{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2012:FIFKC4QK5YOF2TRBZIDNATZNXR","short_pith_number":"pith:FIFKC4QK","schema_version":"1.0","canonical_sha256":"2a0aa1720aee1c5d4e21ca06d04f2dbc6748615c75814965699781cc5f523d12","source":{"kind":"arxiv","id":"1207.1516","version":1},"attestation_state":"computed","paper":{"title":"Mechanical Instabilities of Biological Tubes","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.TO"],"primary_cat":"physics.bio-ph","authors_text":"Edouard Hannezo, Jacques Prost, Jean-Francois Joanny","submitted_at":"2012-07-06T04:19:53Z","abstract_excerpt":"We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their division provokes a buckling instability. Several shapes are investigated : varicose, enlarged, sinusoidal or sausage-like, all of which are found in pathologies of tracheal, renal tubes or arteries. The final shape depends crucially on the mechanical parameters of the tissues : Young modulus, wall-to-lumen ratio, homeostatic pressure. We argue that since tissues must be in quasistatic mechanical equilibrium, abnormal "},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1207.1516","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2012-07-06T04:19:53Z","cross_cats_sorted":["q-bio.TO"],"title_canon_sha256":"434481de877f435b143c29b4939e5519b4e8a1cba973db4fa7366c00b46b8515","abstract_canon_sha256":"08fdaec44781416b93a6261cc2d1f82f8eb7b06d71bca0e3d64ee71a18a4e9f0"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T03:51:36.976249Z","signature_b64":"+BQrrtrOLBeMFKVvSs9Tt+VMuHRr3U8XOMoJwHJH01gPzpYPy/xf1A6tE6/0+h6n1AklrNbxfG1TbZa1eYk9CA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"2a0aa1720aee1c5d4e21ca06d04f2dbc6748615c75814965699781cc5f523d12","last_reissued_at":"2026-05-18T03:51:36.975795Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T03:51:36.975795Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Mechanical Instabilities of Biological Tubes","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.TO"],"primary_cat":"physics.bio-ph","authors_text":"Edouard Hannezo, Jacques Prost, Jean-Francois Joanny","submitted_at":"2012-07-06T04:19:53Z","abstract_excerpt":"We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their division provokes a buckling instability. Several shapes are investigated : varicose, enlarged, sinusoidal or sausage-like, all of which are found in pathologies of tracheal, renal tubes or arteries. The final shape depends crucially on the mechanical parameters of the tissues : Young modulus, wall-to-lumen ratio, homeostatic pressure. We argue that since tissues must be in quasistatic mechanical equilibrium, abnormal "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1207.1516","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1207.1516","created_at":"2026-05-18T03:51:36.975858+00:00"},{"alias_kind":"arxiv_version","alias_value":"1207.1516v1","created_at":"2026-05-18T03:51:36.975858+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1207.1516","created_at":"2026-05-18T03:51:36.975858+00:00"},{"alias_kind":"pith_short_12","alias_value":"FIFKC4QK5YOF","created_at":"2026-05-18T12:27:06.952714+00:00"},{"alias_kind":"pith_short_16","alias_value":"FIFKC4QK5YOF2TRB","created_at":"2026-05-18T12:27:06.952714+00:00"},{"alias_kind":"pith_short_8","alias_value":"FIFKC4QK","created_at":"2026-05-18T12:27:06.952714+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/FIFKC4QK5YOF2TRBZIDNATZNXR","json":"https://pith.science/pith/FIFKC4QK5YOF2TRBZIDNATZNXR.json","graph_json":"https://pith.science/api/pith-number/FIFKC4QK5YOF2TRBZIDNATZNXR/graph.json","events_json":"https://pith.science/api/pith-number/FIFKC4QK5YOF2TRBZIDNATZNXR/events.json","paper":"https://pith.science/paper/FIFKC4QK"},"agent_actions":{"view_html":"https://pith.science/pith/FIFKC4QK5YOF2TRBZIDNATZNXR","download_json":"https://pith.science/pith/FIFKC4QK5YOF2TRBZIDNATZNXR.json","view_paper":"https://pith.science/paper/FIFKC4QK","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1207.1516&json=true","fetch_graph":"https://pith.science/api/pith-number/FIFKC4QK5YOF2TRBZIDNATZNXR/graph.json","fetch_events":"https://pith.science/api/pith-number/FIFKC4QK5YOF2TRBZIDNATZNXR/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/FIFKC4QK5YOF2TRBZIDNATZNXR/action/timestamp_anchor","attest_storage":"https://pith.science/pith/FIFKC4QK5YOF2TRBZIDNATZNXR/action/storage_attestation","attest_author":"https://pith.science/pith/FIFKC4QK5YOF2TRBZIDNATZNXR/action/author_attestation","sign_citation":"https://pith.science/pith/FIFKC4QK5YOF2TRBZIDNATZNXR/action/citation_signature","submit_replication":"https://pith.science/pith/FIFKC4QK5YOF2TRBZIDNATZNXR/action/replication_record"}},"created_at":"2026-05-18T03:51:36.975858+00:00","updated_at":"2026-05-18T03:51:36.975858+00:00"}