{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2013:AYMYLQBNQYSAX2A4KISZ5SLS5B","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"c6e5245dc140c15d37526e436d3336609dccca6cd921ea8515edf635c9cdcffe","cross_cats_sorted":["q-bio.GN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2013-08-22T18:38:52Z","title_canon_sha256":"020158cb73f00a390881007827b053404a15a68be79467822de141735ddebc1a"},"schema_version":"1.0","source":{"id":"1308.4951","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1308.4951","created_at":"2026-05-18T03:15:19Z"},{"alias_kind":"arxiv_version","alias_value":"1308.4951v1","created_at":"2026-05-18T03:15:19Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1308.4951","created_at":"2026-05-18T03:15:19Z"},{"alias_kind":"pith_short_12","alias_value":"AYMYLQBNQYSA","created_at":"2026-05-18T12:27:38Z"},{"alias_kind":"pith_short_16","alias_value":"AYMYLQBNQYSAX2A4","created_at":"2026-05-18T12:27:38Z"},{"alias_kind":"pith_short_8","alias_value":"AYMYLQBN","created_at":"2026-05-18T12:27:38Z"}],"graph_snapshots":[{"event_id":"sha256:112de16827367299b4b59161ba221744d6c161a80dbfc2bed7afdab1ef87237a","target":"graph","created_at":"2026-05-18T03:15:19Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The role of positive selection in human evolution remains controversial. On the one hand, scans for positive selection have identified hundreds of candidate loci and the genome-wide patterns of polymorphism show signatures consistent with frequent positive selection. On the other hand, recent studies have argued that many of the candidate loci are false positives and that most apparent genome-wide signatures of adaptation are in fact due to reduction of neutral diversity by linked recurrent deleterious mutations, known as background selection. Here we analyze human polymorphism data from the 1","authors_text":"David Enard, Dmitri Petrov, Philipp W. Messer","cross_cats":["q-bio.GN"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2013-08-22T18:38:52Z","title":"Genome wide signals of pervasive positive selection in human evolution"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1308.4951","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:137d6963ffb74da68882bf267b6b3e4fdd851e79ab6201110a2dd3c38129f360","target":"record","created_at":"2026-05-18T03:15:19Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"c6e5245dc140c15d37526e436d3336609dccca6cd921ea8515edf635c9cdcffe","cross_cats_sorted":["q-bio.GN"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.PE","submitted_at":"2013-08-22T18:38:52Z","title_canon_sha256":"020158cb73f00a390881007827b053404a15a68be79467822de141735ddebc1a"},"schema_version":"1.0","source":{"id":"1308.4951","kind":"arxiv","version":1}},"canonical_sha256":"061985c02d86240be81c52259ec972e87cba3871f47c7232986f50196c29d1fe","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"061985c02d86240be81c52259ec972e87cba3871f47c7232986f50196c29d1fe","first_computed_at":"2026-05-18T03:15:19.237405Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T03:15:19.237405Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"UtNCet0fU43Qb1GsYcLlVLCJz32r+AeuRzrZ+s7CQgNeebO329BMrmI4d9taa845bnByu8oc5eD1tnTdL2qqDg==","signature_status":"signed_v1","signed_at":"2026-05-18T03:15:19.238156Z","signed_message":"canonical_sha256_bytes"},"source_id":"1308.4951","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:137d6963ffb74da68882bf267b6b3e4fdd851e79ab6201110a2dd3c38129f360","sha256:112de16827367299b4b59161ba221744d6c161a80dbfc2bed7afdab1ef87237a"],"state_sha256":"c838d2b4de9407e5b47e7883b4f4fe36fce0a91cbd2529a8324e89d8691d1cc2"}