{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2022:D5YLK67XYTPA64RVLECWCTS7NC","short_pith_number":"pith:D5YLK67X","canonical_record":{"source":{"id":"2204.00290","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CL","submitted_at":"2022-04-01T08:45:39Z","cross_cats_sorted":["cs.LG"],"title_canon_sha256":"08802bebfeb280cf6103089821de830f60887e21d2a65ce67b9cd83f65edd201","abstract_canon_sha256":"6add63cd30c2ee15a8b77df5fe4c2efb8c7dabcfae3df7608347978111fdceac"},"schema_version":"1.0"},"canonical_sha256":"1f70b57bf7c4de0f72355905614e5f6892c90ab4ccffffc0f42c942e56127861","source":{"kind":"arxiv","id":"2204.00290","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2204.00290","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"arxiv_version","alias_value":"2204.00290v1","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2204.00290","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"pith_short_12","alias_value":"D5YLK67XYTPA","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"pith_short_16","alias_value":"D5YLK67XYTPA64RV","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"pith_short_8","alias_value":"D5YLK67X","created_at":"2026-07-05T04:10:45Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2022:D5YLK67XYTPA64RVLECWCTS7NC","target":"record","payload":{"canonical_record":{"source":{"id":"2204.00290","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CL","submitted_at":"2022-04-01T08:45:39Z","cross_cats_sorted":["cs.LG"],"title_canon_sha256":"08802bebfeb280cf6103089821de830f60887e21d2a65ce67b9cd83f65edd201","abstract_canon_sha256":"6add63cd30c2ee15a8b77df5fe4c2efb8c7dabcfae3df7608347978111fdceac"},"schema_version":"1.0"},"canonical_sha256":"1f70b57bf7c4de0f72355905614e5f6892c90ab4ccffffc0f42c942e56127861","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T04:10:45.368538Z","signature_b64":"cJPeDsS8djcP5NXeGwrR+pPZOY5T+s7l9dmC9kM1RI6exEuhBXjGd6UUwDre876aC6I0CiHsrpBQfeOG6GUeDQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"1f70b57bf7c4de0f72355905614e5f6892c90ab4ccffffc0f42c942e56127861","last_reissued_at":"2026-07-05T04:10:45.368182Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T04:10:45.368182Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2204.00290","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:10:45Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"GYwr1ojkBJfIOimvBy/wPGx5TXRJa2Hqc57+GgpS9hSg3F8Imcjq4zQbzC3LbNtpSTXxOgLaIO5ZRPTjENCcDA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-16T15:42:12.741221Z"},"content_sha256":"3a7fc0e0c3a0fa42ccea3a827251aedcce8f4420ffbb82b5736e9ea2c8af1b87","schema_version":"1.0","event_id":"sha256:3a7fc0e0c3a0fa42ccea3a827251aedcce8f4420ffbb82b5736e9ea2c8af1b87"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2022:D5YLK67XYTPA64RVLECWCTS7NC","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Predicting Intervention Approval in Clinical Trials through Multi-Document Summarization","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","headline":"","cross_cats":["cs.LG"],"primary_cat":"cs.CL","authors_text":"Georgios Katsimpras, Georgios Paliouras","submitted_at":"2022-04-01T08:45:39Z","abstract_excerpt":"Clinical trials offer a fundamental opportunity to discover new treatments and advance the medical knowledge. However, the uncertainty of the outcome of a trial can lead to unforeseen costs and setbacks. In this study, we propose a new method to predict the effectiveness of an intervention in a clinical trial. Our method relies on generating an informative summary from multiple documents available in the literature about the intervention under study. Specifically, our method first gathers all the abstracts of PubMed articles related to the intervention. Then, an evidence sentence, which convey"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2204.00290","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2204.00290/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T04:10:45Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"QTQX+vCx86TOUhDXSdPYhlS+pGMt77Uvnsk6QnC3rJxEn+y2b4p5OvFc4QF6AxrNA9X5lpodoF8hk0uFi5TjBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-16T15:42:12.741621Z"},"content_sha256":"0153f57609686a041c9844d7aaa8ffa95e68abcea67ddbd99e40a220e97a02cb","schema_version":"1.0","event_id":"sha256:0153f57609686a041c9844d7aaa8ffa95e68abcea67ddbd99e40a220e97a02cb"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/D5YLK67XYTPA64RVLECWCTS7NC/bundle.json","state_url":"https://pith.science/pith/D5YLK67XYTPA64RVLECWCTS7NC/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/D5YLK67XYTPA64RVLECWCTS7NC/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-16T15:42:12Z","links":{"resolver":"https://pith.science/pith/D5YLK67XYTPA64RVLECWCTS7NC","bundle":"https://pith.science/pith/D5YLK67XYTPA64RVLECWCTS7NC/bundle.json","state":"https://pith.science/pith/D5YLK67XYTPA64RVLECWCTS7NC/state.json","well_known_bundle":"https://pith.science/.well-known/pith/D5YLK67XYTPA64RVLECWCTS7NC/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2022:D5YLK67XYTPA64RVLECWCTS7NC","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"6add63cd30c2ee15a8b77df5fe4c2efb8c7dabcfae3df7608347978111fdceac","cross_cats_sorted":["cs.LG"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CL","submitted_at":"2022-04-01T08:45:39Z","title_canon_sha256":"08802bebfeb280cf6103089821de830f60887e21d2a65ce67b9cd83f65edd201"},"schema_version":"1.0","source":{"id":"2204.00290","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2204.00290","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"arxiv_version","alias_value":"2204.00290v1","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2204.00290","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"pith_short_12","alias_value":"D5YLK67XYTPA","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"pith_short_16","alias_value":"D5YLK67XYTPA64RV","created_at":"2026-07-05T04:10:45Z"},{"alias_kind":"pith_short_8","alias_value":"D5YLK67X","created_at":"2026-07-05T04:10:45Z"}],"graph_snapshots":[{"event_id":"sha256:0153f57609686a041c9844d7aaa8ffa95e68abcea67ddbd99e40a220e97a02cb","target":"graph","created_at":"2026-07-05T04:10:45Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2204.00290/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Clinical trials offer a fundamental opportunity to discover new treatments and advance the medical knowledge. However, the uncertainty of the outcome of a trial can lead to unforeseen costs and setbacks. In this study, we propose a new method to predict the effectiveness of an intervention in a clinical trial. Our method relies on generating an informative summary from multiple documents available in the literature about the intervention under study. Specifically, our method first gathers all the abstracts of PubMed articles related to the intervention. Then, an evidence sentence, which convey","authors_text":"Georgios Katsimpras, Georgios Paliouras","cross_cats":["cs.LG"],"headline":"","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CL","submitted_at":"2022-04-01T08:45:39Z","title":"Predicting Intervention Approval in Clinical Trials through Multi-Document Summarization"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2204.00290","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:3a7fc0e0c3a0fa42ccea3a827251aedcce8f4420ffbb82b5736e9ea2c8af1b87","target":"record","created_at":"2026-07-05T04:10:45Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"6add63cd30c2ee15a8b77df5fe4c2efb8c7dabcfae3df7608347978111fdceac","cross_cats_sorted":["cs.LG"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"cs.CL","submitted_at":"2022-04-01T08:45:39Z","title_canon_sha256":"08802bebfeb280cf6103089821de830f60887e21d2a65ce67b9cd83f65edd201"},"schema_version":"1.0","source":{"id":"2204.00290","kind":"arxiv","version":1}},"canonical_sha256":"1f70b57bf7c4de0f72355905614e5f6892c90ab4ccffffc0f42c942e56127861","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"1f70b57bf7c4de0f72355905614e5f6892c90ab4ccffffc0f42c942e56127861","first_computed_at":"2026-07-05T04:10:45.368182Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T04:10:45.368182Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"cJPeDsS8djcP5NXeGwrR+pPZOY5T+s7l9dmC9kM1RI6exEuhBXjGd6UUwDre876aC6I0CiHsrpBQfeOG6GUeDQ==","signature_status":"signed_v1","signed_at":"2026-07-05T04:10:45.368538Z","signed_message":"canonical_sha256_bytes"},"source_id":"2204.00290","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:3a7fc0e0c3a0fa42ccea3a827251aedcce8f4420ffbb82b5736e9ea2c8af1b87","sha256:0153f57609686a041c9844d7aaa8ffa95e68abcea67ddbd99e40a220e97a02cb"],"state_sha256":"234c2fa73e948a1b3443584faa3bc8bece8a0d0656ef1429fd1c922c7639d123"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"5cKZBTfbsMIXC6wgc0BV2cmmBXbXZi0ZcA0b5/zJGadCCReNfQT7Q4vHZmzwRydDjvvcUUfXsR0TW+Z58+DbAw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-16T15:42:12.744362Z","bundle_sha256":"739ee1bd98f78a69e6562b0660985c8d6fd133a9e42b7c8391426679a0d7702c"}}