{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2015:HF2ZY5NVJAWJSQIY3UXAAIMG5P","short_pith_number":"pith:HF2ZY5NV","canonical_record":{"source":{"id":"1506.06913","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-23T09:05:07Z","cross_cats_sorted":["physics.bio-ph","physics.optics"],"title_canon_sha256":"c0f3755eb11bb4efc0cf962821a151ceed4edaf9975fe2992dc6d0d55fe28943","abstract_canon_sha256":"7dac326ac05134fb7a7675aa8debeb9cc9894ad63115c577bec1cc05071ec177"},"schema_version":"1.0"},"canonical_sha256":"39759c75b5482c994118dd2e002186ebfb27b8bb7d4152592319f443575eb418","source":{"kind":"arxiv","id":"1506.06913","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1506.06913","created_at":"2026-05-18T01:40:55Z"},{"alias_kind":"arxiv_version","alias_value":"1506.06913v1","created_at":"2026-05-18T01:40:55Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1506.06913","created_at":"2026-05-18T01:40:55Z"},{"alias_kind":"pith_short_12","alias_value":"HF2ZY5NVJAWJ","created_at":"2026-05-18T12:29:25Z"},{"alias_kind":"pith_short_16","alias_value":"HF2ZY5NVJAWJSQIY","created_at":"2026-05-18T12:29:25Z"},{"alias_kind":"pith_short_8","alias_value":"HF2ZY5NV","created_at":"2026-05-18T12:29:25Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2015:HF2ZY5NVJAWJSQIY3UXAAIMG5P","target":"record","payload":{"canonical_record":{"source":{"id":"1506.06913","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-23T09:05:07Z","cross_cats_sorted":["physics.bio-ph","physics.optics"],"title_canon_sha256":"c0f3755eb11bb4efc0cf962821a151ceed4edaf9975fe2992dc6d0d55fe28943","abstract_canon_sha256":"7dac326ac05134fb7a7675aa8debeb9cc9894ad63115c577bec1cc05071ec177"},"schema_version":"1.0"},"canonical_sha256":"39759c75b5482c994118dd2e002186ebfb27b8bb7d4152592319f443575eb418","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:40:55.614791Z","signature_b64":"BWqzvqVryAffX3Z29haiRl8NS+kErQNqqjnWx+31no+8Je7Mw+9zGcNSwA6s5W1/pOGyjrkMLj1NiDhrIGGnAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"39759c75b5482c994118dd2e002186ebfb27b8bb7d4152592319f443575eb418","last_reissued_at":"2026-05-18T01:40:55.614140Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:40:55.614140Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1506.06913","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:40:55Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"5tankZ/AY2k92WhqQSdnJjWySHA0J9RW7s50o7RqaHegsFbsfuGuxNqAkuHcEHF6opj6lIPCxUgkaIF+c0OiDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T18:26:15.106428Z"},"content_sha256":"c1b83754a003741fb7d04a8b713408688886aaa48665c43ade90ab1cdb5b8fb3","schema_version":"1.0","event_id":"sha256:c1b83754a003741fb7d04a8b713408688886aaa48665c43ade90ab1cdb5b8fb3"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2015:HF2ZY5NVJAWJSQIY3UXAAIMG5P","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Developing a new biophysical tool to combine magneto-optical tweezers with super-resolution fluorescence microscopy","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph","physics.optics"],"primary_cat":"q-bio.BM","authors_text":"Adam J. M. Wollman, Helen Miller, Mark C. Leake, Zhaokun Zhou","submitted_at":"2015-06-23T09:05:07Z","abstract_excerpt":"We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and manipulation. Previously we have developed a super-resolution imaging module which in conjunction with advanced imaging techniques such as Blinking assisted Localisation Microscopy (BaLM) achieves localisation precision of single fluorescent dye molecules bound to DNA of ~30 nm along the contour of the molecule; our work here describes developments in producing"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1506.06913","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:40:55Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"tChPZ+wfdxms1R9pU7TSgFPg9p0wLhKIPFxvJ5hpScMRz8TCEfzOlgsWlFHAfGV2Zmrv4lQxgg+bVEM8TmXiDg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T18:26:15.107076Z"},"content_sha256":"9679d9b0ec6e67678391c88548ec7a22fdccfbf5ff94dc8d6b6560db0de614b5","schema_version":"1.0","event_id":"sha256:9679d9b0ec6e67678391c88548ec7a22fdccfbf5ff94dc8d6b6560db0de614b5"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/HF2ZY5NVJAWJSQIY3UXAAIMG5P/bundle.json","state_url":"https://pith.science/pith/HF2ZY5NVJAWJSQIY3UXAAIMG5P/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/HF2ZY5NVJAWJSQIY3UXAAIMG5P/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T18:26:15Z","links":{"resolver":"https://pith.science/pith/HF2ZY5NVJAWJSQIY3UXAAIMG5P","bundle":"https://pith.science/pith/HF2ZY5NVJAWJSQIY3UXAAIMG5P/bundle.json","state":"https://pith.science/pith/HF2ZY5NVJAWJSQIY3UXAAIMG5P/state.json","well_known_bundle":"https://pith.science/.well-known/pith/HF2ZY5NVJAWJSQIY3UXAAIMG5P/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2015:HF2ZY5NVJAWJSQIY3UXAAIMG5P","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"7dac326ac05134fb7a7675aa8debeb9cc9894ad63115c577bec1cc05071ec177","cross_cats_sorted":["physics.bio-ph","physics.optics"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-23T09:05:07Z","title_canon_sha256":"c0f3755eb11bb4efc0cf962821a151ceed4edaf9975fe2992dc6d0d55fe28943"},"schema_version":"1.0","source":{"id":"1506.06913","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1506.06913","created_at":"2026-05-18T01:40:55Z"},{"alias_kind":"arxiv_version","alias_value":"1506.06913v1","created_at":"2026-05-18T01:40:55Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1506.06913","created_at":"2026-05-18T01:40:55Z"},{"alias_kind":"pith_short_12","alias_value":"HF2ZY5NVJAWJ","created_at":"2026-05-18T12:29:25Z"},{"alias_kind":"pith_short_16","alias_value":"HF2ZY5NVJAWJSQIY","created_at":"2026-05-18T12:29:25Z"},{"alias_kind":"pith_short_8","alias_value":"HF2ZY5NV","created_at":"2026-05-18T12:29:25Z"}],"graph_snapshots":[{"event_id":"sha256:9679d9b0ec6e67678391c88548ec7a22fdccfbf5ff94dc8d6b6560db0de614b5","target":"graph","created_at":"2026-05-18T01:40:55Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and manipulation. Previously we have developed a super-resolution imaging module which in conjunction with advanced imaging techniques such as Blinking assisted Localisation Microscopy (BaLM) achieves localisation precision of single fluorescent dye molecules bound to DNA of ~30 nm along the contour of the molecule; our work here describes developments in producing","authors_text":"Adam J. M. Wollman, Helen Miller, Mark C. Leake, Zhaokun Zhou","cross_cats":["physics.bio-ph","physics.optics"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-23T09:05:07Z","title":"Developing a new biophysical tool to combine magneto-optical tweezers with super-resolution fluorescence microscopy"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1506.06913","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:c1b83754a003741fb7d04a8b713408688886aaa48665c43ade90ab1cdb5b8fb3","target":"record","created_at":"2026-05-18T01:40:55Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"7dac326ac05134fb7a7675aa8debeb9cc9894ad63115c577bec1cc05071ec177","cross_cats_sorted":["physics.bio-ph","physics.optics"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2015-06-23T09:05:07Z","title_canon_sha256":"c0f3755eb11bb4efc0cf962821a151ceed4edaf9975fe2992dc6d0d55fe28943"},"schema_version":"1.0","source":{"id":"1506.06913","kind":"arxiv","version":1}},"canonical_sha256":"39759c75b5482c994118dd2e002186ebfb27b8bb7d4152592319f443575eb418","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"39759c75b5482c994118dd2e002186ebfb27b8bb7d4152592319f443575eb418","first_computed_at":"2026-05-18T01:40:55.614140Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:40:55.614140Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"BWqzvqVryAffX3Z29haiRl8NS+kErQNqqjnWx+31no+8Je7Mw+9zGcNSwA6s5W1/pOGyjrkMLj1NiDhrIGGnAg==","signature_status":"signed_v1","signed_at":"2026-05-18T01:40:55.614791Z","signed_message":"canonical_sha256_bytes"},"source_id":"1506.06913","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:c1b83754a003741fb7d04a8b713408688886aaa48665c43ade90ab1cdb5b8fb3","sha256:9679d9b0ec6e67678391c88548ec7a22fdccfbf5ff94dc8d6b6560db0de614b5"],"state_sha256":"58f688b65bc3732775b9dcd6c2dcd7b7cf8a9320032749c73a3cb62380691dfe"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"LehzpUJUoTI0hbWL5pc7vM+dZSX2o4eITq0HjCah9RpG/sMfr0GpncsiCENXTKAT14lSE27hdaWdWLPjf8PtAw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T18:26:15.110292Z","bundle_sha256":"3f8f7191e94660c39a95367fabccc6ebe04cf8a2df28518902bd77f11bc1e4c1"}}