{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2015:7KVEFBAEJGPRYQUQIUOPYP54L4","short_pith_number":"pith:7KVEFBAE","schema_version":"1.0","canonical_sha256":"faaa428404499f1c4290451cfc3fbc5f047b68343971594cc51150cbbe3d534a","source":{"kind":"arxiv","id":"1510.02940","version":1},"attestation_state":"computed","paper":{"title":"Thermodynamic Free Energy Methods to Investigate Shape Transitions In Bilayer Membranes","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft","cond-mat.stat-mech"],"primary_cat":"physics.bio-ph","authors_text":"N. Ramakrishnan, Ravi Radhakrishnan, Richard W. Tourdot","submitted_at":"2015-10-10T14:12:08Z","abstract_excerpt":"The conformational free energy landscape of a system is a fundamental thermodynamic quantity of importance particularly in the study of soft matter and biological systems, in which the entropic contributions play a dominant role. While computational methods to delineate the free energy landscape are routinely used to analyze the relative stability of conformational states, to determine phase boundaries, and to compute ligand-receptor binding energies its use in problems involving the cell membrane is limited. Here, we present an overview of four different free energy methods to study morpholog"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1510.02940","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-10-10T14:12:08Z","cross_cats_sorted":["cond-mat.soft","cond-mat.stat-mech"],"title_canon_sha256":"bad2d108652a1375f73a9b59eaeef90f6b8baaa5ab0d6748fce52c41b8022136","abstract_canon_sha256":"8b48ce4cbcee7c38b87ad1024d27cabd92127065a0520429361afa4009691689"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:30:33.248192Z","signature_b64":"eV4x+q+rd5Q/qj/FoXgVQY2+FSNImyr2ZJ+ikcR94ULs5EYsVgstvJkd+TALjqSuT/tMVNKCy4r9I3cQKXFjBQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"faaa428404499f1c4290451cfc3fbc5f047b68343971594cc51150cbbe3d534a","last_reissued_at":"2026-05-18T01:30:33.247485Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:30:33.247485Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Thermodynamic Free Energy Methods to Investigate Shape Transitions In Bilayer Membranes","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft","cond-mat.stat-mech"],"primary_cat":"physics.bio-ph","authors_text":"N. Ramakrishnan, Ravi Radhakrishnan, Richard W. Tourdot","submitted_at":"2015-10-10T14:12:08Z","abstract_excerpt":"The conformational free energy landscape of a system is a fundamental thermodynamic quantity of importance particularly in the study of soft matter and biological systems, in which the entropic contributions play a dominant role. While computational methods to delineate the free energy landscape are routinely used to analyze the relative stability of conformational states, to determine phase boundaries, and to compute ligand-receptor binding energies its use in problems involving the cell membrane is limited. Here, we present an overview of four different free energy methods to study morpholog"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1510.02940","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1510.02940","created_at":"2026-05-18T01:30:33.247586+00:00"},{"alias_kind":"arxiv_version","alias_value":"1510.02940v1","created_at":"2026-05-18T01:30:33.247586+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1510.02940","created_at":"2026-05-18T01:30:33.247586+00:00"},{"alias_kind":"pith_short_12","alias_value":"7KVEFBAEJGPR","created_at":"2026-05-18T12:29:10.953037+00:00"},{"alias_kind":"pith_short_16","alias_value":"7KVEFBAEJGPRYQUQ","created_at":"2026-05-18T12:29:10.953037+00:00"},{"alias_kind":"pith_short_8","alias_value":"7KVEFBAE","created_at":"2026-05-18T12:29:10.953037+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/7KVEFBAEJGPRYQUQIUOPYP54L4","json":"https://pith.science/pith/7KVEFBAEJGPRYQUQIUOPYP54L4.json","graph_json":"https://pith.science/api/pith-number/7KVEFBAEJGPRYQUQIUOPYP54L4/graph.json","events_json":"https://pith.science/api/pith-number/7KVEFBAEJGPRYQUQIUOPYP54L4/events.json","paper":"https://pith.science/paper/7KVEFBAE"},"agent_actions":{"view_html":"https://pith.science/pith/7KVEFBAEJGPRYQUQIUOPYP54L4","download_json":"https://pith.science/pith/7KVEFBAEJGPRYQUQIUOPYP54L4.json","view_paper":"https://pith.science/paper/7KVEFBAE","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1510.02940&json=true","fetch_graph":"https://pith.science/api/pith-number/7KVEFBAEJGPRYQUQIUOPYP54L4/graph.json","fetch_events":"https://pith.science/api/pith-number/7KVEFBAEJGPRYQUQIUOPYP54L4/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/7KVEFBAEJGPRYQUQIUOPYP54L4/action/timestamp_anchor","attest_storage":"https://pith.science/pith/7KVEFBAEJGPRYQUQIUOPYP54L4/action/storage_attestation","attest_author":"https://pith.science/pith/7KVEFBAEJGPRYQUQIUOPYP54L4/action/author_attestation","sign_citation":"https://pith.science/pith/7KVEFBAEJGPRYQUQIUOPYP54L4/action/citation_signature","submit_replication":"https://pith.science/pith/7KVEFBAEJGPRYQUQIUOPYP54L4/action/replication_record"}},"created_at":"2026-05-18T01:30:33.247586+00:00","updated_at":"2026-05-18T01:30:33.247586+00:00"}