{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2014:GORI4MIDG55D53WJCPOWPL2AAG","short_pith_number":"pith:GORI4MID","canonical_record":{"source":{"id":"1404.0372","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2014-04-01T19:57:16Z","cross_cats_sorted":["physics.bio-ph"],"title_canon_sha256":"81ba6cf384d7af99094eeddb23cfb8f298c35423ce6ae2001ff9ad4578939f7b","abstract_canon_sha256":"a9f28bc51e702923ed97021512de38c59f99881affe8438c645263bbce842368"},"schema_version":"1.0"},"canonical_sha256":"33a28e3103377a3eeec913dd67af4001b1c7e80895916cce60ae775f1138e961","source":{"kind":"arxiv","id":"1404.0372","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1404.0372","created_at":"2026-05-18T01:43:43Z"},{"alias_kind":"arxiv_version","alias_value":"1404.0372v1","created_at":"2026-05-18T01:43:43Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1404.0372","created_at":"2026-05-18T01:43:43Z"},{"alias_kind":"pith_short_12","alias_value":"GORI4MIDG55D","created_at":"2026-05-18T12:28:30Z"},{"alias_kind":"pith_short_16","alias_value":"GORI4MIDG55D53WJ","created_at":"2026-05-18T12:28:30Z"},{"alias_kind":"pith_short_8","alias_value":"GORI4MID","created_at":"2026-05-18T12:28:30Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2014:GORI4MIDG55D53WJCPOWPL2AAG","target":"record","payload":{"canonical_record":{"source":{"id":"1404.0372","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2014-04-01T19:57:16Z","cross_cats_sorted":["physics.bio-ph"],"title_canon_sha256":"81ba6cf384d7af99094eeddb23cfb8f298c35423ce6ae2001ff9ad4578939f7b","abstract_canon_sha256":"a9f28bc51e702923ed97021512de38c59f99881affe8438c645263bbce842368"},"schema_version":"1.0"},"canonical_sha256":"33a28e3103377a3eeec913dd67af4001b1c7e80895916cce60ae775f1138e961","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:43:43.248533Z","signature_b64":"mlt0fe4PmwW+Wp9XsiZvSTwOrjPvvswFt7/DGzu2gRxFcL8hZb0SnZkWzfI4OfikxNWwzH7Mz59paEUcaruKCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"33a28e3103377a3eeec913dd67af4001b1c7e80895916cce60ae775f1138e961","last_reissued_at":"2026-05-18T01:43:43.248095Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:43:43.248095Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1404.0372","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:43:43Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"WwbkibJBC4ZtwxfN+9Ug7dlrlaR7pbPkArUB3K9WVqDkOLjnA8jnl0wLbMQcxqH99Wg1HpyME/C6+M5bXc0oCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-02T13:07:34.550407Z"},"content_sha256":"418e57deba9d8f98f811052333491acae7f5d6fc9524762bde73edf9a654ab6a","schema_version":"1.0","event_id":"sha256:418e57deba9d8f98f811052333491acae7f5d6fc9524762bde73edf9a654ab6a"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2014:GORI4MIDG55D53WJCPOWPL2AAG","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"A computational study of stress fiber-focal adhesion dynamics governing cell contractility","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph"],"primary_cat":"q-bio.SC","authors_text":"Clara Valero, Krishna Garikipati, Mirko Maraldi","submitted_at":"2014-04-01T19:57:16Z","abstract_excerpt":"We apply a recently developed model of cytoskeletal force generation to study a cell intrinsic contractility, as well as its response to external loading. The model is based on a non-equilibrium thermodynamic treatment of the mechano-chemistry governing force in the stress fiber-focal adhesion system. Our computational study suggests that the mechanical coupling between the stress fibers and focal adhesions leads to a complex, dynamic, mechano-chemical response. We collect the results in response maps whose regimes are distinguished by the initial geometry of the stress fiber-focal adhesion sy"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1404.0372","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:43:43Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"OiflwA6GTUxEVldhVB5/Tbg1MJ5jSdKAOLPtepS0YYnk4yN8+7jyyzneN8Cp9E1U6mVahJ84z8CCMKRw17epDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-02T13:07:34.550762Z"},"content_sha256":"9dddf7d4f8e6c83a0be8e07f9d35af6e3e954f594273dd7cd133bee6937a7647","schema_version":"1.0","event_id":"sha256:9dddf7d4f8e6c83a0be8e07f9d35af6e3e954f594273dd7cd133bee6937a7647"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/GORI4MIDG55D53WJCPOWPL2AAG/bundle.json","state_url":"https://pith.science/pith/GORI4MIDG55D53WJCPOWPL2AAG/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/GORI4MIDG55D53WJCPOWPL2AAG/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-02T13:07:34Z","links":{"resolver":"https://pith.science/pith/GORI4MIDG55D53WJCPOWPL2AAG","bundle":"https://pith.science/pith/GORI4MIDG55D53WJCPOWPL2AAG/bundle.json","state":"https://pith.science/pith/GORI4MIDG55D53WJCPOWPL2AAG/state.json","well_known_bundle":"https://pith.science/.well-known/pith/GORI4MIDG55D53WJCPOWPL2AAG/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2014:GORI4MIDG55D53WJCPOWPL2AAG","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"a9f28bc51e702923ed97021512de38c59f99881affe8438c645263bbce842368","cross_cats_sorted":["physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2014-04-01T19:57:16Z","title_canon_sha256":"81ba6cf384d7af99094eeddb23cfb8f298c35423ce6ae2001ff9ad4578939f7b"},"schema_version":"1.0","source":{"id":"1404.0372","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1404.0372","created_at":"2026-05-18T01:43:43Z"},{"alias_kind":"arxiv_version","alias_value":"1404.0372v1","created_at":"2026-05-18T01:43:43Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1404.0372","created_at":"2026-05-18T01:43:43Z"},{"alias_kind":"pith_short_12","alias_value":"GORI4MIDG55D","created_at":"2026-05-18T12:28:30Z"},{"alias_kind":"pith_short_16","alias_value":"GORI4MIDG55D53WJ","created_at":"2026-05-18T12:28:30Z"},{"alias_kind":"pith_short_8","alias_value":"GORI4MID","created_at":"2026-05-18T12:28:30Z"}],"graph_snapshots":[{"event_id":"sha256:9dddf7d4f8e6c83a0be8e07f9d35af6e3e954f594273dd7cd133bee6937a7647","target":"graph","created_at":"2026-05-18T01:43:43Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"We apply a recently developed model of cytoskeletal force generation to study a cell intrinsic contractility, as well as its response to external loading. The model is based on a non-equilibrium thermodynamic treatment of the mechano-chemistry governing force in the stress fiber-focal adhesion system. Our computational study suggests that the mechanical coupling between the stress fibers and focal adhesions leads to a complex, dynamic, mechano-chemical response. We collect the results in response maps whose regimes are distinguished by the initial geometry of the stress fiber-focal adhesion sy","authors_text":"Clara Valero, Krishna Garikipati, Mirko Maraldi","cross_cats":["physics.bio-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2014-04-01T19:57:16Z","title":"A computational study of stress fiber-focal adhesion dynamics governing cell contractility"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1404.0372","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:418e57deba9d8f98f811052333491acae7f5d6fc9524762bde73edf9a654ab6a","target":"record","created_at":"2026-05-18T01:43:43Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"a9f28bc51e702923ed97021512de38c59f99881affe8438c645263bbce842368","cross_cats_sorted":["physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.SC","submitted_at":"2014-04-01T19:57:16Z","title_canon_sha256":"81ba6cf384d7af99094eeddb23cfb8f298c35423ce6ae2001ff9ad4578939f7b"},"schema_version":"1.0","source":{"id":"1404.0372","kind":"arxiv","version":1}},"canonical_sha256":"33a28e3103377a3eeec913dd67af4001b1c7e80895916cce60ae775f1138e961","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"33a28e3103377a3eeec913dd67af4001b1c7e80895916cce60ae775f1138e961","first_computed_at":"2026-05-18T01:43:43.248095Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:43:43.248095Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"mlt0fe4PmwW+Wp9XsiZvSTwOrjPvvswFt7/DGzu2gRxFcL8hZb0SnZkWzfI4OfikxNWwzH7Mz59paEUcaruKCA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:43:43.248533Z","signed_message":"canonical_sha256_bytes"},"source_id":"1404.0372","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:418e57deba9d8f98f811052333491acae7f5d6fc9524762bde73edf9a654ab6a","sha256:9dddf7d4f8e6c83a0be8e07f9d35af6e3e954f594273dd7cd133bee6937a7647"],"state_sha256":"baf66cb0666f191cceffc61e13107cd5a2cdb497b6a7d77c44b101932706b491"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Zux+F3X9/bQpb2HDUsCzJ1+rOiIzMo0P8cRgnFpKXV5orEpk0FhzAmWL6gjf+GdXjsDVf09VZv/yLwGs/kYYCw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-02T13:07:34.552769Z","bundle_sha256":"deaa28d147c7e006c09bb284fd017243287d3a648909f3e0cce4b5b7d394c34e"}}