{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2024:CU5AF7KJOYSZSZEGEIYEQ2PCQM","short_pith_number":"pith:CU5AF7KJ","canonical_record":{"source":{"id":"2408.09171","kind":"arxiv","version":3},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.ET","submitted_at":"2024-08-17T11:31:18Z","cross_cats_sorted":["physics.chem-ph"],"title_canon_sha256":"184b4348c658ec5e1f2bae920b28983dc8a376dc9fdda46b82ca00fce0606705","abstract_canon_sha256":"a165ec11d8fa728e165afd772205a46ac4c4a0eae6606c926b633cddb15e2682"},"schema_version":"1.0"},"canonical_sha256":"153a02fd49762599648622304869e2833c04ff15302f4a2a880890539bef49d2","source":{"kind":"arxiv","id":"2408.09171","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2408.09171","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"arxiv_version","alias_value":"2408.09171v3","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2408.09171","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"pith_short_12","alias_value":"CU5AF7KJOYSZ","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"pith_short_16","alias_value":"CU5AF7KJOYSZSZEG","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"pith_short_8","alias_value":"CU5AF7KJ","created_at":"2026-07-05T11:39:42Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2024:CU5AF7KJOYSZSZEGEIYEQ2PCQM","target":"record","payload":{"canonical_record":{"source":{"id":"2408.09171","kind":"arxiv","version":3},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.ET","submitted_at":"2024-08-17T11:31:18Z","cross_cats_sorted":["physics.chem-ph"],"title_canon_sha256":"184b4348c658ec5e1f2bae920b28983dc8a376dc9fdda46b82ca00fce0606705","abstract_canon_sha256":"a165ec11d8fa728e165afd772205a46ac4c4a0eae6606c926b633cddb15e2682"},"schema_version":"1.0"},"canonical_sha256":"153a02fd49762599648622304869e2833c04ff15302f4a2a880890539bef49d2","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T11:39:42.523865Z","signature_b64":"lbHyyY6yRfGZ91za6OdsnKiGAnOjvdbEgpAxAgWyVkg8jEXtw3oS1WJRoe5Idf2P9p4lS37R5DBEr9dPz4uzDg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"153a02fd49762599648622304869e2833c04ff15302f4a2a880890539bef49d2","last_reissued_at":"2026-07-05T11:39:42.523217Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T11:39:42.523217Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2408.09171","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T11:39:42Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Chu7DS/3s3tHDdHoJxdJS1a4T9PEbBbKrBL9YAVkx3reXUggyeg+GwWwnIDmvhgE6C9wN6kCPWUMA04WoIO7Bw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-08T16:25:04.465353Z"},"content_sha256":"58fb9aee4e7b57a86f04235d856f799444984d92c60b1149d231322be3f45416","schema_version":"1.0","event_id":"sha256:58fb9aee4e7b57a86f04235d856f799444984d92c60b1149d231322be3f45416"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2024:CU5AF7KJOYSZSZEGEIYEQ2PCQM","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Chemputer and Chemputation -- A Universal Chemical Compound Synthesis Machine","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","headline":"","cross_cats":["physics.chem-ph"],"primary_cat":"cs.ET","authors_text":"Abhishek Sharma, Leroy Cronin, Sebastian Pagel","submitted_at":"2024-08-17T11:31:18Z","abstract_excerpt":"Chemputation reframes synthesis as the programmable execution of reaction code on a universally re-configurable hardware graph. Here we prove that a chemputer equipped with a finite, but extensible, set of reagents, catalysts and process conditions, together with a chempiler that maps reaction graphs onto hardware, is universal: it can generate any stable, isolable molecule in finite time and in analytically detectable quantity, provided real-time error correction keeps the per-step fidelity above the threshold set by the molecule's assembly index. The proof is constructed by casting the platf"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2408.09171","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2408.09171/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T11:39:42Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"2oz5AEyPWX1zHz9nXElGROazwYD8rkhaymZrKgPZSP7cxYos2rnnOJmcjwJ8RUx/SdYQh50gWMAyayc4JX5aAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-08T16:25:04.465867Z"},"content_sha256":"b2c9dc17160cf172de96b57fb4f438e2e637445c13637f1c435cd879c13fbe93","schema_version":"1.0","event_id":"sha256:b2c9dc17160cf172de96b57fb4f438e2e637445c13637f1c435cd879c13fbe93"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/CU5AF7KJOYSZSZEGEIYEQ2PCQM/bundle.json","state_url":"https://pith.science/pith/CU5AF7KJOYSZSZEGEIYEQ2PCQM/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/CU5AF7KJOYSZSZEGEIYEQ2PCQM/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-08T16:25:04Z","links":{"resolver":"https://pith.science/pith/CU5AF7KJOYSZSZEGEIYEQ2PCQM","bundle":"https://pith.science/pith/CU5AF7KJOYSZSZEGEIYEQ2PCQM/bundle.json","state":"https://pith.science/pith/CU5AF7KJOYSZSZEGEIYEQ2PCQM/state.json","well_known_bundle":"https://pith.science/.well-known/pith/CU5AF7KJOYSZSZEGEIYEQ2PCQM/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2024:CU5AF7KJOYSZSZEGEIYEQ2PCQM","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"a165ec11d8fa728e165afd772205a46ac4c4a0eae6606c926b633cddb15e2682","cross_cats_sorted":["physics.chem-ph"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.ET","submitted_at":"2024-08-17T11:31:18Z","title_canon_sha256":"184b4348c658ec5e1f2bae920b28983dc8a376dc9fdda46b82ca00fce0606705"},"schema_version":"1.0","source":{"id":"2408.09171","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2408.09171","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"arxiv_version","alias_value":"2408.09171v3","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2408.09171","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"pith_short_12","alias_value":"CU5AF7KJOYSZ","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"pith_short_16","alias_value":"CU5AF7KJOYSZSZEG","created_at":"2026-07-05T11:39:42Z"},{"alias_kind":"pith_short_8","alias_value":"CU5AF7KJ","created_at":"2026-07-05T11:39:42Z"}],"graph_snapshots":[{"event_id":"sha256:b2c9dc17160cf172de96b57fb4f438e2e637445c13637f1c435cd879c13fbe93","target":"graph","created_at":"2026-07-05T11:39:42Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2408.09171/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Chemputation reframes synthesis as the programmable execution of reaction code on a universally re-configurable hardware graph. Here we prove that a chemputer equipped with a finite, but extensible, set of reagents, catalysts and process conditions, together with a chempiler that maps reaction graphs onto hardware, is universal: it can generate any stable, isolable molecule in finite time and in analytically detectable quantity, provided real-time error correction keeps the per-step fidelity above the threshold set by the molecule's assembly index. The proof is constructed by casting the platf","authors_text":"Abhishek Sharma, Leroy Cronin, Sebastian Pagel","cross_cats":["physics.chem-ph"],"headline":"","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.ET","submitted_at":"2024-08-17T11:31:18Z","title":"Chemputer and Chemputation -- A Universal Chemical Compound Synthesis Machine"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2408.09171","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:58fb9aee4e7b57a86f04235d856f799444984d92c60b1149d231322be3f45416","target":"record","created_at":"2026-07-05T11:39:42Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"a165ec11d8fa728e165afd772205a46ac4c4a0eae6606c926b633cddb15e2682","cross_cats_sorted":["physics.chem-ph"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.ET","submitted_at":"2024-08-17T11:31:18Z","title_canon_sha256":"184b4348c658ec5e1f2bae920b28983dc8a376dc9fdda46b82ca00fce0606705"},"schema_version":"1.0","source":{"id":"2408.09171","kind":"arxiv","version":3}},"canonical_sha256":"153a02fd49762599648622304869e2833c04ff15302f4a2a880890539bef49d2","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"153a02fd49762599648622304869e2833c04ff15302f4a2a880890539bef49d2","first_computed_at":"2026-07-05T11:39:42.523217Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T11:39:42.523217Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"lbHyyY6yRfGZ91za6OdsnKiGAnOjvdbEgpAxAgWyVkg8jEXtw3oS1WJRoe5Idf2P9p4lS37R5DBEr9dPz4uzDg==","signature_status":"signed_v1","signed_at":"2026-07-05T11:39:42.523865Z","signed_message":"canonical_sha256_bytes"},"source_id":"2408.09171","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:58fb9aee4e7b57a86f04235d856f799444984d92c60b1149d231322be3f45416","sha256:b2c9dc17160cf172de96b57fb4f438e2e637445c13637f1c435cd879c13fbe93"],"state_sha256":"6bbf0ca62029453322abafae12be802926685267e052507e0e2b01328e51d46e"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"hPEMp/4ErDcRuZPS+tkQbVnnYD43Te3LiNqdgPxeQG/bPr2yKQWnddid0+ZYLjVOIk27yyVUPSYD/4DGyFxxBA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-08T16:25:04.470559Z","bundle_sha256":"63a05d6cd8c1a7f046b5ab032062164803bd1337fdb0b5650224524ff186d9ad"}}