{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:H5JC5BQT6YVL33HD5MTP4EVITO","short_pith_number":"pith:H5JC5BQT","canonical_record":{"source":{"id":"1912.00865","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-10-24T20:27:18Z","cross_cats_sorted":[],"title_canon_sha256":"62e92185295998426b11d85cdf24e9794f2f77956c9a7d99a3d4e0da6baefacd","abstract_canon_sha256":"9e376e80b0c60a6256dd94cb5b45997f2fe5e12ee2c70099be23b47e4a716388"},"schema_version":"1.0"},"canonical_sha256":"3f522e8613f62abdece3eb26fe12a89bae69f67c218fcfb690b63170ff1b0146","source":{"kind":"arxiv","id":"1912.00865","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1912.00865","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"arxiv_version","alias_value":"1912.00865v1","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1912.00865","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"pith_short_12","alias_value":"H5JC5BQT6YVL","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"pith_short_16","alias_value":"H5JC5BQT6YVL33HD","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"pith_short_8","alias_value":"H5JC5BQT","created_at":"2026-07-05T00:23:17Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:H5JC5BQT6YVL33HD5MTP4EVITO","target":"record","payload":{"canonical_record":{"source":{"id":"1912.00865","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-10-24T20:27:18Z","cross_cats_sorted":[],"title_canon_sha256":"62e92185295998426b11d85cdf24e9794f2f77956c9a7d99a3d4e0da6baefacd","abstract_canon_sha256":"9e376e80b0c60a6256dd94cb5b45997f2fe5e12ee2c70099be23b47e4a716388"},"schema_version":"1.0"},"canonical_sha256":"3f522e8613f62abdece3eb26fe12a89bae69f67c218fcfb690b63170ff1b0146","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T00:23:17.596049Z","signature_b64":"09Yt0D5N276iVMR6SFQiGcKz5sT0ecoyQqrB85fEPuU1YOBZOszfzlh6X7OhIeZS/JLQVSe0NkBE8wX0iUpjAw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"3f522e8613f62abdece3eb26fe12a89bae69f67c218fcfb690b63170ff1b0146","last_reissued_at":"2026-07-05T00:23:17.595574Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T00:23:17.595574Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1912.00865","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T00:23:17Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"wMZTR4RuI8GGPUkBhPHVjBzslVSlhylte7fxb3JN4pN2AlVACexLA6pbRkqyNSJGeN3tihC+YO7rEWad/ap9DA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-18T11:03:19.174101Z"},"content_sha256":"9e9af3ed72141fe63cd5a090f027454c8f246e1da37312b4d52a20d6c3e77ff5","schema_version":"1.0","event_id":"sha256:9e9af3ed72141fe63cd5a090f027454c8f246e1da37312b4d52a20d6c3e77ff5"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:H5JC5BQT6YVL33HD5MTP4EVITO","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"A Fiber Optoacoustic Emitter with Maximized Conversion Efficiency and Controlled Ultrasound Frequency for Biomedical Applications","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.med-ph","authors_text":"Chen Yang, Ji-Xin Cheng, Linli Shi, Lu Lan, Yimin Huang, Ying Jiang, Yi Zhang","submitted_at":"2019-10-24T20:27:18Z","abstract_excerpt":"Focused ultrasound has attracted great attention in minimally invasive therapy, gene delivery, brain stimulation, etc. Frequency below 1 MHz has been identified preferable for high-efficacy drug delivery, gene transfection and neurostimulation due to minimized tissue heating and cell fragmentation. However, the poor spatial resolution of several millimeters and the large device diameter of ~25 mm of current sub-MHz ultrasound technology severely hinders its further applications for effective, precise, safe and wearable biomedical studies and clinical use. To address this issue, we report the d"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1912.00865","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/1912.00865/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T00:23:17Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"0bSSG9C64OThkDJQoHW3ZCRBPd1F3Bzl+WXvdPh+dKCG7yncMVKMFgxv1RKWSMPy9dirEF679qXNfpgNEX6bCQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-18T11:03:19.174487Z"},"content_sha256":"09499360b29df5e93b4791c2da87dbe4c58fa080e68b192900abef3308b8c03f","schema_version":"1.0","event_id":"sha256:09499360b29df5e93b4791c2da87dbe4c58fa080e68b192900abef3308b8c03f"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/H5JC5BQT6YVL33HD5MTP4EVITO/bundle.json","state_url":"https://pith.science/pith/H5JC5BQT6YVL33HD5MTP4EVITO/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/H5JC5BQT6YVL33HD5MTP4EVITO/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-18T11:03:19Z","links":{"resolver":"https://pith.science/pith/H5JC5BQT6YVL33HD5MTP4EVITO","bundle":"https://pith.science/pith/H5JC5BQT6YVL33HD5MTP4EVITO/bundle.json","state":"https://pith.science/pith/H5JC5BQT6YVL33HD5MTP4EVITO/state.json","well_known_bundle":"https://pith.science/.well-known/pith/H5JC5BQT6YVL33HD5MTP4EVITO/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:H5JC5BQT6YVL33HD5MTP4EVITO","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"9e376e80b0c60a6256dd94cb5b45997f2fe5e12ee2c70099be23b47e4a716388","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-10-24T20:27:18Z","title_canon_sha256":"62e92185295998426b11d85cdf24e9794f2f77956c9a7d99a3d4e0da6baefacd"},"schema_version":"1.0","source":{"id":"1912.00865","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1912.00865","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"arxiv_version","alias_value":"1912.00865v1","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1912.00865","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"pith_short_12","alias_value":"H5JC5BQT6YVL","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"pith_short_16","alias_value":"H5JC5BQT6YVL33HD","created_at":"2026-07-05T00:23:17Z"},{"alias_kind":"pith_short_8","alias_value":"H5JC5BQT","created_at":"2026-07-05T00:23:17Z"}],"graph_snapshots":[{"event_id":"sha256:09499360b29df5e93b4791c2da87dbe4c58fa080e68b192900abef3308b8c03f","target":"graph","created_at":"2026-07-05T00:23:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/1912.00865/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Focused ultrasound has attracted great attention in minimally invasive therapy, gene delivery, brain stimulation, etc. Frequency below 1 MHz has been identified preferable for high-efficacy drug delivery, gene transfection and neurostimulation due to minimized tissue heating and cell fragmentation. However, the poor spatial resolution of several millimeters and the large device diameter of ~25 mm of current sub-MHz ultrasound technology severely hinders its further applications for effective, precise, safe and wearable biomedical studies and clinical use. To address this issue, we report the d","authors_text":"Chen Yang, Ji-Xin Cheng, Linli Shi, Lu Lan, Yimin Huang, Ying Jiang, Yi Zhang","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-10-24T20:27:18Z","title":"A Fiber Optoacoustic Emitter with Maximized Conversion Efficiency and Controlled Ultrasound Frequency for Biomedical Applications"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1912.00865","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:9e9af3ed72141fe63cd5a090f027454c8f246e1da37312b4d52a20d6c3e77ff5","target":"record","created_at":"2026-07-05T00:23:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"9e376e80b0c60a6256dd94cb5b45997f2fe5e12ee2c70099be23b47e4a716388","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-10-24T20:27:18Z","title_canon_sha256":"62e92185295998426b11d85cdf24e9794f2f77956c9a7d99a3d4e0da6baefacd"},"schema_version":"1.0","source":{"id":"1912.00865","kind":"arxiv","version":1}},"canonical_sha256":"3f522e8613f62abdece3eb26fe12a89bae69f67c218fcfb690b63170ff1b0146","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"3f522e8613f62abdece3eb26fe12a89bae69f67c218fcfb690b63170ff1b0146","first_computed_at":"2026-07-05T00:23:17.595574Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T00:23:17.595574Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"09Yt0D5N276iVMR6SFQiGcKz5sT0ecoyQqrB85fEPuU1YOBZOszfzlh6X7OhIeZS/JLQVSe0NkBE8wX0iUpjAw==","signature_status":"signed_v1","signed_at":"2026-07-05T00:23:17.596049Z","signed_message":"canonical_sha256_bytes"},"source_id":"1912.00865","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:9e9af3ed72141fe63cd5a090f027454c8f246e1da37312b4d52a20d6c3e77ff5","sha256:09499360b29df5e93b4791c2da87dbe4c58fa080e68b192900abef3308b8c03f"],"state_sha256":"39a1fb269b594da8c58e73cf8a17477b5da098c669bc3e7ad0a47b64db53bf21"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"RVY9wqJvMUDEuqn8Q/8u/5DdtGsoWUXq7s1Oa36bZEKywmFA8En56ZBXbinFdEzyvBFa5R91FWZxqcWQS+FHAA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-18T11:03:19.176650Z","bundle_sha256":"52a065dfe576e6010a810370807d477ae5b592dc45efcefa5fa18d766c67ae04"}}