{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2026:FDNJEHAL47LXOOSPHUFX7KAXOR","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"1cdaa3feab126df2830ab49f569d64c4b2cda23f7d737694000c36e1d5a6e45a","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.QM","submitted_at":"2026-07-07T10:38:41Z","title_canon_sha256":"01ae197688575111dd060c545d2e66aa121b14907062941c6ed54e564cb3d850"},"schema_version":"1.0","source":{"id":"2607.06129","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2607.06129","created_at":"2026-07-08T01:18:57Z"},{"alias_kind":"arxiv_version","alias_value":"2607.06129v1","created_at":"2026-07-08T01:18:57Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2607.06129","created_at":"2026-07-08T01:18:57Z"},{"alias_kind":"pith_short_12","alias_value":"FDNJEHAL47LX","created_at":"2026-07-08T01:18:57Z"},{"alias_kind":"pith_short_16","alias_value":"FDNJEHAL47LXOOSP","created_at":"2026-07-08T01:18:57Z"},{"alias_kind":"pith_short_8","alias_value":"FDNJEHAL","created_at":"2026-07-08T01:18:57Z"}],"graph_snapshots":[{"event_id":"sha256:d261f291d595e1296560a82ed0a61422601e33bd63e799976433eb37d7299107","target":"graph","created_at":"2026-07-08T01:18:57Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2607.06129/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Diffuse large B-cell lymphoma (DLBCL) is an aggressive form of non-Hodgkin lymphoma with a high recurrence rate. The molecular profiling of DLBCL tumors culminated in several immunohistochemistry algorithms for prognostic stratification. Among those, the Hans classifier is widely used for classifying DLBCL into germinal center B-cell-like (GCB) and non-germinal center/activated B-cell-like (non-GCB/ABC) subtypes. The Hans classifier primarily evaluates protein expression of tumor-associated markers, however the tumor microenvironment (TME) of DLBCL includes a myriad of immune and stromal cells","authors_text":"Adrian Georg Simon, Alexandra Just, Christian Kukat, Katarzyna Bozek, Marcel Kirchner, Marta Pistone, Martim Dias Gomes, No\\'emie Moreau, Reinhardt Buettner, Stefano Ugliano","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.QM","submitted_at":"2026-07-07T10:38:41Z","title":"Characterization of DLBCL cell of origin-phenotypes based on tumor microenvironment features"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2607.06129","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:212317dbc1b09330e37a220ed3b727db3c4948ba5cdba9d9abcc47ba49d729c4","target":"record","created_at":"2026-07-08T01:18:57Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"1cdaa3feab126df2830ab49f569d64c4b2cda23f7d737694000c36e1d5a6e45a","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.QM","submitted_at":"2026-07-07T10:38:41Z","title_canon_sha256":"01ae197688575111dd060c545d2e66aa121b14907062941c6ed54e564cb3d850"},"schema_version":"1.0","source":{"id":"2607.06129","kind":"arxiv","version":1}},"canonical_sha256":"28da921c0be7d7773a4f3d0b7fa8177474a54c2815ef56086793cdfd787770d0","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"28da921c0be7d7773a4f3d0b7fa8177474a54c2815ef56086793cdfd787770d0","first_computed_at":"2026-07-08T01:18:57.901255Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-08T01:18:57.901255Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"tEIFKv8WFYk4xs0X+Bx1X+sGDbN4Hw4vPE/Ft9Xjl577dl5ZrGaT8CXpGPLfHYJyBlxq/c9znpClH4L+NtomDg==","signature_status":"signed_v1","signed_at":"2026-07-08T01:18:57.901679Z","signed_message":"canonical_sha256_bytes"},"source_id":"2607.06129","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:212317dbc1b09330e37a220ed3b727db3c4948ba5cdba9d9abcc47ba49d729c4","sha256:d261f291d595e1296560a82ed0a61422601e33bd63e799976433eb37d7299107"],"state_sha256":"97b040afc41cead39f5c9261c2ded949c20f926c9329be278cedb25c1140391d"}