{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2009:EJTGN4V5IMI7I2IGZABCIVV7CB","short_pith_number":"pith:EJTGN4V5","canonical_record":{"source":{"id":"0906.5173","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2009-06-28T22:17:44Z","cross_cats_sorted":[],"title_canon_sha256":"6d9c16457abd33e46dedf636805674bb5f20a82f7e9c20f61b79f696e2129951","abstract_canon_sha256":"a441e6ca1b9e7bf4e55ba603c9ccb7684fea8ee1f4070c67ef4a6ddd8ad0fd47"},"schema_version":"1.0"},"canonical_sha256":"226666f2bd4311f46906c8022456bf1065fa1d2d62f75fb0a784ae44be3094d8","source":{"kind":"arxiv","id":"0906.5173","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"0906.5173","created_at":"2026-05-18T02:13:12Z"},{"alias_kind":"arxiv_version","alias_value":"0906.5173v1","created_at":"2026-05-18T02:13:12Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.0906.5173","created_at":"2026-05-18T02:13:12Z"},{"alias_kind":"pith_short_12","alias_value":"EJTGN4V5IMI7","created_at":"2026-05-18T12:25:59Z"},{"alias_kind":"pith_short_16","alias_value":"EJTGN4V5IMI7I2IG","created_at":"2026-05-18T12:25:59Z"},{"alias_kind":"pith_short_8","alias_value":"EJTGN4V5","created_at":"2026-05-18T12:25:59Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2009:EJTGN4V5IMI7I2IGZABCIVV7CB","target":"record","payload":{"canonical_record":{"source":{"id":"0906.5173","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2009-06-28T22:17:44Z","cross_cats_sorted":[],"title_canon_sha256":"6d9c16457abd33e46dedf636805674bb5f20a82f7e9c20f61b79f696e2129951","abstract_canon_sha256":"a441e6ca1b9e7bf4e55ba603c9ccb7684fea8ee1f4070c67ef4a6ddd8ad0fd47"},"schema_version":"1.0"},"canonical_sha256":"226666f2bd4311f46906c8022456bf1065fa1d2d62f75fb0a784ae44be3094d8","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T02:13:12.140245Z","signature_b64":"1eEzL5tqFJeiplTz+zyYpp1a/6Qf9MNz39bt3l8B5FfA9tnZGePzls+z5iHkHBal3pWFawmgUAGT2DJWNjhiAw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"226666f2bd4311f46906c8022456bf1065fa1d2d62f75fb0a784ae44be3094d8","last_reissued_at":"2026-05-18T02:13:12.139671Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T02:13:12.139671Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"0906.5173","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:13:12Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Stjm8CrkhASvZ1SGNuXK5LoLdVpXMrl3Reu4pGaboMlkh2liR49EWbzqm9aCBdCLltqTWKe1aFoGe7Y74Y0ZAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T10:26:41.730369Z"},"content_sha256":"e0242ebf61d697d015e31a57dce6f44ae2eaae3bdb6fe917a43eb4a7d01ec76b","schema_version":"1.0","event_id":"sha256:e0242ebf61d697d015e31a57dce6f44ae2eaae3bdb6fe917a43eb4a7d01ec76b"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2009:EJTGN4V5IMI7I2IGZABCIVV7CB","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Self-organized Models of Selectivity in Ca and Na Channels","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.SC","authors_text":"Bob Eisenberg","submitted_at":"2009-06-28T22:17:44Z","abstract_excerpt":"A simple pillbox model with two adjustable parameters accounts for the selectivity of both DEEA Ca channels and DEKA Na channels in many ionic solutions of different composition and concentration. Only the side chains are different in the model of the Ca and Na channels. Parameters are the same for both channels in all solutions. 'Pauling' radii are used for ions. No information from crystal structures is used in the model. Side chains are grossly approximated as spheres. The predicted properties of the Na and Ca channels are very different. How can such a simple model give such powerful resul"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"0906.5173","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:13:12Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"t7rvCbwgT3Oml91TBvUVALgR1jcQM1EtVlyrncpRgVmRyzbVR9K0PUi5B+X5hbNMNhTG8hDLNWWUi/vAEhGOBw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T10:26:41.730758Z"},"content_sha256":"fb3473e8d5582ad2a6752a940342a87a48e240646633caa4f220d8635850ef4b","schema_version":"1.0","event_id":"sha256:fb3473e8d5582ad2a6752a940342a87a48e240646633caa4f220d8635850ef4b"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/EJTGN4V5IMI7I2IGZABCIVV7CB/bundle.json","state_url":"https://pith.science/pith/EJTGN4V5IMI7I2IGZABCIVV7CB/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/EJTGN4V5IMI7I2IGZABCIVV7CB/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T10:26:41Z","links":{"resolver":"https://pith.science/pith/EJTGN4V5IMI7I2IGZABCIVV7CB","bundle":"https://pith.science/pith/EJTGN4V5IMI7I2IGZABCIVV7CB/bundle.json","state":"https://pith.science/pith/EJTGN4V5IMI7I2IGZABCIVV7CB/state.json","well_known_bundle":"https://pith.science/.well-known/pith/EJTGN4V5IMI7I2IGZABCIVV7CB/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2009:EJTGN4V5IMI7I2IGZABCIVV7CB","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"a441e6ca1b9e7bf4e55ba603c9ccb7684fea8ee1f4070c67ef4a6ddd8ad0fd47","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2009-06-28T22:17:44Z","title_canon_sha256":"6d9c16457abd33e46dedf636805674bb5f20a82f7e9c20f61b79f696e2129951"},"schema_version":"1.0","source":{"id":"0906.5173","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"0906.5173","created_at":"2026-05-18T02:13:12Z"},{"alias_kind":"arxiv_version","alias_value":"0906.5173v1","created_at":"2026-05-18T02:13:12Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.0906.5173","created_at":"2026-05-18T02:13:12Z"},{"alias_kind":"pith_short_12","alias_value":"EJTGN4V5IMI7","created_at":"2026-05-18T12:25:59Z"},{"alias_kind":"pith_short_16","alias_value":"EJTGN4V5IMI7I2IG","created_at":"2026-05-18T12:25:59Z"},{"alias_kind":"pith_short_8","alias_value":"EJTGN4V5","created_at":"2026-05-18T12:25:59Z"}],"graph_snapshots":[{"event_id":"sha256:fb3473e8d5582ad2a6752a940342a87a48e240646633caa4f220d8635850ef4b","target":"graph","created_at":"2026-05-18T02:13:12Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"A simple pillbox model with two adjustable parameters accounts for the selectivity of both DEEA Ca channels and DEKA Na channels in many ionic solutions of different composition and concentration. Only the side chains are different in the model of the Ca and Na channels. Parameters are the same for both channels in all solutions. 'Pauling' radii are used for ions. No information from crystal structures is used in the model. Side chains are grossly approximated as spheres. The predicted properties of the Na and Ca channels are very different. How can such a simple model give such powerful resul","authors_text":"Bob Eisenberg","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2009-06-28T22:17:44Z","title":"Self-organized Models of Selectivity in Ca and Na Channels"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"0906.5173","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:e0242ebf61d697d015e31a57dce6f44ae2eaae3bdb6fe917a43eb4a7d01ec76b","target":"record","created_at":"2026-05-18T02:13:12Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"a441e6ca1b9e7bf4e55ba603c9ccb7684fea8ee1f4070c67ef4a6ddd8ad0fd47","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2009-06-28T22:17:44Z","title_canon_sha256":"6d9c16457abd33e46dedf636805674bb5f20a82f7e9c20f61b79f696e2129951"},"schema_version":"1.0","source":{"id":"0906.5173","kind":"arxiv","version":1}},"canonical_sha256":"226666f2bd4311f46906c8022456bf1065fa1d2d62f75fb0a784ae44be3094d8","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"226666f2bd4311f46906c8022456bf1065fa1d2d62f75fb0a784ae44be3094d8","first_computed_at":"2026-05-18T02:13:12.139671Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T02:13:12.139671Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"1eEzL5tqFJeiplTz+zyYpp1a/6Qf9MNz39bt3l8B5FfA9tnZGePzls+z5iHkHBal3pWFawmgUAGT2DJWNjhiAw==","signature_status":"signed_v1","signed_at":"2026-05-18T02:13:12.140245Z","signed_message":"canonical_sha256_bytes"},"source_id":"0906.5173","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:e0242ebf61d697d015e31a57dce6f44ae2eaae3bdb6fe917a43eb4a7d01ec76b","sha256:fb3473e8d5582ad2a6752a940342a87a48e240646633caa4f220d8635850ef4b"],"state_sha256":"241f8f2ca44994dd10533dabcc3096a8a6993d152bbd7a2c329cc86418b3778e"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"hNBmeNEsHIj8OCBSwxK/G5/BXkW306uNN9iaV4hiWudodzUMXAKBqza6tJx12LqRZAaxnVUUzJSknzCUPh7RCw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T10:26:41.733282Z","bundle_sha256":"4c7567e7dbb4c093f80975de00d7ee775c35c109365eac708264891600c60f37"}}