{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2023:CRLS7DLK7TT3TVMG2TZX2MSZSF","short_pith_number":"pith:CRLS7DLK","canonical_record":{"source":{"id":"2310.16716","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2023-10-25T15:39:17Z","cross_cats_sorted":[],"title_canon_sha256":"fc185bcc784a676ab7c1f92c277cd2c6719463fbe0f14ee15d72dc480bff9d94","abstract_canon_sha256":"b2dc5bd08f4b8d3c47f83c5caee4cbb96ce0ffb82dd43827e120edd289b0393f"},"schema_version":"1.0"},"canonical_sha256":"14572f8d6afce7b9d586d4f37d3259917eafbfbfcb0f598ec66b762eeacfd2b1","source":{"kind":"arxiv","id":"2310.16716","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2310.16716","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"arxiv_version","alias_value":"2310.16716v1","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2310.16716","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"pith_short_12","alias_value":"CRLS7DLK7TT3","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"pith_short_16","alias_value":"CRLS7DLK7TT3TVMG","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"pith_short_8","alias_value":"CRLS7DLK","created_at":"2026-07-05T07:05:01Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2023:CRLS7DLK7TT3TVMG2TZX2MSZSF","target":"record","payload":{"canonical_record":{"source":{"id":"2310.16716","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2023-10-25T15:39:17Z","cross_cats_sorted":[],"title_canon_sha256":"fc185bcc784a676ab7c1f92c277cd2c6719463fbe0f14ee15d72dc480bff9d94","abstract_canon_sha256":"b2dc5bd08f4b8d3c47f83c5caee4cbb96ce0ffb82dd43827e120edd289b0393f"},"schema_version":"1.0"},"canonical_sha256":"14572f8d6afce7b9d586d4f37d3259917eafbfbfcb0f598ec66b762eeacfd2b1","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T07:05:01.964147Z","signature_b64":"fLsThtiVhrsodNaUaX8p83aQ1F8iD0ll0ZojNzvqy77flSLWgx5RPxW9x5p4AbSldeU0hsq28zjUG0pFa1P1Bg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"14572f8d6afce7b9d586d4f37d3259917eafbfbfcb0f598ec66b762eeacfd2b1","last_reissued_at":"2026-07-05T07:05:01.963678Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T07:05:01.963678Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2310.16716","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T07:05:01Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"+Oej0NLl5YSn9D6W+sXSywMsmbqsRMzOmSN9M36FHBryyNYbvA8+V+x2d5nk0HdOQAeICWfujXi2OQlcfX0eBg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-21T21:41:47.114606Z"},"content_sha256":"0e14d846c27fa1e310d7ca39ed9097d881cc631d6b999cb2664bb07d83eb75ed","schema_version":"1.0","event_id":"sha256:0e14d846c27fa1e310d7ca39ed9097d881cc631d6b999cb2664bb07d83eb75ed"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2023:CRLS7DLK7TT3TVMG2TZX2MSZSF","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Best practices for the manual curation of Intrinsically Disordered Proteins in DisProt","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.BM","authors_text":"Anastasia Chasapi, Damiano Piovesan, Emanuela Leonardi, Federica Quaglia, Maria Cristina Aspromonte, Maria Victoria Nugnes, Silvio C.E. Tosatto","submitted_at":"2023-10-25T15:39:17Z","abstract_excerpt":"The DisProt database is a significant resource containing manually curated data on experimentally validated intrinsically disordered proteins (IDPs) and regions (IDRs) from the literature. Developed in 2005, its primary goal was to collect structural and functional information into proteins that lack a fixed three-dimensional (3D) structure. Today, DisProt has evolved into a major repository that not only collects experimental data but also contributes significantly to our understanding of the IDPs/IDRs roles in various biological processes, such as autophagy or the life cycle mechanisms in vi"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2310.16716","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2310.16716/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T07:05:01Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"ux3aTu25GoeCl3hmSMLQoLoB6JLleIFXJyEwf+ei6s8977KJmd0REvGqc4SwxsIeL8906sb3XbMTUb2LbsIXCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-21T21:41:47.115106Z"},"content_sha256":"a97e538a8104292113d9f06e73431f209f0f0d79a664527760d1efdd71900d11","schema_version":"1.0","event_id":"sha256:a97e538a8104292113d9f06e73431f209f0f0d79a664527760d1efdd71900d11"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/CRLS7DLK7TT3TVMG2TZX2MSZSF/bundle.json","state_url":"https://pith.science/pith/CRLS7DLK7TT3TVMG2TZX2MSZSF/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/CRLS7DLK7TT3TVMG2TZX2MSZSF/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-21T21:41:47Z","links":{"resolver":"https://pith.science/pith/CRLS7DLK7TT3TVMG2TZX2MSZSF","bundle":"https://pith.science/pith/CRLS7DLK7TT3TVMG2TZX2MSZSF/bundle.json","state":"https://pith.science/pith/CRLS7DLK7TT3TVMG2TZX2MSZSF/state.json","well_known_bundle":"https://pith.science/.well-known/pith/CRLS7DLK7TT3TVMG2TZX2MSZSF/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2023:CRLS7DLK7TT3TVMG2TZX2MSZSF","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"b2dc5bd08f4b8d3c47f83c5caee4cbb96ce0ffb82dd43827e120edd289b0393f","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2023-10-25T15:39:17Z","title_canon_sha256":"fc185bcc784a676ab7c1f92c277cd2c6719463fbe0f14ee15d72dc480bff9d94"},"schema_version":"1.0","source":{"id":"2310.16716","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2310.16716","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"arxiv_version","alias_value":"2310.16716v1","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2310.16716","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"pith_short_12","alias_value":"CRLS7DLK7TT3","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"pith_short_16","alias_value":"CRLS7DLK7TT3TVMG","created_at":"2026-07-05T07:05:01Z"},{"alias_kind":"pith_short_8","alias_value":"CRLS7DLK","created_at":"2026-07-05T07:05:01Z"}],"graph_snapshots":[{"event_id":"sha256:a97e538a8104292113d9f06e73431f209f0f0d79a664527760d1efdd71900d11","target":"graph","created_at":"2026-07-05T07:05:01Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2310.16716/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"The DisProt database is a significant resource containing manually curated data on experimentally validated intrinsically disordered proteins (IDPs) and regions (IDRs) from the literature. Developed in 2005, its primary goal was to collect structural and functional information into proteins that lack a fixed three-dimensional (3D) structure. Today, DisProt has evolved into a major repository that not only collects experimental data but also contributes significantly to our understanding of the IDPs/IDRs roles in various biological processes, such as autophagy or the life cycle mechanisms in vi","authors_text":"Anastasia Chasapi, Damiano Piovesan, Emanuela Leonardi, Federica Quaglia, Maria Cristina Aspromonte, Maria Victoria Nugnes, Silvio C.E. Tosatto","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2023-10-25T15:39:17Z","title":"Best practices for the manual curation of Intrinsically Disordered Proteins in DisProt"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2310.16716","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:0e14d846c27fa1e310d7ca39ed9097d881cc631d6b999cb2664bb07d83eb75ed","target":"record","created_at":"2026-07-05T07:05:01Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"b2dc5bd08f4b8d3c47f83c5caee4cbb96ce0ffb82dd43827e120edd289b0393f","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2023-10-25T15:39:17Z","title_canon_sha256":"fc185bcc784a676ab7c1f92c277cd2c6719463fbe0f14ee15d72dc480bff9d94"},"schema_version":"1.0","source":{"id":"2310.16716","kind":"arxiv","version":1}},"canonical_sha256":"14572f8d6afce7b9d586d4f37d3259917eafbfbfcb0f598ec66b762eeacfd2b1","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"14572f8d6afce7b9d586d4f37d3259917eafbfbfcb0f598ec66b762eeacfd2b1","first_computed_at":"2026-07-05T07:05:01.963678Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T07:05:01.963678Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"fLsThtiVhrsodNaUaX8p83aQ1F8iD0ll0ZojNzvqy77flSLWgx5RPxW9x5p4AbSldeU0hsq28zjUG0pFa1P1Bg==","signature_status":"signed_v1","signed_at":"2026-07-05T07:05:01.964147Z","signed_message":"canonical_sha256_bytes"},"source_id":"2310.16716","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:0e14d846c27fa1e310d7ca39ed9097d881cc631d6b999cb2664bb07d83eb75ed","sha256:a97e538a8104292113d9f06e73431f209f0f0d79a664527760d1efdd71900d11"],"state_sha256":"bb24e1a79dd6d67852453caa639f10c261c87323dd515b527ac76594228ec06a"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Tt8XQ7tEMqZHhqgD6WA+vE8Ee8C8ebfRqFLmI0HbLGOBfkH3y5cxuy42ZERpcmtHo45dsupT3VV5IFzdVzKoCw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-21T21:41:47.120461Z","bundle_sha256":"e8add30d2789399b967024a521731d66f9b2d3cf312e051eab61093d98f42d8f"}}