{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:7KGOHN4ONE27BANMGGHN3GDYCJ","short_pith_number":"pith:7KGOHN4O","canonical_record":{"source":{"id":"1909.07581","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2019-09-17T04:32:09Z","cross_cats_sorted":["cs.CV"],"title_canon_sha256":"020732d44d6a912e884cd7dd65bf6d9fc0fc05e09506e3697db76ec06749a798","abstract_canon_sha256":"5093aea42898e89c7f20f205b88ef87f6cf44bb165af3dc7e70698ad7b2d2c00"},"schema_version":"1.0"},"canonical_sha256":"fa8ce3b78e6935f081ac318edd9878125d4aa082aac9a77b5d799d00b6630afb","source":{"kind":"arxiv","id":"1909.07581","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1909.07581","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"arxiv_version","alias_value":"1909.07581v2","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1909.07581","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"pith_short_12","alias_value":"7KGOHN4ONE27","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"pith_short_16","alias_value":"7KGOHN4ONE27BANM","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"pith_short_8","alias_value":"7KGOHN4O","created_at":"2026-07-05T00:05:46Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:7KGOHN4ONE27BANMGGHN3GDYCJ","target":"record","payload":{"canonical_record":{"source":{"id":"1909.07581","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2019-09-17T04:32:09Z","cross_cats_sorted":["cs.CV"],"title_canon_sha256":"020732d44d6a912e884cd7dd65bf6d9fc0fc05e09506e3697db76ec06749a798","abstract_canon_sha256":"5093aea42898e89c7f20f205b88ef87f6cf44bb165af3dc7e70698ad7b2d2c00"},"schema_version":"1.0"},"canonical_sha256":"fa8ce3b78e6935f081ac318edd9878125d4aa082aac9a77b5d799d00b6630afb","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T00:05:46.204058Z","signature_b64":"7EzztECtXUmfdeDQHFOgTxfdBMRN1wEanpv+KY1+lLj9luAHs2+m3W3kmXqJSUN5vC12T8vXjDRpB4WeYxxACQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"fa8ce3b78e6935f081ac318edd9878125d4aa082aac9a77b5d799d00b6630afb","last_reissued_at":"2026-07-05T00:05:46.203602Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T00:05:46.203602Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1909.07581","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T00:05:46Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"95rYZ748FIhgOGQptFhDDdXraMyYafRdNFiNhUx0M5VyqFsPeLDsORuC26wwHDnKpEicBXMwx6iHPHwS9AdUDg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-19T23:33:45.176907Z"},"content_sha256":"1e9debbd63be6eb108377a4d2b934325bee5e1c7fa8d4e54a9d34305ce029d94","schema_version":"1.0","event_id":"sha256:1e9debbd63be6eb108377a4d2b934325bee5e1c7fa8d4e54a9d34305ce029d94"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:7KGOHN4ONE27BANMGGHN3GDYCJ","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Radiopathomics: Integration of radiographic and histologic characteristics for prognostication in glioblastoma","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.CV"],"primary_cat":"eess.IV","authors_text":"Metin N. Gurcan, Muhammad A. Iftikhar, Saima Rathore, Zissimos Mourelatos","submitted_at":"2019-09-17T04:32:09Z","abstract_excerpt":"Both radiographic (Rad) imaging, such as multi-parametric magnetic resonance imaging, and digital pathology (Path) images captured from tissue samples are currently acquired as standard clinical practice for glioblastoma tumors. Both these data streams have been separately used for diagnosis and treatment planning, despite the fact that they provide complementary information. In this research work, we aimed to assess the potential of both Rad and Path images in combination and comparison. An extensive set of engineered features was extracted from delineated tumor regions in Rad images, compris"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1909.07581","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/1909.07581/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T00:05:46Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"/LUBmSt/q4JOOmxDnvJn6pcA45TbH1SxJNQdeIV4Wcw8b56Wa0t8Ja1vmJy9j3EyCbgV9cSBQBIrMQA3KKzfAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-19T23:33:45.177844Z"},"content_sha256":"2c81e50e4bc0248fc5a7a64e22406762493065c91eb1778011e13d092ee97c43","schema_version":"1.0","event_id":"sha256:2c81e50e4bc0248fc5a7a64e22406762493065c91eb1778011e13d092ee97c43"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/7KGOHN4ONE27BANMGGHN3GDYCJ/bundle.json","state_url":"https://pith.science/pith/7KGOHN4ONE27BANMGGHN3GDYCJ/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/7KGOHN4ONE27BANMGGHN3GDYCJ/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-19T23:33:45Z","links":{"resolver":"https://pith.science/pith/7KGOHN4ONE27BANMGGHN3GDYCJ","bundle":"https://pith.science/pith/7KGOHN4ONE27BANMGGHN3GDYCJ/bundle.json","state":"https://pith.science/pith/7KGOHN4ONE27BANMGGHN3GDYCJ/state.json","well_known_bundle":"https://pith.science/.well-known/pith/7KGOHN4ONE27BANMGGHN3GDYCJ/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:7KGOHN4ONE27BANMGGHN3GDYCJ","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"5093aea42898e89c7f20f205b88ef87f6cf44bb165af3dc7e70698ad7b2d2c00","cross_cats_sorted":["cs.CV"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2019-09-17T04:32:09Z","title_canon_sha256":"020732d44d6a912e884cd7dd65bf6d9fc0fc05e09506e3697db76ec06749a798"},"schema_version":"1.0","source":{"id":"1909.07581","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1909.07581","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"arxiv_version","alias_value":"1909.07581v2","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1909.07581","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"pith_short_12","alias_value":"7KGOHN4ONE27","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"pith_short_16","alias_value":"7KGOHN4ONE27BANM","created_at":"2026-07-05T00:05:46Z"},{"alias_kind":"pith_short_8","alias_value":"7KGOHN4O","created_at":"2026-07-05T00:05:46Z"}],"graph_snapshots":[{"event_id":"sha256:2c81e50e4bc0248fc5a7a64e22406762493065c91eb1778011e13d092ee97c43","target":"graph","created_at":"2026-07-05T00:05:46Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/1909.07581/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Both radiographic (Rad) imaging, such as multi-parametric magnetic resonance imaging, and digital pathology (Path) images captured from tissue samples are currently acquired as standard clinical practice for glioblastoma tumors. Both these data streams have been separately used for diagnosis and treatment planning, despite the fact that they provide complementary information. In this research work, we aimed to assess the potential of both Rad and Path images in combination and comparison. An extensive set of engineered features was extracted from delineated tumor regions in Rad images, compris","authors_text":"Metin N. Gurcan, Muhammad A. Iftikhar, Saima Rathore, Zissimos Mourelatos","cross_cats":["cs.CV"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2019-09-17T04:32:09Z","title":"Radiopathomics: Integration of radiographic and histologic characteristics for prognostication in glioblastoma"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1909.07581","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:1e9debbd63be6eb108377a4d2b934325bee5e1c7fa8d4e54a9d34305ce029d94","target":"record","created_at":"2026-07-05T00:05:46Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"5093aea42898e89c7f20f205b88ef87f6cf44bb165af3dc7e70698ad7b2d2c00","cross_cats_sorted":["cs.CV"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2019-09-17T04:32:09Z","title_canon_sha256":"020732d44d6a912e884cd7dd65bf6d9fc0fc05e09506e3697db76ec06749a798"},"schema_version":"1.0","source":{"id":"1909.07581","kind":"arxiv","version":2}},"canonical_sha256":"fa8ce3b78e6935f081ac318edd9878125d4aa082aac9a77b5d799d00b6630afb","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"fa8ce3b78e6935f081ac318edd9878125d4aa082aac9a77b5d799d00b6630afb","first_computed_at":"2026-07-05T00:05:46.203602Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T00:05:46.203602Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"7EzztECtXUmfdeDQHFOgTxfdBMRN1wEanpv+KY1+lLj9luAHs2+m3W3kmXqJSUN5vC12T8vXjDRpB4WeYxxACQ==","signature_status":"signed_v1","signed_at":"2026-07-05T00:05:46.204058Z","signed_message":"canonical_sha256_bytes"},"source_id":"1909.07581","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:1e9debbd63be6eb108377a4d2b934325bee5e1c7fa8d4e54a9d34305ce029d94","sha256:2c81e50e4bc0248fc5a7a64e22406762493065c91eb1778011e13d092ee97c43"],"state_sha256":"0e7a2959bee2d17d27af7e83e0ee5e5042ea8cb867a5b65aefbdb9920356ad32"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"2ecAPA74x08pTfyTriHv5g8dwygYzx2HcZ5x02D+wF+oY+PUdmWwhxkQASvfyi2SwzZRG3jJk4AB0Cy0bfnFDQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-19T23:33:45.183874Z","bundle_sha256":"69f0d2d1c8c03cf7939009ae44d54202f7d61d9e25fc727bc505547a0de99b24"}}