{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:A37F2B3GYH7IY6AH4FN3ZLGKO4","short_pith_number":"pith:A37F2B3G","canonical_record":{"source":{"id":"1605.00688","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.flu-dyn","submitted_at":"2016-05-02T21:02:59Z","cross_cats_sorted":[],"title_canon_sha256":"d67b11a1670275cd6eff339f1f33b095e88361a5f6d67e5f88f732011ac97a97","abstract_canon_sha256":"0fc18b57e1124b94923fa4ed0079db35f361f92fae63a5048307b3f55d79eb88"},"schema_version":"1.0"},"canonical_sha256":"06fe5d0766c1fe8c7807e15bbcacca7717afb4d82409ef296c4ad83545e85ad6","source":{"kind":"arxiv","id":"1605.00688","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1605.00688","created_at":"2026-05-18T01:12:40Z"},{"alias_kind":"arxiv_version","alias_value":"1605.00688v2","created_at":"2026-05-18T01:12:40Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1605.00688","created_at":"2026-05-18T01:12:40Z"},{"alias_kind":"pith_short_12","alias_value":"A37F2B3GYH7I","created_at":"2026-05-18T12:30:04Z"},{"alias_kind":"pith_short_16","alias_value":"A37F2B3GYH7IY6AH","created_at":"2026-05-18T12:30:04Z"},{"alias_kind":"pith_short_8","alias_value":"A37F2B3G","created_at":"2026-05-18T12:30:04Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:A37F2B3GYH7IY6AH4FN3ZLGKO4","target":"record","payload":{"canonical_record":{"source":{"id":"1605.00688","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.flu-dyn","submitted_at":"2016-05-02T21:02:59Z","cross_cats_sorted":[],"title_canon_sha256":"d67b11a1670275cd6eff339f1f33b095e88361a5f6d67e5f88f732011ac97a97","abstract_canon_sha256":"0fc18b57e1124b94923fa4ed0079db35f361f92fae63a5048307b3f55d79eb88"},"schema_version":"1.0"},"canonical_sha256":"06fe5d0766c1fe8c7807e15bbcacca7717afb4d82409ef296c4ad83545e85ad6","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:12:40.201400Z","signature_b64":"dShgXT0P5F6Ii32Bn80nd+I5rfD6ox1hOav9CuuOiZDk4Kqg2aG3gnMeHws/0IPO3oMKmdEm0y6fyDZ54R/oCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"06fe5d0766c1fe8c7807e15bbcacca7717afb4d82409ef296c4ad83545e85ad6","last_reissued_at":"2026-05-18T01:12:40.201039Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:12:40.201039Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1605.00688","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:12:40Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"SLhVRxOPlsc9O1zvYuuRW+hGvJY/DnkvKZZ6vItyiiiFSf1K6uwwXT3ec0r2NpI/ub3NH+4I/KOpiu54iJ8AAQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T03:53:38.245592Z"},"content_sha256":"dc14eaa8db6a4ae38a6ef5957d29cb4a10a4be2e3c0e82bbd8bc5577c79e6c43","schema_version":"1.0","event_id":"sha256:dc14eaa8db6a4ae38a6ef5957d29cb4a10a4be2e3c0e82bbd8bc5577c79e6c43"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:A37F2B3GYH7IY6AH4FN3ZLGKO4","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Mucociliary Transport in Healthy and Diseased Environments","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.flu-dyn","authors_text":"Eva Kanso, Hanliang Guo","submitted_at":"2016-05-02T21:02:59Z","abstract_excerpt":"Mucociliary clearance in the lung is the primary defense mechanism that protects the airways from inhaled toxicants and infectious agents. The system consists of a viscoelastic mucus layer driven by motile cilia in a periciliary layer underneath the mucus layer. Under healthy conditions, the thickness of the periciliary layer is comparable to cilia length. Perturbations to this system, whether due to a genetic disorder or acquired causes, are directly linked to infection and disease. For example, depletion of the periciliary layer is typically observed in diseases such as chronic obstructive p"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1605.00688","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:12:40Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"s/4n4/9pJo+bn4Da5+iB9jDXqcg2gZGZWraUAKLOMKXODqoamGMCvgFo2CpMhgY6WuKiuzgWQqoZN0L9gXxIAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T03:53:38.246204Z"},"content_sha256":"dce5fe46fc41ba183f1a44a2ed2f22bade9aa54a3fb9193da87d968ce45ec70c","schema_version":"1.0","event_id":"sha256:dce5fe46fc41ba183f1a44a2ed2f22bade9aa54a3fb9193da87d968ce45ec70c"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/A37F2B3GYH7IY6AH4FN3ZLGKO4/bundle.json","state_url":"https://pith.science/pith/A37F2B3GYH7IY6AH4FN3ZLGKO4/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/A37F2B3GYH7IY6AH4FN3ZLGKO4/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T03:53:38Z","links":{"resolver":"https://pith.science/pith/A37F2B3GYH7IY6AH4FN3ZLGKO4","bundle":"https://pith.science/pith/A37F2B3GYH7IY6AH4FN3ZLGKO4/bundle.json","state":"https://pith.science/pith/A37F2B3GYH7IY6AH4FN3ZLGKO4/state.json","well_known_bundle":"https://pith.science/.well-known/pith/A37F2B3GYH7IY6AH4FN3ZLGKO4/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:A37F2B3GYH7IY6AH4FN3ZLGKO4","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"0fc18b57e1124b94923fa4ed0079db35f361f92fae63a5048307b3f55d79eb88","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.flu-dyn","submitted_at":"2016-05-02T21:02:59Z","title_canon_sha256":"d67b11a1670275cd6eff339f1f33b095e88361a5f6d67e5f88f732011ac97a97"},"schema_version":"1.0","source":{"id":"1605.00688","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1605.00688","created_at":"2026-05-18T01:12:40Z"},{"alias_kind":"arxiv_version","alias_value":"1605.00688v2","created_at":"2026-05-18T01:12:40Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1605.00688","created_at":"2026-05-18T01:12:40Z"},{"alias_kind":"pith_short_12","alias_value":"A37F2B3GYH7I","created_at":"2026-05-18T12:30:04Z"},{"alias_kind":"pith_short_16","alias_value":"A37F2B3GYH7IY6AH","created_at":"2026-05-18T12:30:04Z"},{"alias_kind":"pith_short_8","alias_value":"A37F2B3G","created_at":"2026-05-18T12:30:04Z"}],"graph_snapshots":[{"event_id":"sha256:dce5fe46fc41ba183f1a44a2ed2f22bade9aa54a3fb9193da87d968ce45ec70c","target":"graph","created_at":"2026-05-18T01:12:40Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Mucociliary clearance in the lung is the primary defense mechanism that protects the airways from inhaled toxicants and infectious agents. The system consists of a viscoelastic mucus layer driven by motile cilia in a periciliary layer underneath the mucus layer. Under healthy conditions, the thickness of the periciliary layer is comparable to cilia length. Perturbations to this system, whether due to a genetic disorder or acquired causes, are directly linked to infection and disease. For example, depletion of the periciliary layer is typically observed in diseases such as chronic obstructive p","authors_text":"Eva Kanso, Hanliang Guo","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.flu-dyn","submitted_at":"2016-05-02T21:02:59Z","title":"Mucociliary Transport in Healthy and Diseased Environments"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1605.00688","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:dc14eaa8db6a4ae38a6ef5957d29cb4a10a4be2e3c0e82bbd8bc5577c79e6c43","target":"record","created_at":"2026-05-18T01:12:40Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"0fc18b57e1124b94923fa4ed0079db35f361f92fae63a5048307b3f55d79eb88","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.flu-dyn","submitted_at":"2016-05-02T21:02:59Z","title_canon_sha256":"d67b11a1670275cd6eff339f1f33b095e88361a5f6d67e5f88f732011ac97a97"},"schema_version":"1.0","source":{"id":"1605.00688","kind":"arxiv","version":2}},"canonical_sha256":"06fe5d0766c1fe8c7807e15bbcacca7717afb4d82409ef296c4ad83545e85ad6","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"06fe5d0766c1fe8c7807e15bbcacca7717afb4d82409ef296c4ad83545e85ad6","first_computed_at":"2026-05-18T01:12:40.201039Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:12:40.201039Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"dShgXT0P5F6Ii32Bn80nd+I5rfD6ox1hOav9CuuOiZDk4Kqg2aG3gnMeHws/0IPO3oMKmdEm0y6fyDZ54R/oCA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:12:40.201400Z","signed_message":"canonical_sha256_bytes"},"source_id":"1605.00688","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:dc14eaa8db6a4ae38a6ef5957d29cb4a10a4be2e3c0e82bbd8bc5577c79e6c43","sha256:dce5fe46fc41ba183f1a44a2ed2f22bade9aa54a3fb9193da87d968ce45ec70c"],"state_sha256":"fc937849358f02b311b3f645caef6e76e2e7ad53eb7bb9f69e72cdf8998d8575"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"aiHCbtWWh0MK9PXVz4JqwkHjnCKI3uyCnTRWEeR0ualCvtOGSjm1uVmFpRVPLvg/q9xFGlf69o9GBfmS5SIfBA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T03:53:38.249495Z","bundle_sha256":"d9ab611a36e0d796b1abdc99e26f08b3b1f8af5ca313fff24cfc1d761335214f"}}