{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:HTVD6MXVRIG4EPG4MWWO5CZ7VM","short_pith_number":"pith:HTVD6MXV","canonical_record":{"source":{"id":"1604.04484","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-04-15T13:06:47Z","cross_cats_sorted":["stat.AP"],"title_canon_sha256":"c653c10b892a21ace68bc6f56f296f03ad7156ac62f6752e0109742027805dda","abstract_canon_sha256":"907ef71a24486ab68e8c676fc5668004fdb2b155e45e5bac00e68257f80e2347"},"schema_version":"1.0"},"canonical_sha256":"3cea3f32f58a0dc23cdc65acee8b3fab0a997f6a44984e7efaf5fd6dccaa89d5","source":{"kind":"arxiv","id":"1604.04484","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1604.04484","created_at":"2026-05-18T01:17:02Z"},{"alias_kind":"arxiv_version","alias_value":"1604.04484v1","created_at":"2026-05-18T01:17:02Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1604.04484","created_at":"2026-05-18T01:17:02Z"},{"alias_kind":"pith_short_12","alias_value":"HTVD6MXVRIG4","created_at":"2026-05-18T12:30:22Z"},{"alias_kind":"pith_short_16","alias_value":"HTVD6MXVRIG4EPG4","created_at":"2026-05-18T12:30:22Z"},{"alias_kind":"pith_short_8","alias_value":"HTVD6MXV","created_at":"2026-05-18T12:30:22Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:HTVD6MXVRIG4EPG4MWWO5CZ7VM","target":"record","payload":{"canonical_record":{"source":{"id":"1604.04484","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-04-15T13:06:47Z","cross_cats_sorted":["stat.AP"],"title_canon_sha256":"c653c10b892a21ace68bc6f56f296f03ad7156ac62f6752e0109742027805dda","abstract_canon_sha256":"907ef71a24486ab68e8c676fc5668004fdb2b155e45e5bac00e68257f80e2347"},"schema_version":"1.0"},"canonical_sha256":"3cea3f32f58a0dc23cdc65acee8b3fab0a997f6a44984e7efaf5fd6dccaa89d5","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:17:02.033081Z","signature_b64":"oIn+2cL8a6v7hs8xMHYP5PeflDGQa/lQcqK1PG06JKmw4QYBbk/I+Ic0LpUI3p8DrUPQQS/uAjtp0DW7jFWSCQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"3cea3f32f58a0dc23cdc65acee8b3fab0a997f6a44984e7efaf5fd6dccaa89d5","last_reissued_at":"2026-05-18T01:17:02.032347Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:17:02.032347Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1604.04484","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:17:02Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"FLuCXw7YNe7aBPcDc0cAddzHBXRvLed+8WPg9Bed719Z9d9f5P3PXwyJ9rGNi4hTdaZlOQGop8nKUtMworSgBg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-22T02:29:11.974654Z"},"content_sha256":"60746a89c400f7da2c405a899a1a22e4eb38851c1126d46fc23e92814c80e79e","schema_version":"1.0","event_id":"sha256:60746a89c400f7da2c405a899a1a22e4eb38851c1126d46fc23e92814c80e79e"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:HTVD6MXVRIG4EPG4MWWO5CZ7VM","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Enabling Privacy-Preserving GWAS in Heterogeneous Human Populations","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["stat.AP"],"primary_cat":"q-bio.QM","authors_text":"Bonnie Berger, Cenk Sahinalp, Sean Simmons","submitted_at":"2016-04-15T13:06:47Z","abstract_excerpt":"The projected increase of genotyping in the clinic and the rise of large genomic databases has led to the possibility of using patient medical data to perform genomewide association studies (GWAS) on a larger scale and at a lower cost than ever before. Due to privacy concerns, however, access to this data is limited to a few trusted individuals, greatly reducing its impact on biomedical research. Privacy preserving methods have been suggested as a way of allowing more people access to this precious data while protecting patients. In particular, there has been growing interest in applying the c"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1604.04484","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:17:02Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"yuLBXnmgRT+j1/7cAGQynyRqMWfUiwajx+ScVERwiZYN/AWnrNkCkOI9R/bvWAlXelJdyOIwSLwSFXZ2SDgtCQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-22T02:29:11.975261Z"},"content_sha256":"dfe4cc0d254c1a217af2c05295ca942259f5b5c788c73a4eeafd5388da6c832a","schema_version":"1.0","event_id":"sha256:dfe4cc0d254c1a217af2c05295ca942259f5b5c788c73a4eeafd5388da6c832a"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/HTVD6MXVRIG4EPG4MWWO5CZ7VM/bundle.json","state_url":"https://pith.science/pith/HTVD6MXVRIG4EPG4MWWO5CZ7VM/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/HTVD6MXVRIG4EPG4MWWO5CZ7VM/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-22T02:29:11Z","links":{"resolver":"https://pith.science/pith/HTVD6MXVRIG4EPG4MWWO5CZ7VM","bundle":"https://pith.science/pith/HTVD6MXVRIG4EPG4MWWO5CZ7VM/bundle.json","state":"https://pith.science/pith/HTVD6MXVRIG4EPG4MWWO5CZ7VM/state.json","well_known_bundle":"https://pith.science/.well-known/pith/HTVD6MXVRIG4EPG4MWWO5CZ7VM/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:HTVD6MXVRIG4EPG4MWWO5CZ7VM","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"907ef71a24486ab68e8c676fc5668004fdb2b155e45e5bac00e68257f80e2347","cross_cats_sorted":["stat.AP"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-04-15T13:06:47Z","title_canon_sha256":"c653c10b892a21ace68bc6f56f296f03ad7156ac62f6752e0109742027805dda"},"schema_version":"1.0","source":{"id":"1604.04484","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1604.04484","created_at":"2026-05-18T01:17:02Z"},{"alias_kind":"arxiv_version","alias_value":"1604.04484v1","created_at":"2026-05-18T01:17:02Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1604.04484","created_at":"2026-05-18T01:17:02Z"},{"alias_kind":"pith_short_12","alias_value":"HTVD6MXVRIG4","created_at":"2026-05-18T12:30:22Z"},{"alias_kind":"pith_short_16","alias_value":"HTVD6MXVRIG4EPG4","created_at":"2026-05-18T12:30:22Z"},{"alias_kind":"pith_short_8","alias_value":"HTVD6MXV","created_at":"2026-05-18T12:30:22Z"}],"graph_snapshots":[{"event_id":"sha256:dfe4cc0d254c1a217af2c05295ca942259f5b5c788c73a4eeafd5388da6c832a","target":"graph","created_at":"2026-05-18T01:17:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The projected increase of genotyping in the clinic and the rise of large genomic databases has led to the possibility of using patient medical data to perform genomewide association studies (GWAS) on a larger scale and at a lower cost than ever before. Due to privacy concerns, however, access to this data is limited to a few trusted individuals, greatly reducing its impact on biomedical research. Privacy preserving methods have been suggested as a way of allowing more people access to this precious data while protecting patients. In particular, there has been growing interest in applying the c","authors_text":"Bonnie Berger, Cenk Sahinalp, Sean Simmons","cross_cats":["stat.AP"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-04-15T13:06:47Z","title":"Enabling Privacy-Preserving GWAS in Heterogeneous Human Populations"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1604.04484","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:60746a89c400f7da2c405a899a1a22e4eb38851c1126d46fc23e92814c80e79e","target":"record","created_at":"2026-05-18T01:17:02Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"907ef71a24486ab68e8c676fc5668004fdb2b155e45e5bac00e68257f80e2347","cross_cats_sorted":["stat.AP"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2016-04-15T13:06:47Z","title_canon_sha256":"c653c10b892a21ace68bc6f56f296f03ad7156ac62f6752e0109742027805dda"},"schema_version":"1.0","source":{"id":"1604.04484","kind":"arxiv","version":1}},"canonical_sha256":"3cea3f32f58a0dc23cdc65acee8b3fab0a997f6a44984e7efaf5fd6dccaa89d5","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"3cea3f32f58a0dc23cdc65acee8b3fab0a997f6a44984e7efaf5fd6dccaa89d5","first_computed_at":"2026-05-18T01:17:02.032347Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:17:02.032347Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"oIn+2cL8a6v7hs8xMHYP5PeflDGQa/lQcqK1PG06JKmw4QYBbk/I+Ic0LpUI3p8DrUPQQS/uAjtp0DW7jFWSCQ==","signature_status":"signed_v1","signed_at":"2026-05-18T01:17:02.033081Z","signed_message":"canonical_sha256_bytes"},"source_id":"1604.04484","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:60746a89c400f7da2c405a899a1a22e4eb38851c1126d46fc23e92814c80e79e","sha256:dfe4cc0d254c1a217af2c05295ca942259f5b5c788c73a4eeafd5388da6c832a"],"state_sha256":"df49c85aa5a4763e52b04d45da5370faaf25c1a03259905599d220242d9d34dd"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"oPC8Fl+Mgtx1ZnZqvR5/QVOQk7Sag7eVzgLpVwTqvWZdg0FwxkJQ8hIUJByZnZufjUK+KKN730hRIuiNrcIaBw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-22T02:29:11.977550Z","bundle_sha256":"2d3a0899d71031deaa4a1f7b367d0e41ab7a0a6a736956ac1002f89643d7e04d"}}