{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2015:GXEFTZMNR4MQ6P363HVNW4AT7J","short_pith_number":"pith:GXEFTZMN","canonical_record":{"source":{"id":"1503.02704","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-03-09T21:28:07Z","cross_cats_sorted":["cond-mat.mes-hall","cond-mat.mtrl-sci","cond-mat.soft","physics.chem-ph"],"title_canon_sha256":"7f8106520eb1f002c63cd0d6fdffcb54b2a66755dd5b6cec8e0b2a818a53af29","abstract_canon_sha256":"c1350781f8f20be2d8e8f0cc2fb092e6fdb208ea370e5cbce2fe494db0193835"},"schema_version":"1.0"},"canonical_sha256":"35c859e58d8f190f3f7ed9eadb7013fa4b7e158d29c11a732304ec80420ee847","source":{"kind":"arxiv","id":"1503.02704","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1503.02704","created_at":"2026-05-18T02:25:17Z"},{"alias_kind":"arxiv_version","alias_value":"1503.02704v1","created_at":"2026-05-18T02:25:17Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1503.02704","created_at":"2026-05-18T02:25:17Z"},{"alias_kind":"pith_short_12","alias_value":"GXEFTZMNR4MQ","created_at":"2026-05-18T12:29:22Z"},{"alias_kind":"pith_short_16","alias_value":"GXEFTZMNR4MQ6P36","created_at":"2026-05-18T12:29:22Z"},{"alias_kind":"pith_short_8","alias_value":"GXEFTZMN","created_at":"2026-05-18T12:29:22Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2015:GXEFTZMNR4MQ6P363HVNW4AT7J","target":"record","payload":{"canonical_record":{"source":{"id":"1503.02704","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-03-09T21:28:07Z","cross_cats_sorted":["cond-mat.mes-hall","cond-mat.mtrl-sci","cond-mat.soft","physics.chem-ph"],"title_canon_sha256":"7f8106520eb1f002c63cd0d6fdffcb54b2a66755dd5b6cec8e0b2a818a53af29","abstract_canon_sha256":"c1350781f8f20be2d8e8f0cc2fb092e6fdb208ea370e5cbce2fe494db0193835"},"schema_version":"1.0"},"canonical_sha256":"35c859e58d8f190f3f7ed9eadb7013fa4b7e158d29c11a732304ec80420ee847","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T02:25:17.993186Z","signature_b64":"3U7PNMieJb9LvqqrOlrkkjOJMgA5cKcDt6HcEuySSnqQZl/H18U9r7p3M21ZwhyRfW7baF9ap9mgwAHa+Xg6DA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"35c859e58d8f190f3f7ed9eadb7013fa4b7e158d29c11a732304ec80420ee847","last_reissued_at":"2026-05-18T02:25:17.992830Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T02:25:17.992830Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1503.02704","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:25:17Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"YNAuc4Wha9gwraNM9j7LWmWplIw5eJ3Dizox+j0MEvFNw6KQTjeLHOsS5E/BirKIueMsxFvUhfGIYQz1V5YaDw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-24T20:06:49.301254Z"},"content_sha256":"91511252a27be146a4454a68eeadd38ca059338561c4d68d7bacfd8b416b6de3","schema_version":"1.0","event_id":"sha256:91511252a27be146a4454a68eeadd38ca059338561c4d68d7bacfd8b416b6de3"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2015:GXEFTZMNR4MQ6P363HVNW4AT7J","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Protein Adsorption into Mesopores: A Combination of Electrostatic Interaction, Counterion Release and van der Waals Forces","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.mes-hall","cond-mat.mtrl-sci","cond-mat.soft","physics.chem-ph"],"primary_cat":"physics.bio-ph","authors_text":"Patrick Huber, Sebastian T. Moerz","submitted_at":"2015-03-09T21:28:07Z","abstract_excerpt":"Bovine heart cytochrome c has been immobilized into the mesoporous silica host material SBA-15 in both its native folded and urea-unfolded state. The comparison of the two folding states' behavior casts doubt on the commonly used explanation of cytochrome c adsorption, i.e. the electrostatic interaction model. A detailed investigation of the protein binding as a function of pH and ionic strength of the buffer solution reveals the complex nature of the protein-silica interaction. Electrostatic interaction, van der Waals forces and entropic contributions by counterion release each contribute to "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1503.02704","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T02:25:17Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"wbWjck31JB1VVPpWNLslNUCHDXAUy+SR9sR1NCMhjlb6VHs8EXcMVjQgvONeTD16PUXquZt9TzGl0YO7hBnHCA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-24T20:06:49.301621Z"},"content_sha256":"b77aece1cec9dea6b034d60b3c40a33bd753bd03454654fb9819587588255909","schema_version":"1.0","event_id":"sha256:b77aece1cec9dea6b034d60b3c40a33bd753bd03454654fb9819587588255909"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/GXEFTZMNR4MQ6P363HVNW4AT7J/bundle.json","state_url":"https://pith.science/pith/GXEFTZMNR4MQ6P363HVNW4AT7J/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/GXEFTZMNR4MQ6P363HVNW4AT7J/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-24T20:06:49Z","links":{"resolver":"https://pith.science/pith/GXEFTZMNR4MQ6P363HVNW4AT7J","bundle":"https://pith.science/pith/GXEFTZMNR4MQ6P363HVNW4AT7J/bundle.json","state":"https://pith.science/pith/GXEFTZMNR4MQ6P363HVNW4AT7J/state.json","well_known_bundle":"https://pith.science/.well-known/pith/GXEFTZMNR4MQ6P363HVNW4AT7J/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2015:GXEFTZMNR4MQ6P363HVNW4AT7J","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"c1350781f8f20be2d8e8f0cc2fb092e6fdb208ea370e5cbce2fe494db0193835","cross_cats_sorted":["cond-mat.mes-hall","cond-mat.mtrl-sci","cond-mat.soft","physics.chem-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-03-09T21:28:07Z","title_canon_sha256":"7f8106520eb1f002c63cd0d6fdffcb54b2a66755dd5b6cec8e0b2a818a53af29"},"schema_version":"1.0","source":{"id":"1503.02704","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1503.02704","created_at":"2026-05-18T02:25:17Z"},{"alias_kind":"arxiv_version","alias_value":"1503.02704v1","created_at":"2026-05-18T02:25:17Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1503.02704","created_at":"2026-05-18T02:25:17Z"},{"alias_kind":"pith_short_12","alias_value":"GXEFTZMNR4MQ","created_at":"2026-05-18T12:29:22Z"},{"alias_kind":"pith_short_16","alias_value":"GXEFTZMNR4MQ6P36","created_at":"2026-05-18T12:29:22Z"},{"alias_kind":"pith_short_8","alias_value":"GXEFTZMN","created_at":"2026-05-18T12:29:22Z"}],"graph_snapshots":[{"event_id":"sha256:b77aece1cec9dea6b034d60b3c40a33bd753bd03454654fb9819587588255909","target":"graph","created_at":"2026-05-18T02:25:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Bovine heart cytochrome c has been immobilized into the mesoporous silica host material SBA-15 in both its native folded and urea-unfolded state. The comparison of the two folding states' behavior casts doubt on the commonly used explanation of cytochrome c adsorption, i.e. the electrostatic interaction model. A detailed investigation of the protein binding as a function of pH and ionic strength of the buffer solution reveals the complex nature of the protein-silica interaction. Electrostatic interaction, van der Waals forces and entropic contributions by counterion release each contribute to ","authors_text":"Patrick Huber, Sebastian T. Moerz","cross_cats":["cond-mat.mes-hall","cond-mat.mtrl-sci","cond-mat.soft","physics.chem-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-03-09T21:28:07Z","title":"Protein Adsorption into Mesopores: A Combination of Electrostatic Interaction, Counterion Release and van der Waals Forces"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1503.02704","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:91511252a27be146a4454a68eeadd38ca059338561c4d68d7bacfd8b416b6de3","target":"record","created_at":"2026-05-18T02:25:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"c1350781f8f20be2d8e8f0cc2fb092e6fdb208ea370e5cbce2fe494db0193835","cross_cats_sorted":["cond-mat.mes-hall","cond-mat.mtrl-sci","cond-mat.soft","physics.chem-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2015-03-09T21:28:07Z","title_canon_sha256":"7f8106520eb1f002c63cd0d6fdffcb54b2a66755dd5b6cec8e0b2a818a53af29"},"schema_version":"1.0","source":{"id":"1503.02704","kind":"arxiv","version":1}},"canonical_sha256":"35c859e58d8f190f3f7ed9eadb7013fa4b7e158d29c11a732304ec80420ee847","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"35c859e58d8f190f3f7ed9eadb7013fa4b7e158d29c11a732304ec80420ee847","first_computed_at":"2026-05-18T02:25:17.992830Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T02:25:17.992830Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"3U7PNMieJb9LvqqrOlrkkjOJMgA5cKcDt6HcEuySSnqQZl/H18U9r7p3M21ZwhyRfW7baF9ap9mgwAHa+Xg6DA==","signature_status":"signed_v1","signed_at":"2026-05-18T02:25:17.993186Z","signed_message":"canonical_sha256_bytes"},"source_id":"1503.02704","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:91511252a27be146a4454a68eeadd38ca059338561c4d68d7bacfd8b416b6de3","sha256:b77aece1cec9dea6b034d60b3c40a33bd753bd03454654fb9819587588255909"],"state_sha256":"ad4850b95b98ba84745ba79ffc939d3135207926a140ddeeba0d77ed40f47f57"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"dTJ04MCXakzNxU1SawSSCv9Jm36EAk8HUjFaRHMcuTI0D3SgEJq248EzCUGkczTdUC1nmraVimYOgw359IscAQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-24T20:06:49.303597Z","bundle_sha256":"19680fe8460e2fb1e3ec12ef638ed92d400a32780543914e83e09f316183b849"}}