{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:CQKCIF4WBMDTH234SINZPBBLC3","short_pith_number":"pith:CQKCIF4W","canonical_record":{"source":{"id":"1608.04444","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.stat-mech","submitted_at":"2016-08-16T00:16:01Z","cross_cats_sorted":[],"title_canon_sha256":"4d8855cb8e347e04967d63d37403806d1aeb94a3773c3324ea2f740da2ef6fac","abstract_canon_sha256":"c95c80067c27f8a9f33b87bd34379746bd9689ead152d54dc7d276a8679244fc"},"schema_version":"1.0"},"canonical_sha256":"14142417960b0733eb7c921b97842b16c54e26ffe2952f945abae0f9a621f4d9","source":{"kind":"arxiv","id":"1608.04444","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1608.04444","created_at":"2026-05-18T01:00:19Z"},{"alias_kind":"arxiv_version","alias_value":"1608.04444v2","created_at":"2026-05-18T01:00:19Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1608.04444","created_at":"2026-05-18T01:00:19Z"},{"alias_kind":"pith_short_12","alias_value":"CQKCIF4WBMDT","created_at":"2026-05-18T12:30:09Z"},{"alias_kind":"pith_short_16","alias_value":"CQKCIF4WBMDTH234","created_at":"2026-05-18T12:30:09Z"},{"alias_kind":"pith_short_8","alias_value":"CQKCIF4W","created_at":"2026-05-18T12:30:09Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:CQKCIF4WBMDTH234SINZPBBLC3","target":"record","payload":{"canonical_record":{"source":{"id":"1608.04444","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.stat-mech","submitted_at":"2016-08-16T00:16:01Z","cross_cats_sorted":[],"title_canon_sha256":"4d8855cb8e347e04967d63d37403806d1aeb94a3773c3324ea2f740da2ef6fac","abstract_canon_sha256":"c95c80067c27f8a9f33b87bd34379746bd9689ead152d54dc7d276a8679244fc"},"schema_version":"1.0"},"canonical_sha256":"14142417960b0733eb7c921b97842b16c54e26ffe2952f945abae0f9a621f4d9","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:00:19.068838Z","signature_b64":"GxKd/poAh1i5OAsCkVn1vp9j+pRvq1yOOTYhZkNeXfOEwNz6MoCHdnAwmdf0QykPc6Mskm/dhLFgZaQkEmaICw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"14142417960b0733eb7c921b97842b16c54e26ffe2952f945abae0f9a621f4d9","last_reissued_at":"2026-05-18T01:00:19.068182Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:00:19.068182Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1608.04444","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:00:19Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Z6oLyoRKYFRH7s9/hhn7POMkamgmaGz56nvQFScjAUXE+Le+2lTC6bgUJKmLYnzr34rtbWalK4aWS0WQqEc4CA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-20T10:44:10.303409Z"},"content_sha256":"224c4b66e3b8cf0131b6056a6a3d96d175e7138a5df63c4f872458bf2c8ec8df","schema_version":"1.0","event_id":"sha256:224c4b66e3b8cf0131b6056a6a3d96d175e7138a5df63c4f872458bf2c8ec8df"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:CQKCIF4WBMDTH234SINZPBBLC3","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Thermodynamic geometry of minimum-dissipation driven barrier crossing","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"cond-mat.stat-mech","authors_text":"David A. Sivak, Gavin E. Crooks","submitted_at":"2016-08-16T00:16:01Z","abstract_excerpt":"We explore the thermodynamic geometry of a simple system that models the bistable dynamics of nucleic acid hairpins in single molecule force-extension experiments. Near equilibrium, optimal (minimum-dissipation) driving protocols are governed by a generalized linear response friction coefficient. Our analysis and simulations demonstrate that the friction coefficient of the driving protocols is sharply peaked at the interface between metastable regions, which leads to minimum-dissipation protocols that drive rapidly within a metastable basin, but then linger longest at the interface, giving the"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1608.04444","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:00:19Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"RnGYjklT+IAK2gCnfI8csnAJ6uPSruCnjUafd7VhWdTmq2GvaW1BVzpLnQvnzTYLhOOBqBnzqn7p4QluklLJAQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-20T10:44:10.303757Z"},"content_sha256":"2b1d5972015787a12f36834a0e5d7b8f94953dc66692b51a4d85120133582af1","schema_version":"1.0","event_id":"sha256:2b1d5972015787a12f36834a0e5d7b8f94953dc66692b51a4d85120133582af1"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/CQKCIF4WBMDTH234SINZPBBLC3/bundle.json","state_url":"https://pith.science/pith/CQKCIF4WBMDTH234SINZPBBLC3/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/CQKCIF4WBMDTH234SINZPBBLC3/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-20T10:44:10Z","links":{"resolver":"https://pith.science/pith/CQKCIF4WBMDTH234SINZPBBLC3","bundle":"https://pith.science/pith/CQKCIF4WBMDTH234SINZPBBLC3/bundle.json","state":"https://pith.science/pith/CQKCIF4WBMDTH234SINZPBBLC3/state.json","well_known_bundle":"https://pith.science/.well-known/pith/CQKCIF4WBMDTH234SINZPBBLC3/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:CQKCIF4WBMDTH234SINZPBBLC3","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"c95c80067c27f8a9f33b87bd34379746bd9689ead152d54dc7d276a8679244fc","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.stat-mech","submitted_at":"2016-08-16T00:16:01Z","title_canon_sha256":"4d8855cb8e347e04967d63d37403806d1aeb94a3773c3324ea2f740da2ef6fac"},"schema_version":"1.0","source":{"id":"1608.04444","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1608.04444","created_at":"2026-05-18T01:00:19Z"},{"alias_kind":"arxiv_version","alias_value":"1608.04444v2","created_at":"2026-05-18T01:00:19Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1608.04444","created_at":"2026-05-18T01:00:19Z"},{"alias_kind":"pith_short_12","alias_value":"CQKCIF4WBMDT","created_at":"2026-05-18T12:30:09Z"},{"alias_kind":"pith_short_16","alias_value":"CQKCIF4WBMDTH234","created_at":"2026-05-18T12:30:09Z"},{"alias_kind":"pith_short_8","alias_value":"CQKCIF4W","created_at":"2026-05-18T12:30:09Z"}],"graph_snapshots":[{"event_id":"sha256:2b1d5972015787a12f36834a0e5d7b8f94953dc66692b51a4d85120133582af1","target":"graph","created_at":"2026-05-18T01:00:19Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"We explore the thermodynamic geometry of a simple system that models the bistable dynamics of nucleic acid hairpins in single molecule force-extension experiments. Near equilibrium, optimal (minimum-dissipation) driving protocols are governed by a generalized linear response friction coefficient. Our analysis and simulations demonstrate that the friction coefficient of the driving protocols is sharply peaked at the interface between metastable regions, which leads to minimum-dissipation protocols that drive rapidly within a metastable basin, but then linger longest at the interface, giving the","authors_text":"David A. Sivak, Gavin E. Crooks","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.stat-mech","submitted_at":"2016-08-16T00:16:01Z","title":"Thermodynamic geometry of minimum-dissipation driven barrier crossing"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1608.04444","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:224c4b66e3b8cf0131b6056a6a3d96d175e7138a5df63c4f872458bf2c8ec8df","target":"record","created_at":"2026-05-18T01:00:19Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"c95c80067c27f8a9f33b87bd34379746bd9689ead152d54dc7d276a8679244fc","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.stat-mech","submitted_at":"2016-08-16T00:16:01Z","title_canon_sha256":"4d8855cb8e347e04967d63d37403806d1aeb94a3773c3324ea2f740da2ef6fac"},"schema_version":"1.0","source":{"id":"1608.04444","kind":"arxiv","version":2}},"canonical_sha256":"14142417960b0733eb7c921b97842b16c54e26ffe2952f945abae0f9a621f4d9","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"14142417960b0733eb7c921b97842b16c54e26ffe2952f945abae0f9a621f4d9","first_computed_at":"2026-05-18T01:00:19.068182Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:00:19.068182Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"GxKd/poAh1i5OAsCkVn1vp9j+pRvq1yOOTYhZkNeXfOEwNz6MoCHdnAwmdf0QykPc6Mskm/dhLFgZaQkEmaICw==","signature_status":"signed_v1","signed_at":"2026-05-18T01:00:19.068838Z","signed_message":"canonical_sha256_bytes"},"source_id":"1608.04444","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:224c4b66e3b8cf0131b6056a6a3d96d175e7138a5df63c4f872458bf2c8ec8df","sha256:2b1d5972015787a12f36834a0e5d7b8f94953dc66692b51a4d85120133582af1"],"state_sha256":"1731cc2cad2ae3b3ed99de3bb24b4dc3576e3fb65107edc991279f1cdc4f59af"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"u3iqPJP/3MQD5noexv2+h4KfjIeQM/gBtFVa6BA81GGF3uXDtEa2ERlN5yD1QBxTYU/DW/Qh6rmd23S5SoKjDA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-20T10:44:10.305857Z","bundle_sha256":"9d2cec4a97be7dcc48463c97b5c132cf2ef567dd3e13651104f631fc3919e46b"}}