{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2024:G7TVLOQAYAH7ORNHUPVG5AR5PV","short_pith_number":"pith:G7TVLOQA","canonical_record":{"source":{"id":"2411.19666","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"eess.IV","submitted_at":"2024-11-29T12:39:57Z","cross_cats_sorted":["cs.AI","cs.CV","cs.LG","stat.AP"],"title_canon_sha256":"18bbdc1a04e3d6d8ccd0bc31d564ea2aa41a0f0d717ee52e3af90931a52d8dfc","abstract_canon_sha256":"64de991e4530cb2c8cd6a0d92de20bb81de8102164a79dab9a22ef3dbdbfe2fd"},"schema_version":"1.0"},"canonical_sha256":"37e755ba00c00ff745a7a3ea6e823d7d65e9c7334183e3c833cd394cc6b1c30c","source":{"kind":"arxiv","id":"2411.19666","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2411.19666","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"arxiv_version","alias_value":"2411.19666v1","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2411.19666","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"pith_short_12","alias_value":"G7TVLOQAYAH7","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"pith_short_16","alias_value":"G7TVLOQAYAH7ORNH","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"pith_short_8","alias_value":"G7TVLOQA","created_at":"2026-07-05T09:42:06Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2024:G7TVLOQAYAH7ORNHUPVG5AR5PV","target":"record","payload":{"canonical_record":{"source":{"id":"2411.19666","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"eess.IV","submitted_at":"2024-11-29T12:39:57Z","cross_cats_sorted":["cs.AI","cs.CV","cs.LG","stat.AP"],"title_canon_sha256":"18bbdc1a04e3d6d8ccd0bc31d564ea2aa41a0f0d717ee52e3af90931a52d8dfc","abstract_canon_sha256":"64de991e4530cb2c8cd6a0d92de20bb81de8102164a79dab9a22ef3dbdbfe2fd"},"schema_version":"1.0"},"canonical_sha256":"37e755ba00c00ff745a7a3ea6e823d7d65e9c7334183e3c833cd394cc6b1c30c","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T09:42:06.281121Z","signature_b64":"ciRSfVFFgih/5+GJbQOqZQ15G/Fiv1ksBus35CPLUff0sZ6/pSD59rUgRIva1cjFyEUrQn6+lk7e/5p4Na3wCg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"37e755ba00c00ff745a7a3ea6e823d7d65e9c7334183e3c833cd394cc6b1c30c","last_reissued_at":"2026-07-05T09:42:06.280588Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T09:42:06.280588Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2411.19666","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T09:42:06Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"rCuDjId9QY19FE4GTXkfejf4TgXLYEfB7WOCIHi1kaqbUmXWNTwJNA98+cgGSpykMD0+w9E5oyNkAS/eVbvxCQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-07T11:02:49.674619Z"},"content_sha256":"0a745468c7da074f4120174e709b95c94a5c6dd8045a0bf1f12fbd350b4c04d3","schema_version":"1.0","event_id":"sha256:0a745468c7da074f4120174e709b95c94a5c6dd8045a0bf1f12fbd350b4c04d3"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2024:G7TVLOQAYAH7ORNHUPVG5AR5PV","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Multimodal Whole Slide Foundation Model for Pathology","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","headline":"","cross_cats":["cs.AI","cs.CV","cs.LG","stat.AP"],"primary_cat":"eess.IV","authors_text":"Ahrong Kim, Akihiro Kawabe, Andrew H. Song, Andrew Zhang, Anurag J. Vaidya, Bowen Chen, Chengkuan Chen, Cristina Almagro-Perez, Daisuke Komura, Drew F.K. Williamson, Faisal Mahmood, Georg Gerber, Guillaume Jaume, Long Phi Le, Ming Y. Lu, Muhammad Shaban, Paul Doucet, Richard J. Chen, Sharifa Sahai, Shumpei Ishikawa, Sophia J. Wagner, Tingying Peng, Tong Ding","submitted_at":"2024-11-29T12:39:57Z","abstract_excerpt":"The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transferable feature representations via self-supervised learning (SSL). However, translating these advancements to address complex clinical challenges at the patient and slide level remains constrained by limited clinical data in disease-specific cohorts, especially for rare clinical conditions. We propose TITAN, a multimodal whole slide foundation model pretrained using 335,645 WSIs via visual self-supervised learning and"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2411.19666","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2411.19666/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T09:42:06Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"BFyxPd3N5Slcrg/RCypooNoYt+ULk93ou6a/QrJJXr4rzJfi+lpNvkCXH5b/k9CI+huzxll/ASQW9tEHRNFwCw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-07T11:02:49.674995Z"},"content_sha256":"863bf59888746ce2977a234f538c0fdb7eebe83daf11f863049d93120dc088c7","schema_version":"1.0","event_id":"sha256:863bf59888746ce2977a234f538c0fdb7eebe83daf11f863049d93120dc088c7"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/G7TVLOQAYAH7ORNHUPVG5AR5PV/bundle.json","state_url":"https://pith.science/pith/G7TVLOQAYAH7ORNHUPVG5AR5PV/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/G7TVLOQAYAH7ORNHUPVG5AR5PV/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-07T11:02:49Z","links":{"resolver":"https://pith.science/pith/G7TVLOQAYAH7ORNHUPVG5AR5PV","bundle":"https://pith.science/pith/G7TVLOQAYAH7ORNHUPVG5AR5PV/bundle.json","state":"https://pith.science/pith/G7TVLOQAYAH7ORNHUPVG5AR5PV/state.json","well_known_bundle":"https://pith.science/.well-known/pith/G7TVLOQAYAH7ORNHUPVG5AR5PV/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2024:G7TVLOQAYAH7ORNHUPVG5AR5PV","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"64de991e4530cb2c8cd6a0d92de20bb81de8102164a79dab9a22ef3dbdbfe2fd","cross_cats_sorted":["cs.AI","cs.CV","cs.LG","stat.AP"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"eess.IV","submitted_at":"2024-11-29T12:39:57Z","title_canon_sha256":"18bbdc1a04e3d6d8ccd0bc31d564ea2aa41a0f0d717ee52e3af90931a52d8dfc"},"schema_version":"1.0","source":{"id":"2411.19666","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2411.19666","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"arxiv_version","alias_value":"2411.19666v1","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2411.19666","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"pith_short_12","alias_value":"G7TVLOQAYAH7","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"pith_short_16","alias_value":"G7TVLOQAYAH7ORNH","created_at":"2026-07-05T09:42:06Z"},{"alias_kind":"pith_short_8","alias_value":"G7TVLOQA","created_at":"2026-07-05T09:42:06Z"}],"graph_snapshots":[{"event_id":"sha256:863bf59888746ce2977a234f538c0fdb7eebe83daf11f863049d93120dc088c7","target":"graph","created_at":"2026-07-05T09:42:06Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2411.19666/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transferable feature representations via self-supervised learning (SSL). However, translating these advancements to address complex clinical challenges at the patient and slide level remains constrained by limited clinical data in disease-specific cohorts, especially for rare clinical conditions. We propose TITAN, a multimodal whole slide foundation model pretrained using 335,645 WSIs via visual self-supervised learning and","authors_text":"Ahrong Kim, Akihiro Kawabe, Andrew H. Song, Andrew Zhang, Anurag J. Vaidya, Bowen Chen, Chengkuan Chen, Cristina Almagro-Perez, Daisuke Komura, Drew F.K. Williamson, Faisal Mahmood, Georg Gerber, Guillaume Jaume, Long Phi Le, Ming Y. Lu, Muhammad Shaban, Paul Doucet, Richard J. Chen, Sharifa Sahai, Shumpei Ishikawa, Sophia J. Wagner, Tingying Peng, Tong Ding","cross_cats":["cs.AI","cs.CV","cs.LG","stat.AP"],"headline":"","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"eess.IV","submitted_at":"2024-11-29T12:39:57Z","title":"Multimodal Whole Slide Foundation Model for Pathology"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2411.19666","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:0a745468c7da074f4120174e709b95c94a5c6dd8045a0bf1f12fbd350b4c04d3","target":"record","created_at":"2026-07-05T09:42:06Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"64de991e4530cb2c8cd6a0d92de20bb81de8102164a79dab9a22ef3dbdbfe2fd","cross_cats_sorted":["cs.AI","cs.CV","cs.LG","stat.AP"],"license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","primary_cat":"eess.IV","submitted_at":"2024-11-29T12:39:57Z","title_canon_sha256":"18bbdc1a04e3d6d8ccd0bc31d564ea2aa41a0f0d717ee52e3af90931a52d8dfc"},"schema_version":"1.0","source":{"id":"2411.19666","kind":"arxiv","version":1}},"canonical_sha256":"37e755ba00c00ff745a7a3ea6e823d7d65e9c7334183e3c833cd394cc6b1c30c","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"37e755ba00c00ff745a7a3ea6e823d7d65e9c7334183e3c833cd394cc6b1c30c","first_computed_at":"2026-07-05T09:42:06.280588Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T09:42:06.280588Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"ciRSfVFFgih/5+GJbQOqZQ15G/Fiv1ksBus35CPLUff0sZ6/pSD59rUgRIva1cjFyEUrQn6+lk7e/5p4Na3wCg==","signature_status":"signed_v1","signed_at":"2026-07-05T09:42:06.281121Z","signed_message":"canonical_sha256_bytes"},"source_id":"2411.19666","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:0a745468c7da074f4120174e709b95c94a5c6dd8045a0bf1f12fbd350b4c04d3","sha256:863bf59888746ce2977a234f538c0fdb7eebe83daf11f863049d93120dc088c7"],"state_sha256":"79d3760b7320c493086adcecd35c5cf0c89d334f594636f183dfd8316af3d854"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Zuj/9YdQnbZ02OiWBDOaAa5h3N32tGQs8+j6Msr6nISlK8Fm7HeQUIdgZ8I123caPWsZ5l7+/3MeoVE+sw6SDg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-07T11:02:49.677030Z","bundle_sha256":"92b76367723295be8773d7ac53eec8c4d9ddf6a25b4a27279750e25a32c4eada"}}