{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2015:FXP4EYPVOPYJUQRXIPHTSIGPX6","short_pith_number":"pith:FXP4EYPV","canonical_record":{"source":{"id":"1504.05641","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2015-04-22T03:21:27Z","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"title_canon_sha256":"5732df1119f8adbf8ec9a6aa85bff42a19b59cf0bb970ebe6dd21abec1592a0a","abstract_canon_sha256":"8bef83aa598b648a87e2b998d524e9043d474ac51977ec6355f6077ec63b8e75"},"schema_version":"1.0"},"canonical_sha256":"2ddfc261f573f09a423743cf3920cfbfb8ab722a573137a3f222e83664758119","source":{"kind":"arxiv","id":"1504.05641","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1504.05641","created_at":"2026-05-18T02:18:13Z"},{"alias_kind":"arxiv_version","alias_value":"1504.05641v1","created_at":"2026-05-18T02:18:13Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1504.05641","created_at":"2026-05-18T02:18:13Z"},{"alias_kind":"pith_short_12","alias_value":"FXP4EYPVOPYJ","created_at":"2026-05-18T12:29:22Z"},{"alias_kind":"pith_short_16","alias_value":"FXP4EYPVOPYJUQRX","created_at":"2026-05-18T12:29:22Z"},{"alias_kind":"pith_short_8","alias_value":"FXP4EYPV","created_at":"2026-05-18T12:29:22Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2015:FXP4EYPVOPYJUQRXIPHTSIGPX6","target":"record","payload":{"canonical_record":{"source":{"id":"1504.05641","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2015-04-22T03:21:27Z","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"title_canon_sha256":"5732df1119f8adbf8ec9a6aa85bff42a19b59cf0bb970ebe6dd21abec1592a0a","abstract_canon_sha256":"8bef83aa598b648a87e2b998d524e9043d474ac51977ec6355f6077ec63b8e75"},"schema_version":"1.0"},"canonical_sha256":"2ddfc261f573f09a423743cf3920cfbfb8ab722a573137a3f222e83664758119","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T02:18:13.089764Z","signature_b64":"ql3TgJcsK4QmOWk+EtBGD+FCqFUi3fmZ+T8IH9pLcahgeEMr0GtR42A8dxirwR6johcUqdaVRXsgtn8wbsTACA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"2ddfc261f573f09a423743cf3920cfbfb8ab722a573137a3f222e83664758119","last_reissued_at":"2026-05-18T02:18:13.089079Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T02:18:13.089079Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1504.05641","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:18:13Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"alcjXdDNjSJG08GfIf1eXQsl4vbTGebkOm2pv2JkazOZw6Ahq5CShS6hLhUPUmGTWZNqTfyE4Tvo6pd/4/8pCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-04T21:39:41.629282Z"},"content_sha256":"a84cfc4145c1c7021a4754871ca6e294e1b9d548f034ff63987f8efc8a4017e8","schema_version":"1.0","event_id":"sha256:a84cfc4145c1c7021a4754871ca6e294e1b9d548f034ff63987f8efc8a4017e8"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2015:FXP4EYPVOPYJUQRXIPHTSIGPX6","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Surface deformation and shear flow in ligand mediated cell adhesion","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.soft","physics.bio-ph"],"primary_cat":"q-bio.CB","authors_text":"Anthony J. Roberts, Sarthok Sircar","submitted_at":"2015-04-22T03:21:27Z","abstract_excerpt":"We present a single, unified, multi-scale model to study the attachment\\detachment dynamics of two deforming, near spherical cells, coated with binding ligands and subject to a slow, homogeneous shear flow in a viscous fluid medium. The binding ligands on the surface of the cells experience attractive and repulsive forces in an ionic medium and exhibit finite resistance to rotation via bond tilting. The macroscale drag forces and couples describing the fluid flow inside the small separation gap between the cells, are calculated using a combination of methods in lubrication theory and previousl"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1504.05641","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:18:13Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"hcm5HEE3szNFXFatS+jd4GuOxiZBgdedVJ7EQsEQiwPHbdPbb5sps/wmoiZTgJ8/w7MV1wd8J26GUejRlR5mAQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-04T21:39:41.629639Z"},"content_sha256":"da965b5ce8125d7be68d2296345e48417600ff3f50bad5357af00b134960e7a0","schema_version":"1.0","event_id":"sha256:da965b5ce8125d7be68d2296345e48417600ff3f50bad5357af00b134960e7a0"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/FXP4EYPVOPYJUQRXIPHTSIGPX6/bundle.json","state_url":"https://pith.science/pith/FXP4EYPVOPYJUQRXIPHTSIGPX6/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/FXP4EYPVOPYJUQRXIPHTSIGPX6/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-04T21:39:41Z","links":{"resolver":"https://pith.science/pith/FXP4EYPVOPYJUQRXIPHTSIGPX6","bundle":"https://pith.science/pith/FXP4EYPVOPYJUQRXIPHTSIGPX6/bundle.json","state":"https://pith.science/pith/FXP4EYPVOPYJUQRXIPHTSIGPX6/state.json","well_known_bundle":"https://pith.science/.well-known/pith/FXP4EYPVOPYJUQRXIPHTSIGPX6/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2015:FXP4EYPVOPYJUQRXIPHTSIGPX6","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"8bef83aa598b648a87e2b998d524e9043d474ac51977ec6355f6077ec63b8e75","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2015-04-22T03:21:27Z","title_canon_sha256":"5732df1119f8adbf8ec9a6aa85bff42a19b59cf0bb970ebe6dd21abec1592a0a"},"schema_version":"1.0","source":{"id":"1504.05641","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1504.05641","created_at":"2026-05-18T02:18:13Z"},{"alias_kind":"arxiv_version","alias_value":"1504.05641v1","created_at":"2026-05-18T02:18:13Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1504.05641","created_at":"2026-05-18T02:18:13Z"},{"alias_kind":"pith_short_12","alias_value":"FXP4EYPVOPYJ","created_at":"2026-05-18T12:29:22Z"},{"alias_kind":"pith_short_16","alias_value":"FXP4EYPVOPYJUQRX","created_at":"2026-05-18T12:29:22Z"},{"alias_kind":"pith_short_8","alias_value":"FXP4EYPV","created_at":"2026-05-18T12:29:22Z"}],"graph_snapshots":[{"event_id":"sha256:da965b5ce8125d7be68d2296345e48417600ff3f50bad5357af00b134960e7a0","target":"graph","created_at":"2026-05-18T02:18:13Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"We present a single, unified, multi-scale model to study the attachment\\detachment dynamics of two deforming, near spherical cells, coated with binding ligands and subject to a slow, homogeneous shear flow in a viscous fluid medium. The binding ligands on the surface of the cells experience attractive and repulsive forces in an ionic medium and exhibit finite resistance to rotation via bond tilting. The macroscale drag forces and couples describing the fluid flow inside the small separation gap between the cells, are calculated using a combination of methods in lubrication theory and previousl","authors_text":"Anthony J. Roberts, Sarthok Sircar","cross_cats":["cond-mat.soft","physics.bio-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2015-04-22T03:21:27Z","title":"Surface deformation and shear flow in ligand mediated cell adhesion"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1504.05641","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:a84cfc4145c1c7021a4754871ca6e294e1b9d548f034ff63987f8efc8a4017e8","target":"record","created_at":"2026-05-18T02:18:13Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"8bef83aa598b648a87e2b998d524e9043d474ac51977ec6355f6077ec63b8e75","cross_cats_sorted":["cond-mat.soft","physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2015-04-22T03:21:27Z","title_canon_sha256":"5732df1119f8adbf8ec9a6aa85bff42a19b59cf0bb970ebe6dd21abec1592a0a"},"schema_version":"1.0","source":{"id":"1504.05641","kind":"arxiv","version":1}},"canonical_sha256":"2ddfc261f573f09a423743cf3920cfbfb8ab722a573137a3f222e83664758119","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"2ddfc261f573f09a423743cf3920cfbfb8ab722a573137a3f222e83664758119","first_computed_at":"2026-05-18T02:18:13.089079Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T02:18:13.089079Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"ql3TgJcsK4QmOWk+EtBGD+FCqFUi3fmZ+T8IH9pLcahgeEMr0GtR42A8dxirwR6johcUqdaVRXsgtn8wbsTACA==","signature_status":"signed_v1","signed_at":"2026-05-18T02:18:13.089764Z","signed_message":"canonical_sha256_bytes"},"source_id":"1504.05641","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:a84cfc4145c1c7021a4754871ca6e294e1b9d548f034ff63987f8efc8a4017e8","sha256:da965b5ce8125d7be68d2296345e48417600ff3f50bad5357af00b134960e7a0"],"state_sha256":"a931dfc07474e65f75a73627609d25c60b16e5f80bacc680188e336ff6547a7f"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"nEZnfIzd3mFdJ9jcuSZxOC096bDiZiUEbItWbblZXaXApAIpXQlhe2uTBnMCsN5GQaEORHm7MGHbUFMrGhA/Bw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-04T21:39:41.631607Z","bundle_sha256":"df690a46ab36514418be2a9f034ba0ac27b60d903d5bcfad25df3db6040c71b6"}}