{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2021:C66EL4E3GX7UT4GETDR74RVGR5","short_pith_number":"pith:C66EL4E3","canonical_record":{"source":{"id":"2103.04796","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-03-08T14:46:41Z","cross_cats_sorted":["eess.IV"],"title_canon_sha256":"975301f5a5b8b3b8b1451c67351566492eed14caea6b6a7ec9ab16c1c727e8b8","abstract_canon_sha256":"f54a55f0d451fbb9344e36529948c15cb2814faea96d29bc728af3e91c897c17"},"schema_version":"1.0"},"canonical_sha256":"17bc45f09b35ff49f0c498e3fe46a68f5f8804ca64bbfdbc9165c178ff08c31f","source":{"kind":"arxiv","id":"2103.04796","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2103.04796","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"arxiv_version","alias_value":"2103.04796v1","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2103.04796","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"pith_short_12","alias_value":"C66EL4E3GX7U","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"pith_short_16","alias_value":"C66EL4E3GX7UT4GE","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"pith_short_8","alias_value":"C66EL4E3","created_at":"2026-07-05T03:40:18Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2021:C66EL4E3GX7UT4GETDR74RVGR5","target":"record","payload":{"canonical_record":{"source":{"id":"2103.04796","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-03-08T14:46:41Z","cross_cats_sorted":["eess.IV"],"title_canon_sha256":"975301f5a5b8b3b8b1451c67351566492eed14caea6b6a7ec9ab16c1c727e8b8","abstract_canon_sha256":"f54a55f0d451fbb9344e36529948c15cb2814faea96d29bc728af3e91c897c17"},"schema_version":"1.0"},"canonical_sha256":"17bc45f09b35ff49f0c498e3fe46a68f5f8804ca64bbfdbc9165c178ff08c31f","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T03:40:18.567234Z","signature_b64":"X8vfbr4uTnk9JJWJ5EZo7G2VhOXMP4QsBVSsfisZ2ZvWmRJODRbKbPCOpNnMf/ytnwvdajTo5eOfbajWUmGvBQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"17bc45f09b35ff49f0c498e3fe46a68f5f8804ca64bbfdbc9165c178ff08c31f","last_reissued_at":"2026-07-05T03:40:18.566827Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T03:40:18.566827Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2103.04796","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T03:40:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"L2yDhn+NCj8um7radSLc7zkYl190D/iQR1IIxXj7mQr2Va1scxlA7UWV0jdFDJvqM7yKYf7qupUsyJ03TbO5CA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-13T06:34:05.431700Z"},"content_sha256":"c44ce25820a903fc845b64c548b2d5cb8300bbaf02461398e73b4354d8fdd0b1","schema_version":"1.0","event_id":"sha256:c44ce25820a903fc845b64c548b2d5cb8300bbaf02461398e73b4354d8fdd0b1"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2021:C66EL4E3GX7UT4GETDR74RVGR5","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Enhanced hyperspectral tomography for bioimaging by spatiospectral reconstruction","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["eess.IV"],"primary_cat":"physics.med-ph","authors_text":"Edoardo Pasca, Evangelos Papoutsellis, Evelina Ametova, Gemma Fardell, Jakob S. J{\\o}rgensen, Philip J. Withers, Robert J. Cernik, Ryan Warr, Stephan Handschuh","submitted_at":"2021-03-08T14:46:41Z","abstract_excerpt":"Here we apply hyperspectral bright field imaging to collect computed tomographic images with excellent energy resolution (800 eV), applying it for the first time to map the distribution of stain in a fixed biological sample through its characteristic K-edge. Conventionally, because the photons detected at each pixel are distributed across as many as 200 energy channels, energy-selective images are characterised by low count-rates and poor signal-to-noise ratio. This means high X-ray exposures, long scan times and high doses are required to image unique spectral markers. Here, we achieve high q"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2103.04796","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2103.04796/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T03:40:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"bUTMjlKJ/ZeSF0L2LR0BL+o2ol6WquMrZTZNDpRGQEFDRHm8yjR5Zg2LcWcUHeIrIVg0ZKPCaVO4V/7GXe2wCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-13T06:34:05.432079Z"},"content_sha256":"cd16b67426fae0bb080da6c175284bc5c2e1db31b9968007ebaf72182a4d8ac9","schema_version":"1.0","event_id":"sha256:cd16b67426fae0bb080da6c175284bc5c2e1db31b9968007ebaf72182a4d8ac9"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/C66EL4E3GX7UT4GETDR74RVGR5/bundle.json","state_url":"https://pith.science/pith/C66EL4E3GX7UT4GETDR74RVGR5/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/C66EL4E3GX7UT4GETDR74RVGR5/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-13T06:34:05Z","links":{"resolver":"https://pith.science/pith/C66EL4E3GX7UT4GETDR74RVGR5","bundle":"https://pith.science/pith/C66EL4E3GX7UT4GETDR74RVGR5/bundle.json","state":"https://pith.science/pith/C66EL4E3GX7UT4GETDR74RVGR5/state.json","well_known_bundle":"https://pith.science/.well-known/pith/C66EL4E3GX7UT4GETDR74RVGR5/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2021:C66EL4E3GX7UT4GETDR74RVGR5","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"f54a55f0d451fbb9344e36529948c15cb2814faea96d29bc728af3e91c897c17","cross_cats_sorted":["eess.IV"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-03-08T14:46:41Z","title_canon_sha256":"975301f5a5b8b3b8b1451c67351566492eed14caea6b6a7ec9ab16c1c727e8b8"},"schema_version":"1.0","source":{"id":"2103.04796","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2103.04796","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"arxiv_version","alias_value":"2103.04796v1","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2103.04796","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"pith_short_12","alias_value":"C66EL4E3GX7U","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"pith_short_16","alias_value":"C66EL4E3GX7UT4GE","created_at":"2026-07-05T03:40:18Z"},{"alias_kind":"pith_short_8","alias_value":"C66EL4E3","created_at":"2026-07-05T03:40:18Z"}],"graph_snapshots":[{"event_id":"sha256:cd16b67426fae0bb080da6c175284bc5c2e1db31b9968007ebaf72182a4d8ac9","target":"graph","created_at":"2026-07-05T03:40:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2103.04796/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Here we apply hyperspectral bright field imaging to collect computed tomographic images with excellent energy resolution (800 eV), applying it for the first time to map the distribution of stain in a fixed biological sample through its characteristic K-edge. Conventionally, because the photons detected at each pixel are distributed across as many as 200 energy channels, energy-selective images are characterised by low count-rates and poor signal-to-noise ratio. This means high X-ray exposures, long scan times and high doses are required to image unique spectral markers. Here, we achieve high q","authors_text":"Edoardo Pasca, Evangelos Papoutsellis, Evelina Ametova, Gemma Fardell, Jakob S. J{\\o}rgensen, Philip J. Withers, Robert J. Cernik, Ryan Warr, Stephan Handschuh","cross_cats":["eess.IV"],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-03-08T14:46:41Z","title":"Enhanced hyperspectral tomography for bioimaging by spatiospectral reconstruction"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2103.04796","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:c44ce25820a903fc845b64c548b2d5cb8300bbaf02461398e73b4354d8fdd0b1","target":"record","created_at":"2026-07-05T03:40:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"f54a55f0d451fbb9344e36529948c15cb2814faea96d29bc728af3e91c897c17","cross_cats_sorted":["eess.IV"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-03-08T14:46:41Z","title_canon_sha256":"975301f5a5b8b3b8b1451c67351566492eed14caea6b6a7ec9ab16c1c727e8b8"},"schema_version":"1.0","source":{"id":"2103.04796","kind":"arxiv","version":1}},"canonical_sha256":"17bc45f09b35ff49f0c498e3fe46a68f5f8804ca64bbfdbc9165c178ff08c31f","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"17bc45f09b35ff49f0c498e3fe46a68f5f8804ca64bbfdbc9165c178ff08c31f","first_computed_at":"2026-07-05T03:40:18.566827Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T03:40:18.566827Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"X8vfbr4uTnk9JJWJ5EZo7G2VhOXMP4QsBVSsfisZ2ZvWmRJODRbKbPCOpNnMf/ytnwvdajTo5eOfbajWUmGvBQ==","signature_status":"signed_v1","signed_at":"2026-07-05T03:40:18.567234Z","signed_message":"canonical_sha256_bytes"},"source_id":"2103.04796","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:c44ce25820a903fc845b64c548b2d5cb8300bbaf02461398e73b4354d8fdd0b1","sha256:cd16b67426fae0bb080da6c175284bc5c2e1db31b9968007ebaf72182a4d8ac9"],"state_sha256":"c3748075dfa490e45c92686c4e2c19510fc6a54853b9b909067e0e668d92a67b"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Lss0r32ahTUSyzDi2zPJU+Khque4AADHflRRtyUU0nU+2hf/h9MR2zRfcleyzy6sv2uPVfXA7zi6nFDl8BSYBg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-13T06:34:05.434236Z","bundle_sha256":"19363477b4931528f46a92adf6bd5cd0d8442d9893c406a38466a5c77d3c77e6"}}