{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2019:HK3QH7TZ6KYNPCQLGUBCFMUFOU","short_pith_number":"pith:HK3QH7TZ","schema_version":"1.0","canonical_sha256":"3ab703fe79f2b0d78a0b350222b285751dd4cd59217b8cff8c1fd745104ada28","source":{"kind":"arxiv","id":"1904.11809","version":1},"attestation_state":"computed","paper":{"title":"Photoacoustic monitoring of blood oxygenation during neurosurgical interventions","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.med-ph","authors_text":"Adri\\'an Hern\\'andez-Aguilera, Edgar Santos, Janek Gr\\\"ohl, Lena Maier-Hein, Mildred A. Herrera, Niklas Holzwarth, Thomas Kirchner, Tim Adler","submitted_at":"2019-04-26T12:47:43Z","abstract_excerpt":"Multispectral photoacoustic (PA) imaging is a prime modality to monitor hemodynamics and changes in blood oxygenation (sO2). Although sO2 changes can be an indicator of brain activity both in normal and in pathological conditions, PA imaging of the brain has mainly focused on small animal models with lissencephalic brains. Therefore, the purpose of this work was to investigate the usefulness of multispectral PA imaging in assessing sO2 in a gyrencephalic brain. To this end, we continuously imaged a porcine brain as part of an open neurosurgical intervention with a handheld PA and ultrasonic (U"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1904.11809","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-04-26T12:47:43Z","cross_cats_sorted":[],"title_canon_sha256":"28c9c141cf41e1783012cf7bc3c585849b2e7e1b4c836921d027f6df2e9290be","abstract_canon_sha256":"05f8b44a2516495537f90570fe78f3383f339793621a407667b319f8cfe33ef8"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:47:40.866255Z","signature_b64":"RLILLVNOI89WYnBtjMbMr9N8mDGKL2zNhvuvPSJado5AEYbZl3fqzqKuKo+5Ew61Moi69me49KiysLqWhi9aCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"3ab703fe79f2b0d78a0b350222b285751dd4cd59217b8cff8c1fd745104ada28","last_reissued_at":"2026-05-17T23:47:40.865794Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:47:40.865794Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Photoacoustic monitoring of blood oxygenation during neurosurgical interventions","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.med-ph","authors_text":"Adri\\'an Hern\\'andez-Aguilera, Edgar Santos, Janek Gr\\\"ohl, Lena Maier-Hein, Mildred A. Herrera, Niklas Holzwarth, Thomas Kirchner, Tim Adler","submitted_at":"2019-04-26T12:47:43Z","abstract_excerpt":"Multispectral photoacoustic (PA) imaging is a prime modality to monitor hemodynamics and changes in blood oxygenation (sO2). Although sO2 changes can be an indicator of brain activity both in normal and in pathological conditions, PA imaging of the brain has mainly focused on small animal models with lissencephalic brains. Therefore, the purpose of this work was to investigate the usefulness of multispectral PA imaging in assessing sO2 in a gyrencephalic brain. To this end, we continuously imaged a porcine brain as part of an open neurosurgical intervention with a handheld PA and ultrasonic (U"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1904.11809","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1904.11809","created_at":"2026-05-17T23:47:40.865870+00:00"},{"alias_kind":"arxiv_version","alias_value":"1904.11809v1","created_at":"2026-05-17T23:47:40.865870+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1904.11809","created_at":"2026-05-17T23:47:40.865870+00:00"},{"alias_kind":"pith_short_12","alias_value":"HK3QH7TZ6KYN","created_at":"2026-05-18T12:33:18.533446+00:00"},{"alias_kind":"pith_short_16","alias_value":"HK3QH7TZ6KYNPCQL","created_at":"2026-05-18T12:33:18.533446+00:00"},{"alias_kind":"pith_short_8","alias_value":"HK3QH7TZ","created_at":"2026-05-18T12:33:18.533446+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/HK3QH7TZ6KYNPCQLGUBCFMUFOU","json":"https://pith.science/pith/HK3QH7TZ6KYNPCQLGUBCFMUFOU.json","graph_json":"https://pith.science/api/pith-number/HK3QH7TZ6KYNPCQLGUBCFMUFOU/graph.json","events_json":"https://pith.science/api/pith-number/HK3QH7TZ6KYNPCQLGUBCFMUFOU/events.json","paper":"https://pith.science/paper/HK3QH7TZ"},"agent_actions":{"view_html":"https://pith.science/pith/HK3QH7TZ6KYNPCQLGUBCFMUFOU","download_json":"https://pith.science/pith/HK3QH7TZ6KYNPCQLGUBCFMUFOU.json","view_paper":"https://pith.science/paper/HK3QH7TZ","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1904.11809&json=true","fetch_graph":"https://pith.science/api/pith-number/HK3QH7TZ6KYNPCQLGUBCFMUFOU/graph.json","fetch_events":"https://pith.science/api/pith-number/HK3QH7TZ6KYNPCQLGUBCFMUFOU/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/HK3QH7TZ6KYNPCQLGUBCFMUFOU/action/timestamp_anchor","attest_storage":"https://pith.science/pith/HK3QH7TZ6KYNPCQLGUBCFMUFOU/action/storage_attestation","attest_author":"https://pith.science/pith/HK3QH7TZ6KYNPCQLGUBCFMUFOU/action/author_attestation","sign_citation":"https://pith.science/pith/HK3QH7TZ6KYNPCQLGUBCFMUFOU/action/citation_signature","submit_replication":"https://pith.science/pith/HK3QH7TZ6KYNPCQLGUBCFMUFOU/action/replication_record"}},"created_at":"2026-05-17T23:47:40.865870+00:00","updated_at":"2026-05-17T23:47:40.865870+00:00"}