{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2022:BZJ4Q57IVDRQPL67YHRXFYHNWX","short_pith_number":"pith:BZJ4Q57I","canonical_record":{"source":{"id":"2204.09278","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-04-20T07:40:01Z","cross_cats_sorted":[],"title_canon_sha256":"646337c2736601f4d2935944e388e566d86b2a3f8010910a48bc2c2060eb2c0e","abstract_canon_sha256":"ee05fcb1c7fad6b077c07ba5d36b90c6b97eb35ce73ec59023090f09aaf2c869"},"schema_version":"1.0"},"canonical_sha256":"0e53c877e8a8e307afdfc1e372e0edb5dbe9c84960b6cda437fa7e775da82436","source":{"kind":"arxiv","id":"2204.09278","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2204.09278","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"arxiv_version","alias_value":"2204.09278v1","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2204.09278","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"pith_short_12","alias_value":"BZJ4Q57IVDRQ","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"pith_short_16","alias_value":"BZJ4Q57IVDRQPL67","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"pith_short_8","alias_value":"BZJ4Q57I","created_at":"2026-07-05T04:16:22Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2022:BZJ4Q57IVDRQPL67YHRXFYHNWX","target":"record","payload":{"canonical_record":{"source":{"id":"2204.09278","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-04-20T07:40:01Z","cross_cats_sorted":[],"title_canon_sha256":"646337c2736601f4d2935944e388e566d86b2a3f8010910a48bc2c2060eb2c0e","abstract_canon_sha256":"ee05fcb1c7fad6b077c07ba5d36b90c6b97eb35ce73ec59023090f09aaf2c869"},"schema_version":"1.0"},"canonical_sha256":"0e53c877e8a8e307afdfc1e372e0edb5dbe9c84960b6cda437fa7e775da82436","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T04:16:22.865052Z","signature_b64":"9rUyktj0Xb81cUuRW7OGH20QrB8Y6GUk7kynxu2G0PaYC6zH+iI4b7IkgvaFg3CSdo1NiaJAyhKrhb2rM2fUCw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"0e53c877e8a8e307afdfc1e372e0edb5dbe9c84960b6cda437fa7e775da82436","last_reissued_at":"2026-07-05T04:16:22.864630Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T04:16:22.864630Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2204.09278","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:16:22Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"maDahPzL9GJoVegq/Q0boP/510I3TMYYZt5KxaLVPhYn/6zc2/I1lPfKPezr8y1W3a8BrkARW4YoIO/kQ4VtDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-03T21:47:50.884824Z"},"content_sha256":"c992f8d862a3e6f93709d415dcfc1a4e68ba9978bfae886bc693302a08bb3e34","schema_version":"1.0","event_id":"sha256:c992f8d862a3e6f93709d415dcfc1a4e68ba9978bfae886bc693302a08bb3e34"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2022:BZJ4Q57IVDRQPL67YHRXFYHNWX","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Bone marrow sparing for cervical cancer radiotherapy on multimodality medical images","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"eess.IV","authors_text":"Han Gao, Hanzi Xu, Jie Yuan, Kexin Gan, Xiuming Zhang, Ying Sun, Yuening Wang","submitted_at":"2022-04-20T07:40:01Z","abstract_excerpt":"Cervical cancer threatens the health of women seriously. Radiotherapy is one of the main therapy methods but with high risk of acute hematologic toxicity. Delineating the bone marrow (BM) for sparing using computer tomography (CT) images to plan before radiotherapy can effectively avoid this risk. Comparing with magnetic resonance (MR) images, CT lacks the ability to express the activity of BM. Thus, in current clinical practice, medical practitioners manually delineate the BM on CT images by corresponding to MR images. However, the time?consuming delineating BM by hand cannot guarantee the ac"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2204.09278","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2204.09278/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:16:22Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"QPSjgO5EcKUlCrxdOfcuyxHoMUqCt4Z/lSnnYjS6jyGVn3mtHfPMNvsV7JaS9Ke2JRtFoZyjaljdTU8pMbT0Dw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-03T21:47:50.885221Z"},"content_sha256":"28cb4c3fa134bba41eeb53570bfd34730c08d77a2c940f3dc0cf07c35eab009b","schema_version":"1.0","event_id":"sha256:28cb4c3fa134bba41eeb53570bfd34730c08d77a2c940f3dc0cf07c35eab009b"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/BZJ4Q57IVDRQPL67YHRXFYHNWX/bundle.json","state_url":"https://pith.science/pith/BZJ4Q57IVDRQPL67YHRXFYHNWX/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/BZJ4Q57IVDRQPL67YHRXFYHNWX/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-03T21:47:50Z","links":{"resolver":"https://pith.science/pith/BZJ4Q57IVDRQPL67YHRXFYHNWX","bundle":"https://pith.science/pith/BZJ4Q57IVDRQPL67YHRXFYHNWX/bundle.json","state":"https://pith.science/pith/BZJ4Q57IVDRQPL67YHRXFYHNWX/state.json","well_known_bundle":"https://pith.science/.well-known/pith/BZJ4Q57IVDRQPL67YHRXFYHNWX/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2022:BZJ4Q57IVDRQPL67YHRXFYHNWX","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"ee05fcb1c7fad6b077c07ba5d36b90c6b97eb35ce73ec59023090f09aaf2c869","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-04-20T07:40:01Z","title_canon_sha256":"646337c2736601f4d2935944e388e566d86b2a3f8010910a48bc2c2060eb2c0e"},"schema_version":"1.0","source":{"id":"2204.09278","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2204.09278","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"arxiv_version","alias_value":"2204.09278v1","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2204.09278","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"pith_short_12","alias_value":"BZJ4Q57IVDRQ","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"pith_short_16","alias_value":"BZJ4Q57IVDRQPL67","created_at":"2026-07-05T04:16:22Z"},{"alias_kind":"pith_short_8","alias_value":"BZJ4Q57I","created_at":"2026-07-05T04:16:22Z"}],"graph_snapshots":[{"event_id":"sha256:28cb4c3fa134bba41eeb53570bfd34730c08d77a2c940f3dc0cf07c35eab009b","target":"graph","created_at":"2026-07-05T04:16:22Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2204.09278/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Cervical cancer threatens the health of women seriously. Radiotherapy is one of the main therapy methods but with high risk of acute hematologic toxicity. Delineating the bone marrow (BM) for sparing using computer tomography (CT) images to plan before radiotherapy can effectively avoid this risk. Comparing with magnetic resonance (MR) images, CT lacks the ability to express the activity of BM. Thus, in current clinical practice, medical practitioners manually delineate the BM on CT images by corresponding to MR images. However, the time?consuming delineating BM by hand cannot guarantee the ac","authors_text":"Han Gao, Hanzi Xu, Jie Yuan, Kexin Gan, Xiuming Zhang, Ying Sun, Yuening Wang","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-04-20T07:40:01Z","title":"Bone marrow sparing for cervical cancer radiotherapy on multimodality medical images"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2204.09278","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:c992f8d862a3e6f93709d415dcfc1a4e68ba9978bfae886bc693302a08bb3e34","target":"record","created_at":"2026-07-05T04:16:22Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"ee05fcb1c7fad6b077c07ba5d36b90c6b97eb35ce73ec59023090f09aaf2c869","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-04-20T07:40:01Z","title_canon_sha256":"646337c2736601f4d2935944e388e566d86b2a3f8010910a48bc2c2060eb2c0e"},"schema_version":"1.0","source":{"id":"2204.09278","kind":"arxiv","version":1}},"canonical_sha256":"0e53c877e8a8e307afdfc1e372e0edb5dbe9c84960b6cda437fa7e775da82436","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"0e53c877e8a8e307afdfc1e372e0edb5dbe9c84960b6cda437fa7e775da82436","first_computed_at":"2026-07-05T04:16:22.864630Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T04:16:22.864630Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"9rUyktj0Xb81cUuRW7OGH20QrB8Y6GUk7kynxu2G0PaYC6zH+iI4b7IkgvaFg3CSdo1NiaJAyhKrhb2rM2fUCw==","signature_status":"signed_v1","signed_at":"2026-07-05T04:16:22.865052Z","signed_message":"canonical_sha256_bytes"},"source_id":"2204.09278","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:c992f8d862a3e6f93709d415dcfc1a4e68ba9978bfae886bc693302a08bb3e34","sha256:28cb4c3fa134bba41eeb53570bfd34730c08d77a2c940f3dc0cf07c35eab009b"],"state_sha256":"0d50ed02bbbe8008894e595c2a3b2e05be284932866894b628059782a49ac6d9"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"0TeQ40/2xZxx2qW5IVtBF55RP6pg+LNunmQa72CxSxCjdgWGWuhbWI4xKZ0gJkVpBGq1IjDG/78GTtTzlL30CA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-03T21:47:50.887929Z","bundle_sha256":"40939d4b8f59efe86587061714802446e2b7d3adb1e67332f533937391ae70b7"}}