. Methodologically, we develop the \"RelATive cEntrality\" (RATE) measure to prioritize candidate genetic variants that are not just marginally important, but whose associations also stem from significant covarying relationships with other variants in the data. We illustrate RATE through Bay"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1801.07318","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:07:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"tjPSEfoijhGWDNBX4mgKqoZ4gaNtMklOPhoYr5DQiOhSdwhoEGFg/ys2N/cFw2k/FZKpUhqbjZnVdoYrfKlSCw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-09T16:01:12.354934Z"},"content_sha256":"f62862214fe1d93b5bace1bde5f294c42a80efc0a3621dac05fa1915ce2d9319","schema_version":"1.0","event_id":"sha256:f62862214fe1d93b5bace1bde5f294c42a80efc0a3621dac05fa1915ce2d9319"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/7HOK5R54RZI6IN4XRE52NWBTWN/bundle.json","state_url":"https://pith.science/pith/7HOK5R54RZI6IN4XRE52NWBTWN/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/7HOK5R54RZI6IN4XRE52NWBTWN/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-09T16:01:12Z","links":{"resolver":"https://pith.science/pith/7HOK5R54RZI6IN4XRE52NWBTWN","bundle":"https://pith.science/pith/7HOK5R54RZI6IN4XRE52NWBTWN/bundle.json","state":"https://pith.science/pith/7HOK5R54RZI6IN4XRE52NWBTWN/state.json","well_known_bundle":"https://pith.science/.well-known/pith/7HOK5R54RZI6IN4XRE52NWBTWN/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:7HOK5R54RZI6IN4XRE52NWBTWN","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"3df30a6b212ac7eb2dac03e81d4a9ae5e6916bb121510a08cc96c6b8df31419d","cross_cats_sorted":["q-bio.QM","stat.AP","stat.ML"],"license":"http://creativecommons.org/licenses/by-sa/4.0/","primary_cat":"stat.ME","submitted_at":"2018-01-22T20:57:39Z","title_canon_sha256":"9add360111fbb6b936a24a5f5073fc05a6c708676fa7cc79ba7c76ba538198fd"},"schema_version":"1.0","source":{"id":"1801.07318","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1801.07318","created_at":"2026-05-18T00:07:18Z"},{"alias_kind":"arxiv_version","alias_value":"1801.07318v3","created_at":"2026-05-18T00:07:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1801.07318","created_at":"2026-05-18T00:07:18Z"},{"alias_kind":"pith_short_12","alias_value":"7HOK5R54RZI6","created_at":"2026-05-18T12:32:11Z"},{"alias_kind":"pith_short_16","alias_value":"7HOK5R54RZI6IN4X","created_at":"2026-05-18T12:32:11Z"},{"alias_kind":"pith_short_8","alias_value":"7HOK5R54","created_at":"2026-05-18T12:32:11Z"}],"graph_snapshots":[{"event_id":"sha256:f62862214fe1d93b5bace1bde5f294c42a80efc0a3621dac05fa1915ce2d9319","target":"graph","created_at":"2026-05-18T00:07:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The central aim in this paper is to address variable selection questions in nonlinear and nonparametric regression. Motivated by statistical genetics, where nonlinear interactions are of particular interest, we introduce a novel and interpretable way to summarize the relative importance of predictor variables. Methodologically, we develop the \"RelATive cEntrality\" (RATE) measure to prioritize candidate genetic variants that are not just marginally important, but whose associations also stem from significant covarying relationships with other variants in the data. We illustrate RATE through Bay","authors_text":"Daniel E. Runcie, Lorin Crawford, Mike West, Seth R. Flaxman","cross_cats":["q-bio.QM","stat.AP","stat.ML"],"headline":"","license":"http://creativecommons.org/licenses/by-sa/4.0/","primary_cat":"stat.ME","submitted_at":"2018-01-22T20:57:39Z","title":"Variable Prioritization in Nonlinear Black Box Methods: A Genetic Association Case Study"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1801.07318","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:c870a7445ebee0f629f634214eccedd1cbc40c4cc5020098f00f159e9e32ebef","target":"record","created_at":"2026-05-18T00:07:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"3df30a6b212ac7eb2dac03e81d4a9ae5e6916bb121510a08cc96c6b8df31419d","cross_cats_sorted":["q-bio.QM","stat.AP","stat.ML"],"license":"http://creativecommons.org/licenses/by-sa/4.0/","primary_cat":"stat.ME","submitted_at":"2018-01-22T20:57:39Z","title_canon_sha256":"9add360111fbb6b936a24a5f5073fc05a6c708676fa7cc79ba7c76ba538198fd"},"schema_version":"1.0","source":{"id":"1801.07318","kind":"arxiv","version":3}},"canonical_sha256":"f9dcaec7bc8e51e43797893ba6d833b375686993135112758ac6c32b482111f2","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"f9dcaec7bc8e51e43797893ba6d833b375686993135112758ac6c32b482111f2","first_computed_at":"2026-05-18T00:07:18.036555Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:07:18.036555Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"G1cAJ6WJ7tnE7gG5wBXNe7j2YhU7XWpv7CgsDbEZIp6p91B14JgNHmfhYHDGmrJX2PJFhQPy5HnY1X+jNh0JAg==","signature_status":"signed_v1","signed_at":"2026-05-18T00:07:18.037193Z","signed_message":"canonical_sha256_bytes"},"source_id":"1801.07318","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:c870a7445ebee0f629f634214eccedd1cbc40c4cc5020098f00f159e9e32ebef","sha256:f62862214fe1d93b5bace1bde5f294c42a80efc0a3621dac05fa1915ce2d9319"],"state_sha256":"76350c31fce751610c7e43d7d2a9fc66a112ae21c9e9a8288c70b7df65456278"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"KTP9S/M7LThuXzAfd9W+Uo+xVwxB8oHn9O89yCjLUX1nmBE8dCjkmlgtKgij9/Cr9Whb8fDv8xhSZJ0BC9W2DA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-09T16:01:12.356908Z","bundle_sha256":"7f6d93b8390abeaaae5dde05b08b8c7fc12aac13de54ee5f6e72310fcff8c55b"}}