{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:CKMIQUNI53PPGYLOCWTQMMDXFZ","short_pith_number":"pith:CKMIQUNI","canonical_record":{"source":{"id":"1809.11055","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-09-28T14:24:58Z","cross_cats_sorted":[],"title_canon_sha256":"918af3a8bb6a46070f50f3da8ca1ae1091e86e035ed8225fc44d10a4b4764f53","abstract_canon_sha256":"895bfb324e6bdaf0322c94aa3bdfd45128cbbdf992551afe4a74960c9fbd2d36"},"schema_version":"1.0"},"canonical_sha256":"12988851a8eedef3616e15a70630772e708bfe3c15bafd8c37a0c1cca30ef5c3","source":{"kind":"arxiv","id":"1809.11055","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1809.11055","created_at":"2026-05-17T23:53:26Z"},{"alias_kind":"arxiv_version","alias_value":"1809.11055v1","created_at":"2026-05-17T23:53:26Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1809.11055","created_at":"2026-05-17T23:53:26Z"},{"alias_kind":"pith_short_12","alias_value":"CKMIQUNI53PP","created_at":"2026-05-18T12:32:16Z"},{"alias_kind":"pith_short_16","alias_value":"CKMIQUNI53PPGYLO","created_at":"2026-05-18T12:32:16Z"},{"alias_kind":"pith_short_8","alias_value":"CKMIQUNI","created_at":"2026-05-18T12:32:16Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:CKMIQUNI53PPGYLOCWTQMMDXFZ","target":"record","payload":{"canonical_record":{"source":{"id":"1809.11055","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-09-28T14:24:58Z","cross_cats_sorted":[],"title_canon_sha256":"918af3a8bb6a46070f50f3da8ca1ae1091e86e035ed8225fc44d10a4b4764f53","abstract_canon_sha256":"895bfb324e6bdaf0322c94aa3bdfd45128cbbdf992551afe4a74960c9fbd2d36"},"schema_version":"1.0"},"canonical_sha256":"12988851a8eedef3616e15a70630772e708bfe3c15bafd8c37a0c1cca30ef5c3","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:53:26.539582Z","signature_b64":"J3MicI051dWv/MqmbqatopCHfbCaMwjG/Bw/q1tdxvmNO/rE+CQdMTZNiwJfqlIa8azScBWNDqLr3dR7vaa4Bw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"12988851a8eedef3616e15a70630772e708bfe3c15bafd8c37a0c1cca30ef5c3","last_reissued_at":"2026-05-17T23:53:26.539082Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:53:26.539082Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1809.11055","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:53:26Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"TvCTya0xV9xhCNvXvKfDvnU2awxNa+1W9pIHM5v0RcHMm7P5IDrBjKdD5eylMe9jNOxftIMZnh7EIOZrofzjCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-02T07:50:15.378403Z"},"content_sha256":"d26e9ac7a769a66cb6ecddefe01e79b00ed27ea8f5eb5e97b643e936cf17772d","schema_version":"1.0","event_id":"sha256:d26e9ac7a769a66cb6ecddefe01e79b00ed27ea8f5eb5e97b643e936cf17772d"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:CKMIQUNI53PPGYLOCWTQMMDXFZ","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Analysis of time-profiles with in-beam PET monitoring in charged particle therapy","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.med-ph","authors_text":"A.C. Kraan, A. Del Guerra, A. Ferrari, A. Topi, D. Krzempek, G. Battistoni, G. Sportelli, K. Skowronska, M.G. Bisogni, M. Morrocchi, N. Belcari, N. Camarlinghi, P. Olko, P. Sala, R. Kopec, S. Muraro, V. Rosso","submitted_at":"2018-09-28T14:24:58Z","abstract_excerpt":"Background: Treatment verification with PET imaging in charged particle therapy is conventionally done by comparing measurements of spatial distributions with Monte Carlo (MC) predictions. However, decay curves can provide additional independent information about the treatment and the irradiated tissue. Most studies performed so far focus on long time intervals. Here we investigate the reliability of MC predictions of space and time (decay rate) profiles shortly after irradiation, and we show how the decay rates can give an indication about the elements of which the phantom is made up.\n  Metho"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1809.11055","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:53:26Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"KrwnJJJjoE3rP3PIJGlZdnKjGeQVMLHP58QXqTvhIeulfB8rq9XYbTSvvO+t62bn+43xfymKoMuTFs/xEq8MBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-02T07:50:15.378755Z"},"content_sha256":"36ec5e074bc06dcdd1e623ac2f6dd871609bcb89bde8af7c3d2704f0d0ce9d9c","schema_version":"1.0","event_id":"sha256:36ec5e074bc06dcdd1e623ac2f6dd871609bcb89bde8af7c3d2704f0d0ce9d9c"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/CKMIQUNI53PPGYLOCWTQMMDXFZ/bundle.json","state_url":"https://pith.science/pith/CKMIQUNI53PPGYLOCWTQMMDXFZ/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/CKMIQUNI53PPGYLOCWTQMMDXFZ/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-02T07:50:15Z","links":{"resolver":"https://pith.science/pith/CKMIQUNI53PPGYLOCWTQMMDXFZ","bundle":"https://pith.science/pith/CKMIQUNI53PPGYLOCWTQMMDXFZ/bundle.json","state":"https://pith.science/pith/CKMIQUNI53PPGYLOCWTQMMDXFZ/state.json","well_known_bundle":"https://pith.science/.well-known/pith/CKMIQUNI53PPGYLOCWTQMMDXFZ/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:CKMIQUNI53PPGYLOCWTQMMDXFZ","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"895bfb324e6bdaf0322c94aa3bdfd45128cbbdf992551afe4a74960c9fbd2d36","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-09-28T14:24:58Z","title_canon_sha256":"918af3a8bb6a46070f50f3da8ca1ae1091e86e035ed8225fc44d10a4b4764f53"},"schema_version":"1.0","source":{"id":"1809.11055","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1809.11055","created_at":"2026-05-17T23:53:26Z"},{"alias_kind":"arxiv_version","alias_value":"1809.11055v1","created_at":"2026-05-17T23:53:26Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1809.11055","created_at":"2026-05-17T23:53:26Z"},{"alias_kind":"pith_short_12","alias_value":"CKMIQUNI53PP","created_at":"2026-05-18T12:32:16Z"},{"alias_kind":"pith_short_16","alias_value":"CKMIQUNI53PPGYLO","created_at":"2026-05-18T12:32:16Z"},{"alias_kind":"pith_short_8","alias_value":"CKMIQUNI","created_at":"2026-05-18T12:32:16Z"}],"graph_snapshots":[{"event_id":"sha256:36ec5e074bc06dcdd1e623ac2f6dd871609bcb89bde8af7c3d2704f0d0ce9d9c","target":"graph","created_at":"2026-05-17T23:53:26Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Background: Treatment verification with PET imaging in charged particle therapy is conventionally done by comparing measurements of spatial distributions with Monte Carlo (MC) predictions. However, decay curves can provide additional independent information about the treatment and the irradiated tissue. Most studies performed so far focus on long time intervals. Here we investigate the reliability of MC predictions of space and time (decay rate) profiles shortly after irradiation, and we show how the decay rates can give an indication about the elements of which the phantom is made up.\n  Metho","authors_text":"A.C. Kraan, A. Del Guerra, A. Ferrari, A. Topi, D. Krzempek, G. Battistoni, G. Sportelli, K. Skowronska, M.G. Bisogni, M. Morrocchi, N. Belcari, N. Camarlinghi, P. Olko, P. Sala, R. Kopec, S. Muraro, V. Rosso","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-09-28T14:24:58Z","title":"Analysis of time-profiles with in-beam PET monitoring in charged particle therapy"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1809.11055","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:d26e9ac7a769a66cb6ecddefe01e79b00ed27ea8f5eb5e97b643e936cf17772d","target":"record","created_at":"2026-05-17T23:53:26Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"895bfb324e6bdaf0322c94aa3bdfd45128cbbdf992551afe4a74960c9fbd2d36","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-09-28T14:24:58Z","title_canon_sha256":"918af3a8bb6a46070f50f3da8ca1ae1091e86e035ed8225fc44d10a4b4764f53"},"schema_version":"1.0","source":{"id":"1809.11055","kind":"arxiv","version":1}},"canonical_sha256":"12988851a8eedef3616e15a70630772e708bfe3c15bafd8c37a0c1cca30ef5c3","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"12988851a8eedef3616e15a70630772e708bfe3c15bafd8c37a0c1cca30ef5c3","first_computed_at":"2026-05-17T23:53:26.539082Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:53:26.539082Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"J3MicI051dWv/MqmbqatopCHfbCaMwjG/Bw/q1tdxvmNO/rE+CQdMTZNiwJfqlIa8azScBWNDqLr3dR7vaa4Bw==","signature_status":"signed_v1","signed_at":"2026-05-17T23:53:26.539582Z","signed_message":"canonical_sha256_bytes"},"source_id":"1809.11055","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:d26e9ac7a769a66cb6ecddefe01e79b00ed27ea8f5eb5e97b643e936cf17772d","sha256:36ec5e074bc06dcdd1e623ac2f6dd871609bcb89bde8af7c3d2704f0d0ce9d9c"],"state_sha256":"07f1ee7e4f971098abc8bbc9c80d5376855e4aeadcf2756e2925d2dc57c12132"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"XyJ2qZJIs2MDrvYCK/YdQMFfEC2WO3wRuY0C6mpf0Z9tdp1ursMd/D8BV5BDLSSspaQ4r7N51E+Wn0Xb7uqtCg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-02T07:50:15.380696Z","bundle_sha256":"6b81ee6227d6eb5af2aaf6e27c9635a9b18d143b47fcce7b091688e8e06ae09f"}}