{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2012:AMI2L753EXPH6UJ5AMUNSEZZ5B","short_pith_number":"pith:AMI2L753","canonical_record":{"source":{"id":"1202.6326","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2012-02-25T18:14:25Z","cross_cats_sorted":["cond-mat.dis-nn","cond-mat.stat-mech","physics.bio-ph"],"title_canon_sha256":"2d8e680501c02eeaeffe1de81ee1bae7fc9387f329232bc2654d29e7515a1551","abstract_canon_sha256":"6ffb02c22141ce3dab30d3876ab05be773c2da72351affff719cfab151f0216b"},"schema_version":"1.0"},"canonical_sha256":"0311a5ffbb25de7f513d0328d91339e87a0927f543e4911dde0a6c39a8774053","source":{"kind":"arxiv","id":"1202.6326","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1202.6326","created_at":"2026-05-18T01:58:18Z"},{"alias_kind":"arxiv_version","alias_value":"1202.6326v2","created_at":"2026-05-18T01:58:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1202.6326","created_at":"2026-05-18T01:58:18Z"},{"alias_kind":"pith_short_12","alias_value":"AMI2L753EXPH","created_at":"2026-05-18T12:26:58Z"},{"alias_kind":"pith_short_16","alias_value":"AMI2L753EXPH6UJ5","created_at":"2026-05-18T12:26:58Z"},{"alias_kind":"pith_short_8","alias_value":"AMI2L753","created_at":"2026-05-18T12:26:58Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2012:AMI2L753EXPH6UJ5AMUNSEZZ5B","target":"record","payload":{"canonical_record":{"source":{"id":"1202.6326","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2012-02-25T18:14:25Z","cross_cats_sorted":["cond-mat.dis-nn","cond-mat.stat-mech","physics.bio-ph"],"title_canon_sha256":"2d8e680501c02eeaeffe1de81ee1bae7fc9387f329232bc2654d29e7515a1551","abstract_canon_sha256":"6ffb02c22141ce3dab30d3876ab05be773c2da72351affff719cfab151f0216b"},"schema_version":"1.0"},"canonical_sha256":"0311a5ffbb25de7f513d0328d91339e87a0927f543e4911dde0a6c39a8774053","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:58:18.622418Z","signature_b64":"eQElObpnQkvuZgSun1qTbReWwpniSC5bzb5QOEXsbX4t8xbFPdpek7z4Sw5DHH4if1Hlkaazuh4rBNCZ/e4SBw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"0311a5ffbb25de7f513d0328d91339e87a0927f543e4911dde0a6c39a8774053","last_reissued_at":"2026-05-18T01:58:18.621860Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:58:18.621860Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1202.6326","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:58:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"nUwCmX3anKIB2bKoJgCPkikUbI02SH2GDy4HGM7H7nKjzdpbAVWgGERrt8zMBBEvEYTzWY6xHlFisKjbo9I2AA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-28T03:00:25.152363Z"},"content_sha256":"9b1428c96d9e33b96fcda6c3c8a35e256bc0026983a505e8f4144b546581a224","schema_version":"1.0","event_id":"sha256:9b1428c96d9e33b96fcda6c3c8a35e256bc0026983a505e8f4144b546581a224"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2012:AMI2L753EXPH6UJ5AMUNSEZZ5B","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Parallel processing in immune networks","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.dis-nn","cond-mat.stat-mech","physics.bio-ph"],"primary_cat":"q-bio.CB","authors_text":"Adriano Barra, Andrea Galluzzi, Elena Agliari, Francesco Guerra, Francesco Moauro, Silvia Bartolucci","submitted_at":"2012-02-25T18:14:25Z","abstract_excerpt":"In this work we adopt a statistical mechanics approach to investigate basic, systemic features exhibited by adaptive immune systems. The lymphocyte network made by B-cells and T-cells is modeled by a bipartite spin-glass, where, following biological prescriptions, links connecting B-cells and T-cells are sparse. Interestingly, the dilution performed on links is shown to make the system able to orchestrate parallel strategies to fight several pathogens at the same time; this multitasking capability constitutes a remarkable, key property of immune systems as multiple antigens are always present "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1202.6326","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:58:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"9vI4BoReHJFxCZyWjO5OQxdQB0JjLPIbTJ92KSrN6PEtCO5k0KwNzI9p2gOfHHyLfKTId0YYWaiRoz8xwazSBQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-28T03:00:25.152729Z"},"content_sha256":"a78dea35504bd4d18ee4eaedf2233ed1b7b5cad141d9005e1d640d3a49b3404c","schema_version":"1.0","event_id":"sha256:a78dea35504bd4d18ee4eaedf2233ed1b7b5cad141d9005e1d640d3a49b3404c"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/AMI2L753EXPH6UJ5AMUNSEZZ5B/bundle.json","state_url":"https://pith.science/pith/AMI2L753EXPH6UJ5AMUNSEZZ5B/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/AMI2L753EXPH6UJ5AMUNSEZZ5B/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-28T03:00:25Z","links":{"resolver":"https://pith.science/pith/AMI2L753EXPH6UJ5AMUNSEZZ5B","bundle":"https://pith.science/pith/AMI2L753EXPH6UJ5AMUNSEZZ5B/bundle.json","state":"https://pith.science/pith/AMI2L753EXPH6UJ5AMUNSEZZ5B/state.json","well_known_bundle":"https://pith.science/.well-known/pith/AMI2L753EXPH6UJ5AMUNSEZZ5B/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2012:AMI2L753EXPH6UJ5AMUNSEZZ5B","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"6ffb02c22141ce3dab30d3876ab05be773c2da72351affff719cfab151f0216b","cross_cats_sorted":["cond-mat.dis-nn","cond-mat.stat-mech","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2012-02-25T18:14:25Z","title_canon_sha256":"2d8e680501c02eeaeffe1de81ee1bae7fc9387f329232bc2654d29e7515a1551"},"schema_version":"1.0","source":{"id":"1202.6326","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1202.6326","created_at":"2026-05-18T01:58:18Z"},{"alias_kind":"arxiv_version","alias_value":"1202.6326v2","created_at":"2026-05-18T01:58:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1202.6326","created_at":"2026-05-18T01:58:18Z"},{"alias_kind":"pith_short_12","alias_value":"AMI2L753EXPH","created_at":"2026-05-18T12:26:58Z"},{"alias_kind":"pith_short_16","alias_value":"AMI2L753EXPH6UJ5","created_at":"2026-05-18T12:26:58Z"},{"alias_kind":"pith_short_8","alias_value":"AMI2L753","created_at":"2026-05-18T12:26:58Z"}],"graph_snapshots":[{"event_id":"sha256:a78dea35504bd4d18ee4eaedf2233ed1b7b5cad141d9005e1d640d3a49b3404c","target":"graph","created_at":"2026-05-18T01:58:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"In this work we adopt a statistical mechanics approach to investigate basic, systemic features exhibited by adaptive immune systems. The lymphocyte network made by B-cells and T-cells is modeled by a bipartite spin-glass, where, following biological prescriptions, links connecting B-cells and T-cells are sparse. Interestingly, the dilution performed on links is shown to make the system able to orchestrate parallel strategies to fight several pathogens at the same time; this multitasking capability constitutes a remarkable, key property of immune systems as multiple antigens are always present ","authors_text":"Adriano Barra, Andrea Galluzzi, Elena Agliari, Francesco Guerra, Francesco Moauro, Silvia Bartolucci","cross_cats":["cond-mat.dis-nn","cond-mat.stat-mech","physics.bio-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2012-02-25T18:14:25Z","title":"Parallel processing in immune networks"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1202.6326","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:9b1428c96d9e33b96fcda6c3c8a35e256bc0026983a505e8f4144b546581a224","target":"record","created_at":"2026-05-18T01:58:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"6ffb02c22141ce3dab30d3876ab05be773c2da72351affff719cfab151f0216b","cross_cats_sorted":["cond-mat.dis-nn","cond-mat.stat-mech","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2012-02-25T18:14:25Z","title_canon_sha256":"2d8e680501c02eeaeffe1de81ee1bae7fc9387f329232bc2654d29e7515a1551"},"schema_version":"1.0","source":{"id":"1202.6326","kind":"arxiv","version":2}},"canonical_sha256":"0311a5ffbb25de7f513d0328d91339e87a0927f543e4911dde0a6c39a8774053","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"0311a5ffbb25de7f513d0328d91339e87a0927f543e4911dde0a6c39a8774053","first_computed_at":"2026-05-18T01:58:18.621860Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:58:18.621860Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"eQElObpnQkvuZgSun1qTbReWwpniSC5bzb5QOEXsbX4t8xbFPdpek7z4Sw5DHH4if1Hlkaazuh4rBNCZ/e4SBw==","signature_status":"signed_v1","signed_at":"2026-05-18T01:58:18.622418Z","signed_message":"canonical_sha256_bytes"},"source_id":"1202.6326","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:9b1428c96d9e33b96fcda6c3c8a35e256bc0026983a505e8f4144b546581a224","sha256:a78dea35504bd4d18ee4eaedf2233ed1b7b5cad141d9005e1d640d3a49b3404c"],"state_sha256":"ed101c8e146a5f7dd8b17f280295deec045c48574e1f73c246d867bd6fe7dadd"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"b50eBhLg7KZaAj/Uzp4xV6F9eeN6xFpiAU0GtodMis5tRnR5d75qpihn5CqHP/aeoAjrJp0+jfCidEAkAn70AQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-28T03:00:25.154909Z","bundle_sha256":"000246e7a561eed9bdc46180e92c697195937d8ccdb71485dbdeb43da8bc0991"}}