{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2025:HESM7PAAMKUXHM7D4IHVXFXJTL","short_pith_number":"pith:HESM7PAA","canonical_record":{"source":{"id":"2506.14540","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.LG","submitted_at":"2025-06-17T14:01:39Z","cross_cats_sorted":["cs.AI"],"title_canon_sha256":"1a0d57271c3710eda46cbd969e88ddc4b22401fc2732c39723621f6844acaba5","abstract_canon_sha256":"c4b82477d1769243c3a1e17f79af760fb92066f14cd5cf39f200edbe01cdf3ca"},"schema_version":"1.0"},"canonical_sha256":"3924cfbc0062a973b3e3e20f5b96e99af1dadebabfcac9157d02ba3208c82d9a","source":{"kind":"arxiv","id":"2506.14540","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2506.14540","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"arxiv_version","alias_value":"2506.14540v3","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2506.14540","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"pith_short_12","alias_value":"HESM7PAAMKUX","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"pith_short_16","alias_value":"HESM7PAAMKUXHM7D","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"pith_short_8","alias_value":"HESM7PAA","created_at":"2026-07-05T11:29:13Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2025:HESM7PAAMKUXHM7D4IHVXFXJTL","target":"record","payload":{"canonical_record":{"source":{"id":"2506.14540","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.LG","submitted_at":"2025-06-17T14:01:39Z","cross_cats_sorted":["cs.AI"],"title_canon_sha256":"1a0d57271c3710eda46cbd969e88ddc4b22401fc2732c39723621f6844acaba5","abstract_canon_sha256":"c4b82477d1769243c3a1e17f79af760fb92066f14cd5cf39f200edbe01cdf3ca"},"schema_version":"1.0"},"canonical_sha256":"3924cfbc0062a973b3e3e20f5b96e99af1dadebabfcac9157d02ba3208c82d9a","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T11:29:13.342501Z","signature_b64":"MPV8ZsHvndkdQUdM8+V0lLlHL4lpTyaptDkA5DoMUHkUJqYt+ybGtLOIDBnyXkrpT2a8SurHNDlj/JLWXYHNCQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"3924cfbc0062a973b3e3e20f5b96e99af1dadebabfcac9157d02ba3208c82d9a","last_reissued_at":"2026-07-05T11:29:13.342012Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T11:29:13.342012Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2506.14540","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T11:29:13Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"UMCqXkhwEM7DkdThdYLfnayvyIg5Ix8fp4h4CTbPPI51cchQzoR1PVDC5eW+OUDwhf+l5AF7s1rk4P36D/JjBw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-08T14:12:27.526614Z"},"content_sha256":"f3f396d56204df4e58b2f829be9fb7a43bb56b9a33b0df06ee6c53e659d94e21","schema_version":"1.0","event_id":"sha256:f3f396d56204df4e58b2f829be9fb7a43bb56b9a33b0df06ee6c53e659d94e21"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2025:HESM7PAAMKUXHM7D4IHVXFXJTL","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Aligning Evaluation with Clinical Priorities: Calibration, Label Shift, and Error Costs","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.AI"],"primary_cat":"cs.LG","authors_text":"Alyssa H. Smith, Ashia C. Wilson, Gerardo A. Flores, Julia A. Fukuyama","submitted_at":"2025-06-17T14:01:39Z","abstract_excerpt":"Machine learning-based decision support systems are increasingly deployed in clinical settings, where probabilistic scoring functions are used to inform and prioritize patient management decisions. However, widely used scoring rules, such as accuracy and AUC-ROC, fail to adequately reflect key clinical priorities, including calibration, robustness to distributional shifts, and sensitivity to asymmetric error costs. In this work, we propose a principled yet practical evaluation framework for selecting calibrated thresholded classifiers that explicitly accounts for the uncertainty in class preva"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2506.14540","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2506.14540/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T11:29:13Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"1dBfQIivYV34JiW4e/8QiVUwmdH+m6Wkvv/anoi/lGOUlvCuQTPZRDOB6RMfNqYCY2LIeY+6CKNQkjCh8jgvBg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-08T14:12:27.527262Z"},"content_sha256":"87667198dfe99801eabd31bd67512ef5e878866df9e29de09f3a6be61628250d","schema_version":"1.0","event_id":"sha256:87667198dfe99801eabd31bd67512ef5e878866df9e29de09f3a6be61628250d"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/HESM7PAAMKUXHM7D4IHVXFXJTL/bundle.json","state_url":"https://pith.science/pith/HESM7PAAMKUXHM7D4IHVXFXJTL/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/HESM7PAAMKUXHM7D4IHVXFXJTL/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-08T14:12:27Z","links":{"resolver":"https://pith.science/pith/HESM7PAAMKUXHM7D4IHVXFXJTL","bundle":"https://pith.science/pith/HESM7PAAMKUXHM7D4IHVXFXJTL/bundle.json","state":"https://pith.science/pith/HESM7PAAMKUXHM7D4IHVXFXJTL/state.json","well_known_bundle":"https://pith.science/.well-known/pith/HESM7PAAMKUXHM7D4IHVXFXJTL/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2025:HESM7PAAMKUXHM7D4IHVXFXJTL","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"c4b82477d1769243c3a1e17f79af760fb92066f14cd5cf39f200edbe01cdf3ca","cross_cats_sorted":["cs.AI"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.LG","submitted_at":"2025-06-17T14:01:39Z","title_canon_sha256":"1a0d57271c3710eda46cbd969e88ddc4b22401fc2732c39723621f6844acaba5"},"schema_version":"1.0","source":{"id":"2506.14540","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2506.14540","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"arxiv_version","alias_value":"2506.14540v3","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2506.14540","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"pith_short_12","alias_value":"HESM7PAAMKUX","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"pith_short_16","alias_value":"HESM7PAAMKUXHM7D","created_at":"2026-07-05T11:29:13Z"},{"alias_kind":"pith_short_8","alias_value":"HESM7PAA","created_at":"2026-07-05T11:29:13Z"}],"graph_snapshots":[{"event_id":"sha256:87667198dfe99801eabd31bd67512ef5e878866df9e29de09f3a6be61628250d","target":"graph","created_at":"2026-07-05T11:29:13Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2506.14540/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Machine learning-based decision support systems are increasingly deployed in clinical settings, where probabilistic scoring functions are used to inform and prioritize patient management decisions. However, widely used scoring rules, such as accuracy and AUC-ROC, fail to adequately reflect key clinical priorities, including calibration, robustness to distributional shifts, and sensitivity to asymmetric error costs. In this work, we propose a principled yet practical evaluation framework for selecting calibrated thresholded classifiers that explicitly accounts for the uncertainty in class preva","authors_text":"Alyssa H. Smith, Ashia C. Wilson, Gerardo A. Flores, Julia A. Fukuyama","cross_cats":["cs.AI"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.LG","submitted_at":"2025-06-17T14:01:39Z","title":"Aligning Evaluation with Clinical Priorities: Calibration, Label Shift, and Error Costs"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2506.14540","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:f3f396d56204df4e58b2f829be9fb7a43bb56b9a33b0df06ee6c53e659d94e21","target":"record","created_at":"2026-07-05T11:29:13Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"c4b82477d1769243c3a1e17f79af760fb92066f14cd5cf39f200edbe01cdf3ca","cross_cats_sorted":["cs.AI"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.LG","submitted_at":"2025-06-17T14:01:39Z","title_canon_sha256":"1a0d57271c3710eda46cbd969e88ddc4b22401fc2732c39723621f6844acaba5"},"schema_version":"1.0","source":{"id":"2506.14540","kind":"arxiv","version":3}},"canonical_sha256":"3924cfbc0062a973b3e3e20f5b96e99af1dadebabfcac9157d02ba3208c82d9a","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"3924cfbc0062a973b3e3e20f5b96e99af1dadebabfcac9157d02ba3208c82d9a","first_computed_at":"2026-07-05T11:29:13.342012Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T11:29:13.342012Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"MPV8ZsHvndkdQUdM8+V0lLlHL4lpTyaptDkA5DoMUHkUJqYt+ybGtLOIDBnyXkrpT2a8SurHNDlj/JLWXYHNCQ==","signature_status":"signed_v1","signed_at":"2026-07-05T11:29:13.342501Z","signed_message":"canonical_sha256_bytes"},"source_id":"2506.14540","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:f3f396d56204df4e58b2f829be9fb7a43bb56b9a33b0df06ee6c53e659d94e21","sha256:87667198dfe99801eabd31bd67512ef5e878866df9e29de09f3a6be61628250d"],"state_sha256":"945af931f50a90d124aae109e129f97e2f6fc9840880e3f97f6fb2f72f460a04"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"A5dl+6mJ09w1HPfwSgPFhBhBJ97GOxXFyuJDE+fLgGMvBxqlWodTYp9/fzJNGvQhWdYUfmZGhdkcAgmZeeJpBw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-08T14:12:27.533024Z","bundle_sha256":"af72386c8ae318b1eb8b8791cce2e3f7bc5127c444cbeabb0cfd943d9c8150a3"}}