{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:CEBTKKA3AORJ3NA47RKPFOYJLB","short_pith_number":"pith:CEBTKKA3","canonical_record":{"source":{"id":"1903.07478","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2019-03-18T14:36:00Z","cross_cats_sorted":[],"title_canon_sha256":"4ded1fbab9d228db66dd3adab16f177af55c9194dab5b34de3a1c78a7beabeb3","abstract_canon_sha256":"cca083cb5e7d0229f25193fd87bbc0bd6570ea906a9e38f4e84833fe3492903e"},"schema_version":"1.0"},"canonical_sha256":"110335281b03a29db41cfc54f2bb09586d175468b1fff7d33b91a1eccfd47aaa","source":{"kind":"arxiv","id":"1903.07478","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1903.07478","created_at":"2026-05-17T23:51:01Z"},{"alias_kind":"arxiv_version","alias_value":"1903.07478v1","created_at":"2026-05-17T23:51:01Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1903.07478","created_at":"2026-05-17T23:51:01Z"},{"alias_kind":"pith_short_12","alias_value":"CEBTKKA3AORJ","created_at":"2026-05-18T12:33:12Z"},{"alias_kind":"pith_short_16","alias_value":"CEBTKKA3AORJ3NA4","created_at":"2026-05-18T12:33:12Z"},{"alias_kind":"pith_short_8","alias_value":"CEBTKKA3","created_at":"2026-05-18T12:33:12Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:CEBTKKA3AORJ3NA47RKPFOYJLB","target":"record","payload":{"canonical_record":{"source":{"id":"1903.07478","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2019-03-18T14:36:00Z","cross_cats_sorted":[],"title_canon_sha256":"4ded1fbab9d228db66dd3adab16f177af55c9194dab5b34de3a1c78a7beabeb3","abstract_canon_sha256":"cca083cb5e7d0229f25193fd87bbc0bd6570ea906a9e38f4e84833fe3492903e"},"schema_version":"1.0"},"canonical_sha256":"110335281b03a29db41cfc54f2bb09586d175468b1fff7d33b91a1eccfd47aaa","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:51:01.308763Z","signature_b64":"Ylwj1k7hPZtZwOw6vrd7guv8jukidIWmDKuxeidek7kvbAerXGCnjQVLGbeZW/BeW2Su8H6OZT5FUF4CxfsPAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"110335281b03a29db41cfc54f2bb09586d175468b1fff7d33b91a1eccfd47aaa","last_reissued_at":"2026-05-17T23:51:01.308300Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:51:01.308300Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1903.07478","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:51:01Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"/2omTl7spfQLWHNaesx+5deVQieVlo3XZ2jmW6gUxBni+ZyKoMv7D7XtTcZbxLpWxjFY864WqETuB1TaUAHyCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-08T11:58:21.683829Z"},"content_sha256":"b97e2367cf6c4bac51ea16b35b4c94c0e1bab10ad8b5100077b1030d3c40ce90","schema_version":"1.0","event_id":"sha256:b97e2367cf6c4bac51ea16b35b4c94c0e1bab10ad8b5100077b1030d3c40ce90"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:CEBTKKA3AORJ3NA47RKPFOYJLB","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Neurovascular coupling: insights from multi-modal dynamic causal modelling of fMRI and MEG","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.QM","authors_text":"Amirhossein Jafarian, Hayriye Cagnan, Karl J. Friston, Peter Zeidman, Vladimir Litvak","submitted_at":"2019-03-18T14:36:00Z","abstract_excerpt":"This technical note presents a framework for investigating the underlying mechanisms of neurovascular coupling in the human brain using multi-modal magnetoencephalography (MEG) and functional magnetic resonance (fMRI) neuroimaging data. This amounts to estimating the evidence for several biologically informed models of neurovascular coupling using variational Bayesian methods and selecting the most plausible explanation using Bayesian model comparison. First, fMRI data is used to localise active neuronal sources. The coordinates of neuronal sources are then used as priors in the specification "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1903.07478","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:51:01Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"QzSXtc+DNSBhfqhRDcuSSu/ju/s3jH6Uso37TdpsJi1i7jZLBYRalYzn9Nk+hoMRZKG2sbG1pzGxllifCSYCBQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-08T11:58:21.684508Z"},"content_sha256":"e964096b5f83bf1afe270b01feff7c8ee8c3adf68e1d6660bd9da215661efc4c","schema_version":"1.0","event_id":"sha256:e964096b5f83bf1afe270b01feff7c8ee8c3adf68e1d6660bd9da215661efc4c"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/CEBTKKA3AORJ3NA47RKPFOYJLB/bundle.json","state_url":"https://pith.science/pith/CEBTKKA3AORJ3NA47RKPFOYJLB/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/CEBTKKA3AORJ3NA47RKPFOYJLB/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-08T11:58:21Z","links":{"resolver":"https://pith.science/pith/CEBTKKA3AORJ3NA47RKPFOYJLB","bundle":"https://pith.science/pith/CEBTKKA3AORJ3NA47RKPFOYJLB/bundle.json","state":"https://pith.science/pith/CEBTKKA3AORJ3NA47RKPFOYJLB/state.json","well_known_bundle":"https://pith.science/.well-known/pith/CEBTKKA3AORJ3NA47RKPFOYJLB/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:CEBTKKA3AORJ3NA47RKPFOYJLB","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"cca083cb5e7d0229f25193fd87bbc0bd6570ea906a9e38f4e84833fe3492903e","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2019-03-18T14:36:00Z","title_canon_sha256":"4ded1fbab9d228db66dd3adab16f177af55c9194dab5b34de3a1c78a7beabeb3"},"schema_version":"1.0","source":{"id":"1903.07478","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1903.07478","created_at":"2026-05-17T23:51:01Z"},{"alias_kind":"arxiv_version","alias_value":"1903.07478v1","created_at":"2026-05-17T23:51:01Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1903.07478","created_at":"2026-05-17T23:51:01Z"},{"alias_kind":"pith_short_12","alias_value":"CEBTKKA3AORJ","created_at":"2026-05-18T12:33:12Z"},{"alias_kind":"pith_short_16","alias_value":"CEBTKKA3AORJ3NA4","created_at":"2026-05-18T12:33:12Z"},{"alias_kind":"pith_short_8","alias_value":"CEBTKKA3","created_at":"2026-05-18T12:33:12Z"}],"graph_snapshots":[{"event_id":"sha256:e964096b5f83bf1afe270b01feff7c8ee8c3adf68e1d6660bd9da215661efc4c","target":"graph","created_at":"2026-05-17T23:51:01Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"This technical note presents a framework for investigating the underlying mechanisms of neurovascular coupling in the human brain using multi-modal magnetoencephalography (MEG) and functional magnetic resonance (fMRI) neuroimaging data. This amounts to estimating the evidence for several biologically informed models of neurovascular coupling using variational Bayesian methods and selecting the most plausible explanation using Bayesian model comparison. First, fMRI data is used to localise active neuronal sources. The coordinates of neuronal sources are then used as priors in the specification ","authors_text":"Amirhossein Jafarian, Hayriye Cagnan, Karl J. Friston, Peter Zeidman, Vladimir Litvak","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2019-03-18T14:36:00Z","title":"Neurovascular coupling: insights from multi-modal dynamic causal modelling of fMRI and MEG"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1903.07478","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:b97e2367cf6c4bac51ea16b35b4c94c0e1bab10ad8b5100077b1030d3c40ce90","target":"record","created_at":"2026-05-17T23:51:01Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"cca083cb5e7d0229f25193fd87bbc0bd6570ea906a9e38f4e84833fe3492903e","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2019-03-18T14:36:00Z","title_canon_sha256":"4ded1fbab9d228db66dd3adab16f177af55c9194dab5b34de3a1c78a7beabeb3"},"schema_version":"1.0","source":{"id":"1903.07478","kind":"arxiv","version":1}},"canonical_sha256":"110335281b03a29db41cfc54f2bb09586d175468b1fff7d33b91a1eccfd47aaa","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"110335281b03a29db41cfc54f2bb09586d175468b1fff7d33b91a1eccfd47aaa","first_computed_at":"2026-05-17T23:51:01.308300Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:51:01.308300Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"Ylwj1k7hPZtZwOw6vrd7guv8jukidIWmDKuxeidek7kvbAerXGCnjQVLGbeZW/BeW2Su8H6OZT5FUF4CxfsPAg==","signature_status":"signed_v1","signed_at":"2026-05-17T23:51:01.308763Z","signed_message":"canonical_sha256_bytes"},"source_id":"1903.07478","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:b97e2367cf6c4bac51ea16b35b4c94c0e1bab10ad8b5100077b1030d3c40ce90","sha256:e964096b5f83bf1afe270b01feff7c8ee8c3adf68e1d6660bd9da215661efc4c"],"state_sha256":"dc022f12d40c5de7ea2cb450ddc336d6dc46857bd8cc2559ae8158b9882ffaef"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"BT/+Iin9ReRGUdrypEaYlokRzaMj7vx0EfTfhZfhBBWpYsKFxo8Y1eVE5XzCsAqvYVt5nZjyi+RJEUAZQqLOBg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-08T11:58:21.687991Z","bundle_sha256":"3c3a0c92e9a5f8c50558651d9228a4165ee6861d28b5c8b840afefb0f1733b32"}}