{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2021:DFKPKAD2WS3LL7EGOWSIJYKH5U","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"cbecb4c7651e40bf67c1ce25100337000e35e83f5bf9e5fb49fc7ef67c82a3c6","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-07-29T11:44:13Z","title_canon_sha256":"22152183a6596ad332a06556224451ed7414c8d87d3878f9c103b2dffcb1413f"},"schema_version":"1.0","source":{"id":"2107.13913","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2107.13913","created_at":"2026-07-05T03:02:18Z"},{"alias_kind":"arxiv_version","alias_value":"2107.13913v2","created_at":"2026-07-05T03:02:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2107.13913","created_at":"2026-07-05T03:02:18Z"},{"alias_kind":"pith_short_12","alias_value":"DFKPKAD2WS3L","created_at":"2026-07-05T03:02:18Z"},{"alias_kind":"pith_short_16","alias_value":"DFKPKAD2WS3LL7EG","created_at":"2026-07-05T03:02:18Z"},{"alias_kind":"pith_short_8","alias_value":"DFKPKAD2","created_at":"2026-07-05T03:02:18Z"}],"graph_snapshots":[{"event_id":"sha256:7d836332a26ced3a6bfccc5af7b0dd033aca99606684f939acef6864e6dce247","target":"graph","created_at":"2026-07-05T03:02:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2107.13913/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"We highlight emerging uses of artificial intelligence (AI) in the field of theranostics, focusing on its significant potential to enable routine and reliable personalization of radiopharmaceutical therapies (RPTs). Personalized RPTs require patient-individual dosimetry calculations accompanying therapy. Image-based dosimetry needs: 1) quantitative imaging; 2) co-registration and organ/tumor identification on serial and multimodality images; 3) determination of the time-integrated activity; and 4) absorbed dose determination. AI models that facilitate these steps are reviewed. Additionally we d","authors_text":"Arman Rahmim, Babak Saboury, Carlos Uribe, Fereshteh Yousefirizi, Jean-Mathieu Beauregard, Julia Brosch-Lenz, Katherine Zukotynski, Vincent Gaudet","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-07-29T11:44:13Z","title":"Role of AI in Theranostics: Towards Routine Personalized Radiopharmaceutical Therapies"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2107.13913","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:eafa6e4102385cc6a1688a93f4251bf82568f9f94291f127610b7e494d47c3aa","target":"record","created_at":"2026-07-05T03:02:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"cbecb4c7651e40bf67c1ce25100337000e35e83f5bf9e5fb49fc7ef67c82a3c6","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"physics.med-ph","submitted_at":"2021-07-29T11:44:13Z","title_canon_sha256":"22152183a6596ad332a06556224451ed7414c8d87d3878f9c103b2dffcb1413f"},"schema_version":"1.0","source":{"id":"2107.13913","kind":"arxiv","version":2}},"canonical_sha256":"1954f5007ab4b6b5fc8675a484e147ed13c87728cf1872cf7b639af917d69d8f","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"1954f5007ab4b6b5fc8675a484e147ed13c87728cf1872cf7b639af917d69d8f","first_computed_at":"2026-07-05T03:02:18.153289Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T03:02:18.153289Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"J9Ywm22n4rsHYsFIC/4HTuNFjPgYR/l+lcGFZTUe+mEBndzg7QDxx4Jsd7Re90Omiz+3DjXgOEhbpM7Ea2eVDA==","signature_status":"signed_v1","signed_at":"2026-07-05T03:02:18.153747Z","signed_message":"canonical_sha256_bytes"},"source_id":"2107.13913","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:eafa6e4102385cc6a1688a93f4251bf82568f9f94291f127610b7e494d47c3aa","sha256:7d836332a26ced3a6bfccc5af7b0dd033aca99606684f939acef6864e6dce247"],"state_sha256":"29ee5d915b595e8f0a6c644fe1066230755a31dbc8c647919e1f9cb4899ba369"}