{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:A6KQI6NISVJRNPZ5LS4E6WJ7KV","short_pith_number":"pith:A6KQI6NI","canonical_record":{"source":{"id":"1610.10021","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-10-31T17:14:47Z","cross_cats_sorted":["physics.bio-ph"],"title_canon_sha256":"540440fdc4c148f7dd9f4058a6d60ff8bb42d1b91232591ca238a3398aa20da1","abstract_canon_sha256":"8e75cfe0a27892faa1ef8e19a74f8fcb7398a192e22d321fe71f29ff47bbc049"},"schema_version":"1.0"},"canonical_sha256":"07950479a8955316bf3d5cb84f593f55610a7310108b9bec53ac836becdbd538","source":{"kind":"arxiv","id":"1610.10021","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1610.10021","created_at":"2026-05-18T01:00:46Z"},{"alias_kind":"arxiv_version","alias_value":"1610.10021v1","created_at":"2026-05-18T01:00:46Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1610.10021","created_at":"2026-05-18T01:00:46Z"},{"alias_kind":"pith_short_12","alias_value":"A6KQI6NISVJR","created_at":"2026-05-18T12:30:04Z"},{"alias_kind":"pith_short_16","alias_value":"A6KQI6NISVJRNPZ5","created_at":"2026-05-18T12:30:04Z"},{"alias_kind":"pith_short_8","alias_value":"A6KQI6NI","created_at":"2026-05-18T12:30:04Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:A6KQI6NISVJRNPZ5LS4E6WJ7KV","target":"record","payload":{"canonical_record":{"source":{"id":"1610.10021","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-10-31T17:14:47Z","cross_cats_sorted":["physics.bio-ph"],"title_canon_sha256":"540440fdc4c148f7dd9f4058a6d60ff8bb42d1b91232591ca238a3398aa20da1","abstract_canon_sha256":"8e75cfe0a27892faa1ef8e19a74f8fcb7398a192e22d321fe71f29ff47bbc049"},"schema_version":"1.0"},"canonical_sha256":"07950479a8955316bf3d5cb84f593f55610a7310108b9bec53ac836becdbd538","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:00:46.721685Z","signature_b64":"1shbPm8LQMFax8CFoTTljONxIDcJfEtVMVgsjsto9ydDHRCjA4jLJcapyOJQDfDK0y+xm61u3vt7R3XHFQiwAA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"07950479a8955316bf3d5cb84f593f55610a7310108b9bec53ac836becdbd538","last_reissued_at":"2026-05-18T01:00:46.721196Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:00:46.721196Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1610.10021","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:00:46Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"hqkgaGqEih5hZjCcDiW8HqvDHmoCIwX1ZMubLLvF6JMddi+JlGorwuBy6xyVLgEUT93pMApPNRdKLMt7nXqkBg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-03T03:12:52.060059Z"},"content_sha256":"0d7fc7e3c5306fb2147db8f4a16d1da741c23ac706d15e8eb03214923b8ac573","schema_version":"1.0","event_id":"sha256:0d7fc7e3c5306fb2147db8f4a16d1da741c23ac706d15e8eb03214923b8ac573"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:A6KQI6NISVJRNPZ5LS4E6WJ7KV","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Computed Flow and Fluorescence Over the Ocular Surface","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph"],"primary_cat":"q-bio.QM","authors_text":"Longfei Li, P. E. King-Smith, R. J. Braun, W. D. Henshaw","submitted_at":"2016-10-31T17:14:47Z","abstract_excerpt":"Fluorescein is perhaps the most commonly used substance to visualize tear film thickness and dynamics; better understanding of this process aids understanding of dry eye syndrome which afflicts millions of people. We study a mathematical model for tear film flow, evaporation, solutal transport and fluorescence over the exposed ocular surface during the interblink. Transport of the fluorescein ion by fluid flow in the tear film affects the intensity of fluorescence via changes in concentration and tear film thickness. Evaporation causes increased osmolarity and potential irritation over the ocu"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1610.10021","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:00:46Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"nMEjJJtrXPbUnkDKK10VaxIe0gpKQDsSL0J4k3JngXnAdEPL06AOx4k1xq0dc6rTiEhZiNq1p4LlxVMrJ6z0Cg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-03T03:12:52.060432Z"},"content_sha256":"5c653d703d8a9b933804e438524e71bcbb42aa19316f82ea6eb84cdc89844a31","schema_version":"1.0","event_id":"sha256:5c653d703d8a9b933804e438524e71bcbb42aa19316f82ea6eb84cdc89844a31"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/A6KQI6NISVJRNPZ5LS4E6WJ7KV/bundle.json","state_url":"https://pith.science/pith/A6KQI6NISVJRNPZ5LS4E6WJ7KV/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/A6KQI6NISVJRNPZ5LS4E6WJ7KV/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-03T03:12:52Z","links":{"resolver":"https://pith.science/pith/A6KQI6NISVJRNPZ5LS4E6WJ7KV","bundle":"https://pith.science/pith/A6KQI6NISVJRNPZ5LS4E6WJ7KV/bundle.json","state":"https://pith.science/pith/A6KQI6NISVJRNPZ5LS4E6WJ7KV/state.json","well_known_bundle":"https://pith.science/.well-known/pith/A6KQI6NISVJRNPZ5LS4E6WJ7KV/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:A6KQI6NISVJRNPZ5LS4E6WJ7KV","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"8e75cfe0a27892faa1ef8e19a74f8fcb7398a192e22d321fe71f29ff47bbc049","cross_cats_sorted":["physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-10-31T17:14:47Z","title_canon_sha256":"540440fdc4c148f7dd9f4058a6d60ff8bb42d1b91232591ca238a3398aa20da1"},"schema_version":"1.0","source":{"id":"1610.10021","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1610.10021","created_at":"2026-05-18T01:00:46Z"},{"alias_kind":"arxiv_version","alias_value":"1610.10021v1","created_at":"2026-05-18T01:00:46Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1610.10021","created_at":"2026-05-18T01:00:46Z"},{"alias_kind":"pith_short_12","alias_value":"A6KQI6NISVJR","created_at":"2026-05-18T12:30:04Z"},{"alias_kind":"pith_short_16","alias_value":"A6KQI6NISVJRNPZ5","created_at":"2026-05-18T12:30:04Z"},{"alias_kind":"pith_short_8","alias_value":"A6KQI6NI","created_at":"2026-05-18T12:30:04Z"}],"graph_snapshots":[{"event_id":"sha256:5c653d703d8a9b933804e438524e71bcbb42aa19316f82ea6eb84cdc89844a31","target":"graph","created_at":"2026-05-18T01:00:46Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Fluorescein is perhaps the most commonly used substance to visualize tear film thickness and dynamics; better understanding of this process aids understanding of dry eye syndrome which afflicts millions of people. We study a mathematical model for tear film flow, evaporation, solutal transport and fluorescence over the exposed ocular surface during the interblink. Transport of the fluorescein ion by fluid flow in the tear film affects the intensity of fluorescence via changes in concentration and tear film thickness. Evaporation causes increased osmolarity and potential irritation over the ocu","authors_text":"Longfei Li, P. E. King-Smith, R. J. Braun, W. D. Henshaw","cross_cats":["physics.bio-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-10-31T17:14:47Z","title":"Computed Flow and Fluorescence Over the Ocular Surface"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1610.10021","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:0d7fc7e3c5306fb2147db8f4a16d1da741c23ac706d15e8eb03214923b8ac573","target":"record","created_at":"2026-05-18T01:00:46Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"8e75cfe0a27892faa1ef8e19a74f8fcb7398a192e22d321fe71f29ff47bbc049","cross_cats_sorted":["physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-10-31T17:14:47Z","title_canon_sha256":"540440fdc4c148f7dd9f4058a6d60ff8bb42d1b91232591ca238a3398aa20da1"},"schema_version":"1.0","source":{"id":"1610.10021","kind":"arxiv","version":1}},"canonical_sha256":"07950479a8955316bf3d5cb84f593f55610a7310108b9bec53ac836becdbd538","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"07950479a8955316bf3d5cb84f593f55610a7310108b9bec53ac836becdbd538","first_computed_at":"2026-05-18T01:00:46.721196Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:00:46.721196Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"1shbPm8LQMFax8CFoTTljONxIDcJfEtVMVgsjsto9ydDHRCjA4jLJcapyOJQDfDK0y+xm61u3vt7R3XHFQiwAA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:00:46.721685Z","signed_message":"canonical_sha256_bytes"},"source_id":"1610.10021","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:0d7fc7e3c5306fb2147db8f4a16d1da741c23ac706d15e8eb03214923b8ac573","sha256:5c653d703d8a9b933804e438524e71bcbb42aa19316f82ea6eb84cdc89844a31"],"state_sha256":"a2daba8d93cec021904d67ddcb42cd444246412d58e879e47fa18f8e312d436b"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"rebS1dVgWoQlT8aahG2Tk09BpkFp1vMm4YcqQWkCZ419wtnAP2mNWd++pKoHhIcit/yScCgpWyYRTuR4WZkfAg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-03T03:12:52.062401Z","bundle_sha256":"7fe187a477c481677c67ab1ae027cc4a20e4c232ac5a53de67b538e46cb2c889"}}