{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2015:I37HCE4S72VJFWXK6I2LX7SBIK","short_pith_number":"pith:I37HCE4S","schema_version":"1.0","canonical_sha256":"46fe711392feaa92daeaf234bbfe4142aff9d1cf71d148025d467027fb754783","source":{"kind":"arxiv","id":"1508.02930","version":1},"attestation_state":"computed","paper":{"title":"End-to-End Optimization of High Throughput DNA Sequencing","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["math.PR"],"primary_cat":"q-bio.GN","authors_text":"Eliza O'Reilly, Francois Baccelli, Gustavo de Veciana, Haris Vikalo","submitted_at":"2015-08-04T13:50:52Z","abstract_excerpt":"At the core of high throughput DNA sequencing platforms lies a bio-physical surface process that results in a random geometry of clusters of homogenous short DNA fragments typically hundreds of base pairs long - bridge amplification. The statistical properties of this random process and length of the fragments are critical as they affect the information that can be subsequently extracted, i.e., density of successfully inferred DNA fragment reads. The ensemble of overlapping DNA fragment reads are then used to computationally reconstruct the much longer target genome sequence, e.g, ranging from"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1508.02930","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.GN","submitted_at":"2015-08-04T13:50:52Z","cross_cats_sorted":["math.PR"],"title_canon_sha256":"f35ea8155e80e3e79e6ff9e8ee49157a87ad03e1ce6371d0943314db6c1face9","abstract_canon_sha256":"5d41d31d4a61f830a3c045349130d53d90150540c45931b5f22f1d432bde2842"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:35:23.411415Z","signature_b64":"xiNhtpfdxQpMJuUNM9TjVWnwMeKZSqTkxTqS03IgCToiTvZwbAsTsjrQqFLH4KwVwyaHRqJq2aljopfZ4zw8DQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"46fe711392feaa92daeaf234bbfe4142aff9d1cf71d148025d467027fb754783","last_reissued_at":"2026-05-18T01:35:23.410654Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:35:23.410654Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"End-to-End Optimization of High Throughput DNA Sequencing","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["math.PR"],"primary_cat":"q-bio.GN","authors_text":"Eliza O'Reilly, Francois Baccelli, Gustavo de Veciana, Haris Vikalo","submitted_at":"2015-08-04T13:50:52Z","abstract_excerpt":"At the core of high throughput DNA sequencing platforms lies a bio-physical surface process that results in a random geometry of clusters of homogenous short DNA fragments typically hundreds of base pairs long - bridge amplification. The statistical properties of this random process and length of the fragments are critical as they affect the information that can be subsequently extracted, i.e., density of successfully inferred DNA fragment reads. The ensemble of overlapping DNA fragment reads are then used to computationally reconstruct the much longer target genome sequence, e.g, ranging from"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1508.02930","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1508.02930","created_at":"2026-05-18T01:35:23.410776+00:00"},{"alias_kind":"arxiv_version","alias_value":"1508.02930v1","created_at":"2026-05-18T01:35:23.410776+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1508.02930","created_at":"2026-05-18T01:35:23.410776+00:00"},{"alias_kind":"pith_short_12","alias_value":"I37HCE4S72VJ","created_at":"2026-05-18T12:29:25.134429+00:00"},{"alias_kind":"pith_short_16","alias_value":"I37HCE4S72VJFWXK","created_at":"2026-05-18T12:29:25.134429+00:00"},{"alias_kind":"pith_short_8","alias_value":"I37HCE4S","created_at":"2026-05-18T12:29:25.134429+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/I37HCE4S72VJFWXK6I2LX7SBIK","json":"https://pith.science/pith/I37HCE4S72VJFWXK6I2LX7SBIK.json","graph_json":"https://pith.science/api/pith-number/I37HCE4S72VJFWXK6I2LX7SBIK/graph.json","events_json":"https://pith.science/api/pith-number/I37HCE4S72VJFWXK6I2LX7SBIK/events.json","paper":"https://pith.science/paper/I37HCE4S"},"agent_actions":{"view_html":"https://pith.science/pith/I37HCE4S72VJFWXK6I2LX7SBIK","download_json":"https://pith.science/pith/I37HCE4S72VJFWXK6I2LX7SBIK.json","view_paper":"https://pith.science/paper/I37HCE4S","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1508.02930&json=true","fetch_graph":"https://pith.science/api/pith-number/I37HCE4S72VJFWXK6I2LX7SBIK/graph.json","fetch_events":"https://pith.science/api/pith-number/I37HCE4S72VJFWXK6I2LX7SBIK/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/I37HCE4S72VJFWXK6I2LX7SBIK/action/timestamp_anchor","attest_storage":"https://pith.science/pith/I37HCE4S72VJFWXK6I2LX7SBIK/action/storage_attestation","attest_author":"https://pith.science/pith/I37HCE4S72VJFWXK6I2LX7SBIK/action/author_attestation","sign_citation":"https://pith.science/pith/I37HCE4S72VJFWXK6I2LX7SBIK/action/citation_signature","submit_replication":"https://pith.science/pith/I37HCE4S72VJFWXK6I2LX7SBIK/action/replication_record"}},"created_at":"2026-05-18T01:35:23.410776+00:00","updated_at":"2026-05-18T01:35:23.410776+00:00"}