{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2014:E53HQQQS3BEGEYRNGH5AAPQOSM","short_pith_number":"pith:E53HQQQS","schema_version":"1.0","canonical_sha256":"2776784212d84862622d31fa003e0e93378fae4cf6d264b14662c6e3f9c7209f","source":{"kind":"arxiv","id":"1405.4538","version":3},"attestation_state":"computed","paper":{"title":"Unit-free and robust detection of differential expression from RNA-Seq data","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"stat.ME","authors_text":"Hui Jiang, Tianyu Zhan","submitted_at":"2014-05-18T19:09:10Z","abstract_excerpt":"Ultra high-throughput sequencing of transcriptomes (RNA-Seq) is a widely used method for quantifying gene expression levels due to its low cost, high accuracy and wide dynamic range for detection. However, the nature of RNA-Seq makes it nearly impossible to provide absolute measurements of transcript abundances. Several units or data summarization methods for transcript quantification have been proposed in the past to account for differences in transcript lengths and sequencing depths across different genes and different samples. Nevertheless, further between-sample normalization is still need"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1405.4538","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ME","submitted_at":"2014-05-18T19:09:10Z","cross_cats_sorted":[],"title_canon_sha256":"655997330eaf5e1b41c4472f0465ce86a4a5c08e0feaa72129759415cbbe4f26","abstract_canon_sha256":"7a2c81095a41544cdf2102d5c63ea4de05c419838e4c50a97f458c6815e4951d"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:07:52.624264Z","signature_b64":"V7dn/R7N6fnRA+PCfrSTRXvhrCxGagqElIeNLDCyQzY7EPqFyfEGdbfK1MQ+xKz5AMRA53w5rLGXwCavSSbGDw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"2776784212d84862622d31fa003e0e93378fae4cf6d264b14662c6e3f9c7209f","last_reissued_at":"2026-05-18T01:07:52.623843Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:07:52.623843Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Unit-free and robust detection of differential expression from RNA-Seq data","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"stat.ME","authors_text":"Hui Jiang, Tianyu Zhan","submitted_at":"2014-05-18T19:09:10Z","abstract_excerpt":"Ultra high-throughput sequencing of transcriptomes (RNA-Seq) is a widely used method for quantifying gene expression levels due to its low cost, high accuracy and wide dynamic range for detection. However, the nature of RNA-Seq makes it nearly impossible to provide absolute measurements of transcript abundances. Several units or data summarization methods for transcript quantification have been proposed in the past to account for differences in transcript lengths and sequencing depths across different genes and different samples. Nevertheless, further between-sample normalization is still need"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1405.4538","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1405.4538","created_at":"2026-05-18T01:07:52.623905+00:00"},{"alias_kind":"arxiv_version","alias_value":"1405.4538v3","created_at":"2026-05-18T01:07:52.623905+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1405.4538","created_at":"2026-05-18T01:07:52.623905+00:00"},{"alias_kind":"pith_short_12","alias_value":"E53HQQQS3BEG","created_at":"2026-05-18T12:28:25.294606+00:00"},{"alias_kind":"pith_short_16","alias_value":"E53HQQQS3BEGEYRN","created_at":"2026-05-18T12:28:25.294606+00:00"},{"alias_kind":"pith_short_8","alias_value":"E53HQQQS","created_at":"2026-05-18T12:28:25.294606+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/E53HQQQS3BEGEYRNGH5AAPQOSM","json":"https://pith.science/pith/E53HQQQS3BEGEYRNGH5AAPQOSM.json","graph_json":"https://pith.science/api/pith-number/E53HQQQS3BEGEYRNGH5AAPQOSM/graph.json","events_json":"https://pith.science/api/pith-number/E53HQQQS3BEGEYRNGH5AAPQOSM/events.json","paper":"https://pith.science/paper/E53HQQQS"},"agent_actions":{"view_html":"https://pith.science/pith/E53HQQQS3BEGEYRNGH5AAPQOSM","download_json":"https://pith.science/pith/E53HQQQS3BEGEYRNGH5AAPQOSM.json","view_paper":"https://pith.science/paper/E53HQQQS","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1405.4538&json=true","fetch_graph":"https://pith.science/api/pith-number/E53HQQQS3BEGEYRNGH5AAPQOSM/graph.json","fetch_events":"https://pith.science/api/pith-number/E53HQQQS3BEGEYRNGH5AAPQOSM/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/E53HQQQS3BEGEYRNGH5AAPQOSM/action/timestamp_anchor","attest_storage":"https://pith.science/pith/E53HQQQS3BEGEYRNGH5AAPQOSM/action/storage_attestation","attest_author":"https://pith.science/pith/E53HQQQS3BEGEYRNGH5AAPQOSM/action/author_attestation","sign_citation":"https://pith.science/pith/E53HQQQS3BEGEYRNGH5AAPQOSM/action/citation_signature","submit_replication":"https://pith.science/pith/E53HQQQS3BEGEYRNGH5AAPQOSM/action/replication_record"}},"created_at":"2026-05-18T01:07:52.623905+00:00","updated_at":"2026-05-18T01:07:52.623905+00:00"}