{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:BTVDCWUG5W6CLS6T4SJ4RFI4WA","short_pith_number":"pith:BTVDCWUG","canonical_record":{"source":{"id":"1906.06061","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-06-14T07:50:19Z","cross_cats_sorted":[],"title_canon_sha256":"2a017f8b85ea9293fbe7b801a8ae00f4ed097e73c9c5234a9a219b48b1ec388a","abstract_canon_sha256":"03ee18b780c9f98198c7b4ed9156440be4ec93b3d7dc2a169e616496f629a21d"},"schema_version":"1.0"},"canonical_sha256":"0cea315a86edbc25cbd3e493c8951cb036d63450ecbf8de6f6037d71cffa9295","source":{"kind":"arxiv","id":"1906.06061","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1906.06061","created_at":"2026-05-17T23:43:19Z"},{"alias_kind":"arxiv_version","alias_value":"1906.06061v1","created_at":"2026-05-17T23:43:19Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1906.06061","created_at":"2026-05-17T23:43:19Z"},{"alias_kind":"pith_short_12","alias_value":"BTVDCWUG5W6C","created_at":"2026-05-18T12:33:12Z"},{"alias_kind":"pith_short_16","alias_value":"BTVDCWUG5W6CLS6T","created_at":"2026-05-18T12:33:12Z"},{"alias_kind":"pith_short_8","alias_value":"BTVDCWUG","created_at":"2026-05-18T12:33:12Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:BTVDCWUG5W6CLS6T4SJ4RFI4WA","target":"record","payload":{"canonical_record":{"source":{"id":"1906.06061","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-06-14T07:50:19Z","cross_cats_sorted":[],"title_canon_sha256":"2a017f8b85ea9293fbe7b801a8ae00f4ed097e73c9c5234a9a219b48b1ec388a","abstract_canon_sha256":"03ee18b780c9f98198c7b4ed9156440be4ec93b3d7dc2a169e616496f629a21d"},"schema_version":"1.0"},"canonical_sha256":"0cea315a86edbc25cbd3e493c8951cb036d63450ecbf8de6f6037d71cffa9295","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:43:19.872359Z","signature_b64":"Xwo4yCKWU30fQMcFpnSyd+l9jNq+or+RZb5cUj8O2MCoMrIMNFNP9caslc6PmX/DyEQxvSvRHwJqUtiXfRs4Bg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"0cea315a86edbc25cbd3e493c8951cb036d63450ecbf8de6f6037d71cffa9295","last_reissued_at":"2026-05-17T23:43:19.871810Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:43:19.871810Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1906.06061","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:43:19Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Jbk9GIa6jKPhBpwLYQIkeCFG2dlAWJcE0gS4ikmmkxz+tgquAG60xBRY9NeG+J2Mnjm/fjftrKSb79EkhWYDBQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-07T14:44:33.550090Z"},"content_sha256":"5b79a6fab6ee3037c14e81b36d292b27693ff21b8c7c4c3c884fd916cc324b0b","schema_version":"1.0","event_id":"sha256:5b79a6fab6ee3037c14e81b36d292b27693ff21b8c7c4c3c884fd916cc324b0b"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:BTVDCWUG5W6CLS6T4SJ4RFI4WA","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Perfusion and apparent oxygenation in the human placenta (PERFOX)","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.med-ph","authors_text":"Alison Ho, Anita A. Harteveld, Clemens Bos, Enrico De Vita, Jana Hutter, Jonathan OMuircheartaigh, Joseph V Hajnal, Laurence H. Jackson, Lucy Chappell, Mary Rutherford, Matthias J. P. van Osch, Suzanne Franklin","submitted_at":"2019-06-14T07:50:19Z","abstract_excerpt":"Purpose: To study placental function - both perfusion and an oxygenation surrogate (T2*)-simultaneously and quantitatively in-vivo.\n  Methods: 15 pregnant women were scanned on a 3T MR scanner. For perfusion measurements, a velocity selective arterial spin labelling preparation module was placed before a multi-echo gradient echo EPI readout to integrate T2* and perfusion measurements in one joint perfusion-oxygenation (PERFOX) acquisition. Joint motion correction and quantification were performed to evaluate changes in T2* and perfusion over GA.\n  Results: The optimised integrated PERFOX proto"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1906.06061","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:43:19Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"8CoHwJt79F5tEcnVisrb/mhNBXo0oL1oCNqUcHlUGuMoUqLa2Km+P8mwXTEKdSSCtarFuM028+fy4gZzPt3ODQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-07T14:44:33.550457Z"},"content_sha256":"d0199e9c5474ad53bab41be66d7390c17381ed533b7711d8cea7d690b3079fa6","schema_version":"1.0","event_id":"sha256:d0199e9c5474ad53bab41be66d7390c17381ed533b7711d8cea7d690b3079fa6"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/BTVDCWUG5W6CLS6T4SJ4RFI4WA/bundle.json","state_url":"https://pith.science/pith/BTVDCWUG5W6CLS6T4SJ4RFI4WA/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/BTVDCWUG5W6CLS6T4SJ4RFI4WA/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-07T14:44:33Z","links":{"resolver":"https://pith.science/pith/BTVDCWUG5W6CLS6T4SJ4RFI4WA","bundle":"https://pith.science/pith/BTVDCWUG5W6CLS6T4SJ4RFI4WA/bundle.json","state":"https://pith.science/pith/BTVDCWUG5W6CLS6T4SJ4RFI4WA/state.json","well_known_bundle":"https://pith.science/.well-known/pith/BTVDCWUG5W6CLS6T4SJ4RFI4WA/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:BTVDCWUG5W6CLS6T4SJ4RFI4WA","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"03ee18b780c9f98198c7b4ed9156440be4ec93b3d7dc2a169e616496f629a21d","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-06-14T07:50:19Z","title_canon_sha256":"2a017f8b85ea9293fbe7b801a8ae00f4ed097e73c9c5234a9a219b48b1ec388a"},"schema_version":"1.0","source":{"id":"1906.06061","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1906.06061","created_at":"2026-05-17T23:43:19Z"},{"alias_kind":"arxiv_version","alias_value":"1906.06061v1","created_at":"2026-05-17T23:43:19Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1906.06061","created_at":"2026-05-17T23:43:19Z"},{"alias_kind":"pith_short_12","alias_value":"BTVDCWUG5W6C","created_at":"2026-05-18T12:33:12Z"},{"alias_kind":"pith_short_16","alias_value":"BTVDCWUG5W6CLS6T","created_at":"2026-05-18T12:33:12Z"},{"alias_kind":"pith_short_8","alias_value":"BTVDCWUG","created_at":"2026-05-18T12:33:12Z"}],"graph_snapshots":[{"event_id":"sha256:d0199e9c5474ad53bab41be66d7390c17381ed533b7711d8cea7d690b3079fa6","target":"graph","created_at":"2026-05-17T23:43:19Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Purpose: To study placental function - both perfusion and an oxygenation surrogate (T2*)-simultaneously and quantitatively in-vivo.\n  Methods: 15 pregnant women were scanned on a 3T MR scanner. For perfusion measurements, a velocity selective arterial spin labelling preparation module was placed before a multi-echo gradient echo EPI readout to integrate T2* and perfusion measurements in one joint perfusion-oxygenation (PERFOX) acquisition. Joint motion correction and quantification were performed to evaluate changes in T2* and perfusion over GA.\n  Results: The optimised integrated PERFOX proto","authors_text":"Alison Ho, Anita A. Harteveld, Clemens Bos, Enrico De Vita, Jana Hutter, Jonathan OMuircheartaigh, Joseph V Hajnal, Laurence H. Jackson, Lucy Chappell, Mary Rutherford, Matthias J. P. van Osch, Suzanne Franklin","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-06-14T07:50:19Z","title":"Perfusion and apparent oxygenation in the human placenta (PERFOX)"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1906.06061","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:5b79a6fab6ee3037c14e81b36d292b27693ff21b8c7c4c3c884fd916cc324b0b","target":"record","created_at":"2026-05-17T23:43:19Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"03ee18b780c9f98198c7b4ed9156440be4ec93b3d7dc2a169e616496f629a21d","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-06-14T07:50:19Z","title_canon_sha256":"2a017f8b85ea9293fbe7b801a8ae00f4ed097e73c9c5234a9a219b48b1ec388a"},"schema_version":"1.0","source":{"id":"1906.06061","kind":"arxiv","version":1}},"canonical_sha256":"0cea315a86edbc25cbd3e493c8951cb036d63450ecbf8de6f6037d71cffa9295","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"0cea315a86edbc25cbd3e493c8951cb036d63450ecbf8de6f6037d71cffa9295","first_computed_at":"2026-05-17T23:43:19.871810Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:43:19.871810Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"Xwo4yCKWU30fQMcFpnSyd+l9jNq+or+RZb5cUj8O2MCoMrIMNFNP9caslc6PmX/DyEQxvSvRHwJqUtiXfRs4Bg==","signature_status":"signed_v1","signed_at":"2026-05-17T23:43:19.872359Z","signed_message":"canonical_sha256_bytes"},"source_id":"1906.06061","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:5b79a6fab6ee3037c14e81b36d292b27693ff21b8c7c4c3c884fd916cc324b0b","sha256:d0199e9c5474ad53bab41be66d7390c17381ed533b7711d8cea7d690b3079fa6"],"state_sha256":"e146266c8322de5b581f91fbdf4807806854b6d136cd4b67d40acf5526d89b45"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"opvC3KJUXgvQfOpG8vUxBPsj8qUYrPYlZOWreXNZ4D+OqKAJkHorvOVWIxLSfZgPF/A2vzkJWDQAKToM2qhGBA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-07T14:44:33.552308Z","bundle_sha256":"0808252a2d3f4c63fac867be0a4f8aff0f615f124f5e250e28dffa6e729ef7b1"}}