{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2012:DZWLMLNFQZRSYPBJWWYUN2FGNH","short_pith_number":"pith:DZWLMLNF","canonical_record":{"source":{"id":"1207.0280","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.AP","submitted_at":"2012-07-02T05:24:50Z","cross_cats_sorted":[],"title_canon_sha256":"3b2cc8a8b34a32067e030595efb6a061fa71f6d453cca52984c0301074253e96","abstract_canon_sha256":"5caaa31a8734d258f123613b96392e4c5bc059285350e47dbd9fa7ab9f4a3bb7"},"schema_version":"1.0"},"canonical_sha256":"1e6cb62da586632c3c29b5b146e8a669d4701a0aa286bcf3849d9d5b4d611af7","source":{"kind":"arxiv","id":"1207.0280","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1207.0280","created_at":"2026-05-18T03:51:57Z"},{"alias_kind":"arxiv_version","alias_value":"1207.0280v2","created_at":"2026-05-18T03:51:57Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1207.0280","created_at":"2026-05-18T03:51:57Z"},{"alias_kind":"pith_short_12","alias_value":"DZWLMLNFQZRS","created_at":"2026-05-18T12:27:04Z"},{"alias_kind":"pith_short_16","alias_value":"DZWLMLNFQZRSYPBJ","created_at":"2026-05-18T12:27:04Z"},{"alias_kind":"pith_short_8","alias_value":"DZWLMLNF","created_at":"2026-05-18T12:27:04Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2012:DZWLMLNFQZRSYPBJWWYUN2FGNH","target":"record","payload":{"canonical_record":{"source":{"id":"1207.0280","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.AP","submitted_at":"2012-07-02T05:24:50Z","cross_cats_sorted":[],"title_canon_sha256":"3b2cc8a8b34a32067e030595efb6a061fa71f6d453cca52984c0301074253e96","abstract_canon_sha256":"5caaa31a8734d258f123613b96392e4c5bc059285350e47dbd9fa7ab9f4a3bb7"},"schema_version":"1.0"},"canonical_sha256":"1e6cb62da586632c3c29b5b146e8a669d4701a0aa286bcf3849d9d5b4d611af7","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T03:51:57.907040Z","signature_b64":"CV48OTuCi2N64AScwmdh6hOTDIc33cc7UJLcorPqXKt0EiH2JYA0u3BdrJItyh7C7+7woTptDw3Wcfy3SHHHBg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"1e6cb62da586632c3c29b5b146e8a669d4701a0aa286bcf3849d9d5b4d611af7","last_reissued_at":"2026-05-18T03:51:57.906413Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T03:51:57.906413Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1207.0280","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:51:57Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"uCyVA+9fXVHjxQtPONGhy0O+s2Ri8jXmCHATSq7gdPtahPyAGQ8Pp9VCmS326MSIaoG6MfYxuBM0062npJZfDA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-28T09:05:52.499287Z"},"content_sha256":"8403b520de6510eaef8027a92983324515b6e897ee44054fe66cd53ab773fb7a","schema_version":"1.0","event_id":"sha256:8403b520de6510eaef8027a92983324515b6e897ee44054fe66cd53ab773fb7a"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2012:DZWLMLNFQZRSYPBJWWYUN2FGNH","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Simultaneous SNP identification in association studies with missing data","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"stat.AP","authors_text":"George Casella, John M. Davis, Vikneswaran Gopal, Xiaobo Li, Zhen Li","submitted_at":"2012-07-02T05:24:50Z","abstract_excerpt":"Association testing aims to discover the underlying relationship between genotypes (usually Single Nucleotide Polymorphisms, or SNPs) and phenotypes (attributes, or traits). The typically large data sets used in association testing often contain missing values. Standard statistical methods either impute the missing values using relatively simple assumptions, or delete them, or both, which can generate biased results. Here we describe the Bayesian hierarchical model BAMD (Bayesian Association with Missing Data). BAMD is a Gibbs sampler, in which missing values are multiply imputed based upon al"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1207.0280","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:51:57Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"a0Kfj/lgAMQF7zVdqWau4mMAWUv/92Xi+pVlj2W0tU/O5xdfAHkceCqbnmhOFXshbpd0qdgn2Uhvm/iqpLecCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-28T09:05:52.499655Z"},"content_sha256":"a12f666ffba254ee620701dc3833c2daa286f0c5da8e575b713269125e65dcb2","schema_version":"1.0","event_id":"sha256:a12f666ffba254ee620701dc3833c2daa286f0c5da8e575b713269125e65dcb2"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/DZWLMLNFQZRSYPBJWWYUN2FGNH/bundle.json","state_url":"https://pith.science/pith/DZWLMLNFQZRSYPBJWWYUN2FGNH/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/DZWLMLNFQZRSYPBJWWYUN2FGNH/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-28T09:05:52Z","links":{"resolver":"https://pith.science/pith/DZWLMLNFQZRSYPBJWWYUN2FGNH","bundle":"https://pith.science/pith/DZWLMLNFQZRSYPBJWWYUN2FGNH/bundle.json","state":"https://pith.science/pith/DZWLMLNFQZRSYPBJWWYUN2FGNH/state.json","well_known_bundle":"https://pith.science/.well-known/pith/DZWLMLNFQZRSYPBJWWYUN2FGNH/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2012:DZWLMLNFQZRSYPBJWWYUN2FGNH","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"5caaa31a8734d258f123613b96392e4c5bc059285350e47dbd9fa7ab9f4a3bb7","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.AP","submitted_at":"2012-07-02T05:24:50Z","title_canon_sha256":"3b2cc8a8b34a32067e030595efb6a061fa71f6d453cca52984c0301074253e96"},"schema_version":"1.0","source":{"id":"1207.0280","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1207.0280","created_at":"2026-05-18T03:51:57Z"},{"alias_kind":"arxiv_version","alias_value":"1207.0280v2","created_at":"2026-05-18T03:51:57Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1207.0280","created_at":"2026-05-18T03:51:57Z"},{"alias_kind":"pith_short_12","alias_value":"DZWLMLNFQZRS","created_at":"2026-05-18T12:27:04Z"},{"alias_kind":"pith_short_16","alias_value":"DZWLMLNFQZRSYPBJ","created_at":"2026-05-18T12:27:04Z"},{"alias_kind":"pith_short_8","alias_value":"DZWLMLNF","created_at":"2026-05-18T12:27:04Z"}],"graph_snapshots":[{"event_id":"sha256:a12f666ffba254ee620701dc3833c2daa286f0c5da8e575b713269125e65dcb2","target":"graph","created_at":"2026-05-18T03:51:57Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Association testing aims to discover the underlying relationship between genotypes (usually Single Nucleotide Polymorphisms, or SNPs) and phenotypes (attributes, or traits). The typically large data sets used in association testing often contain missing values. Standard statistical methods either impute the missing values using relatively simple assumptions, or delete them, or both, which can generate biased results. Here we describe the Bayesian hierarchical model BAMD (Bayesian Association with Missing Data). BAMD is a Gibbs sampler, in which missing values are multiply imputed based upon al","authors_text":"George Casella, John M. Davis, Vikneswaran Gopal, Xiaobo Li, Zhen Li","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.AP","submitted_at":"2012-07-02T05:24:50Z","title":"Simultaneous SNP identification in association studies with missing data"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1207.0280","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:8403b520de6510eaef8027a92983324515b6e897ee44054fe66cd53ab773fb7a","target":"record","created_at":"2026-05-18T03:51:57Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"5caaa31a8734d258f123613b96392e4c5bc059285350e47dbd9fa7ab9f4a3bb7","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.AP","submitted_at":"2012-07-02T05:24:50Z","title_canon_sha256":"3b2cc8a8b34a32067e030595efb6a061fa71f6d453cca52984c0301074253e96"},"schema_version":"1.0","source":{"id":"1207.0280","kind":"arxiv","version":2}},"canonical_sha256":"1e6cb62da586632c3c29b5b146e8a669d4701a0aa286bcf3849d9d5b4d611af7","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"1e6cb62da586632c3c29b5b146e8a669d4701a0aa286bcf3849d9d5b4d611af7","first_computed_at":"2026-05-18T03:51:57.906413Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T03:51:57.906413Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"CV48OTuCi2N64AScwmdh6hOTDIc33cc7UJLcorPqXKt0EiH2JYA0u3BdrJItyh7C7+7woTptDw3Wcfy3SHHHBg==","signature_status":"signed_v1","signed_at":"2026-05-18T03:51:57.907040Z","signed_message":"canonical_sha256_bytes"},"source_id":"1207.0280","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:8403b520de6510eaef8027a92983324515b6e897ee44054fe66cd53ab773fb7a","sha256:a12f666ffba254ee620701dc3833c2daa286f0c5da8e575b713269125e65dcb2"],"state_sha256":"b8407dba2e95db8e9ef6353ce56e39cd428b57ff803d8dd4e2cf740c15b364f2"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"vqqVrulnxjLHc5x6dZ2V9sUKl8rCThxHGcG3ATfPz+kiVlmmv4JoEGCs5rDLIlTxH/dEcBRaDRJHfxcqObv7AQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-28T09:05:52.501759Z","bundle_sha256":"4996a15e7fb0104fdd1707fa0bfbf5718269c252bf9cd682d38abc0ceae85e2c"}}