{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2020:AMJVBLXHVAYMHXET2K5GTI7A4M","short_pith_number":"pith:AMJVBLXH","canonical_record":{"source":{"id":"2001.05127","kind":"arxiv","version":5},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2020-01-15T04:22:15Z","cross_cats_sorted":[],"title_canon_sha256":"03fbe16677a02d2eb1e1c33936b14a1f379ab850e69a086c769c98bcedf4f82b","abstract_canon_sha256":"9b4d430ee63f32f510678af36ebae39647f78844a9476f9bddb7d60d8a28c150"},"schema_version":"1.0"},"canonical_sha256":"031350aee7a830c3dc93d2ba69a3e0e314b77b79f6ba9deb7e525f72486adea9","source":{"kind":"arxiv","id":"2001.05127","version":5},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2001.05127","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"arxiv_version","alias_value":"2001.05127v5","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2001.05127","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"pith_short_12","alias_value":"AMJVBLXHVAYM","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"pith_short_16","alias_value":"AMJVBLXHVAYMHXET","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"pith_short_8","alias_value":"AMJVBLXH","created_at":"2026-07-05T01:22:15Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2020:AMJVBLXHVAYMHXET2K5GTI7A4M","target":"record","payload":{"canonical_record":{"source":{"id":"2001.05127","kind":"arxiv","version":5},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2020-01-15T04:22:15Z","cross_cats_sorted":[],"title_canon_sha256":"03fbe16677a02d2eb1e1c33936b14a1f379ab850e69a086c769c98bcedf4f82b","abstract_canon_sha256":"9b4d430ee63f32f510678af36ebae39647f78844a9476f9bddb7d60d8a28c150"},"schema_version":"1.0"},"canonical_sha256":"031350aee7a830c3dc93d2ba69a3e0e314b77b79f6ba9deb7e525f72486adea9","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T01:22:15.530850Z","signature_b64":"qTccumRENDBE4rDBJ4HVUNOsAYAIgXHTKM0SseL4v/Ufw7U8gCquJYCpg1AY5N98ZsFZ/PFttp+Lc5F6L613BQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"031350aee7a830c3dc93d2ba69a3e0e314b77b79f6ba9deb7e525f72486adea9","last_reissued_at":"2026-07-05T01:22:15.530349Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T01:22:15.530349Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2001.05127","source_version":5,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T01:22:15Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"iNPxcdFxNC6NifABzAegxeuksQRUOalzrpGb7+pg42991Z2uXmG1dZvVGFFnsniejnLGYGlXIfCsbM4nQ9cHDg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-01T12:31:11.708768Z"},"content_sha256":"455b165825d914e34f7c4b0aa44c54b3244f4ab52eda5aa007c31baf53b6f11b","schema_version":"1.0","event_id":"sha256:455b165825d914e34f7c4b0aa44c54b3244f4ab52eda5aa007c31baf53b6f11b"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2020:AMJVBLXHVAYMHXET2K5GTI7A4M","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Recommendations to enhance rigor and reproducibility in biomedical research","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.OT","authors_text":"Casey S. Greene, Jaqueline J. Brito, Jason H. Moore, Jun Li, Lana X. Garmire, Nicole A. Nogoy, Serghei Mangul","submitted_at":"2020-01-15T04:22:15Z","abstract_excerpt":"Computational methods have reshaped the landscape of modern biology. While the biomedical community is increasingly dependent on computational tools, the mechanisms ensuring open data, open software, and reproducibility are variably enforced by academic institutions, funders, and publishers. Publications may present academic software for which essential materials are or become unavailable, such as source code and documentation. Publications that lack such information compromise the role of peer review in evaluating technical strength and scientific contribution. Incomplete ancillary informatio"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2001.05127","kind":"arxiv","version":5},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2001.05127/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T01:22:15Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"JsMlpKaAq/Zvb/dgnWhThbJhTxnSOBS0RY4KbVIl3Oar1cXY3zUvEwZfopOfBq7Gpvpc0HXhuAjla1QvtC9ECg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-01T12:31:11.709261Z"},"content_sha256":"39d992b4ba851df4240471a03b414e2f299522d0e02711b809283dda8ef655cf","schema_version":"1.0","event_id":"sha256:39d992b4ba851df4240471a03b414e2f299522d0e02711b809283dda8ef655cf"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/AMJVBLXHVAYMHXET2K5GTI7A4M/bundle.json","state_url":"https://pith.science/pith/AMJVBLXHVAYMHXET2K5GTI7A4M/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/AMJVBLXHVAYMHXET2K5GTI7A4M/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-01T12:31:11Z","links":{"resolver":"https://pith.science/pith/AMJVBLXHVAYMHXET2K5GTI7A4M","bundle":"https://pith.science/pith/AMJVBLXHVAYMHXET2K5GTI7A4M/bundle.json","state":"https://pith.science/pith/AMJVBLXHVAYMHXET2K5GTI7A4M/state.json","well_known_bundle":"https://pith.science/.well-known/pith/AMJVBLXHVAYMHXET2K5GTI7A4M/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2020:AMJVBLXHVAYMHXET2K5GTI7A4M","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"9b4d430ee63f32f510678af36ebae39647f78844a9476f9bddb7d60d8a28c150","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2020-01-15T04:22:15Z","title_canon_sha256":"03fbe16677a02d2eb1e1c33936b14a1f379ab850e69a086c769c98bcedf4f82b"},"schema_version":"1.0","source":{"id":"2001.05127","kind":"arxiv","version":5}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2001.05127","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"arxiv_version","alias_value":"2001.05127v5","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2001.05127","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"pith_short_12","alias_value":"AMJVBLXHVAYM","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"pith_short_16","alias_value":"AMJVBLXHVAYMHXET","created_at":"2026-07-05T01:22:15Z"},{"alias_kind":"pith_short_8","alias_value":"AMJVBLXH","created_at":"2026-07-05T01:22:15Z"}],"graph_snapshots":[{"event_id":"sha256:39d992b4ba851df4240471a03b414e2f299522d0e02711b809283dda8ef655cf","target":"graph","created_at":"2026-07-05T01:22:15Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2001.05127/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Computational methods have reshaped the landscape of modern biology. While the biomedical community is increasingly dependent on computational tools, the mechanisms ensuring open data, open software, and reproducibility are variably enforced by academic institutions, funders, and publishers. Publications may present academic software for which essential materials are or become unavailable, such as source code and documentation. Publications that lack such information compromise the role of peer review in evaluating technical strength and scientific contribution. Incomplete ancillary informatio","authors_text":"Casey S. Greene, Jaqueline J. Brito, Jason H. Moore, Jun Li, Lana X. Garmire, Nicole A. Nogoy, Serghei Mangul","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2020-01-15T04:22:15Z","title":"Recommendations to enhance rigor and reproducibility in biomedical research"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2001.05127","kind":"arxiv","version":5},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:455b165825d914e34f7c4b0aa44c54b3244f4ab52eda5aa007c31baf53b6f11b","target":"record","created_at":"2026-07-05T01:22:15Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"9b4d430ee63f32f510678af36ebae39647f78844a9476f9bddb7d60d8a28c150","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.OT","submitted_at":"2020-01-15T04:22:15Z","title_canon_sha256":"03fbe16677a02d2eb1e1c33936b14a1f379ab850e69a086c769c98bcedf4f82b"},"schema_version":"1.0","source":{"id":"2001.05127","kind":"arxiv","version":5}},"canonical_sha256":"031350aee7a830c3dc93d2ba69a3e0e314b77b79f6ba9deb7e525f72486adea9","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"031350aee7a830c3dc93d2ba69a3e0e314b77b79f6ba9deb7e525f72486adea9","first_computed_at":"2026-07-05T01:22:15.530349Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T01:22:15.530349Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"qTccumRENDBE4rDBJ4HVUNOsAYAIgXHTKM0SseL4v/Ufw7U8gCquJYCpg1AY5N98ZsFZ/PFttp+Lc5F6L613BQ==","signature_status":"signed_v1","signed_at":"2026-07-05T01:22:15.530850Z","signed_message":"canonical_sha256_bytes"},"source_id":"2001.05127","source_kind":"arxiv","source_version":5}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:455b165825d914e34f7c4b0aa44c54b3244f4ab52eda5aa007c31baf53b6f11b","sha256:39d992b4ba851df4240471a03b414e2f299522d0e02711b809283dda8ef655cf"],"state_sha256":"b270a7ba3bf5c265454549c974062b471b21a776569d5c0df158f4a7e34a7a07"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"jyjLoi4TFfPnH4SUbl4vOzPAcPlBBL5I2a86LkRnDDy7YqOf6D/F9ehjEQC4gMXQy++H6dks8wDZvEUIh184AA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-01T12:31:11.713039Z","bundle_sha256":"2c0bcb4b9c14469dc29b62d0fc3c9e896d9b5185ee1ba6791996a3407bd1fdae"}}