{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2011:I3ZORHMVEH42DEC3MLNOLUQQF5","short_pith_number":"pith:I3ZORHMV","canonical_record":{"source":{"id":"1112.3276","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-12-14T17:02:57Z","cross_cats_sorted":["cond-mat.stat-mech","q-bio.BM"],"title_canon_sha256":"86eb466330f58191f8fbbbdcd88de419641bd142a6897421197ab2ebc5e9c0de","abstract_canon_sha256":"2d278f7b7cad4db8c1c6ff3362179f3cf7ee3ccad8c61d033f1cf21aecc66301"},"schema_version":"1.0"},"canonical_sha256":"46f2e89d9521f9a1905b62dae5d2102f6b7622aeb6e1d2d10d66fb4f4f6b3665","source":{"kind":"arxiv","id":"1112.3276","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1112.3276","created_at":"2026-05-18T03:16:17Z"},{"alias_kind":"arxiv_version","alias_value":"1112.3276v3","created_at":"2026-05-18T03:16:17Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1112.3276","created_at":"2026-05-18T03:16:17Z"},{"alias_kind":"pith_short_12","alias_value":"I3ZORHMVEH42","created_at":"2026-05-18T12:26:30Z"},{"alias_kind":"pith_short_16","alias_value":"I3ZORHMVEH42DEC3","created_at":"2026-05-18T12:26:30Z"},{"alias_kind":"pith_short_8","alias_value":"I3ZORHMV","created_at":"2026-05-18T12:26:30Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2011:I3ZORHMVEH42DEC3MLNOLUQQF5","target":"record","payload":{"canonical_record":{"source":{"id":"1112.3276","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-12-14T17:02:57Z","cross_cats_sorted":["cond-mat.stat-mech","q-bio.BM"],"title_canon_sha256":"86eb466330f58191f8fbbbdcd88de419641bd142a6897421197ab2ebc5e9c0de","abstract_canon_sha256":"2d278f7b7cad4db8c1c6ff3362179f3cf7ee3ccad8c61d033f1cf21aecc66301"},"schema_version":"1.0"},"canonical_sha256":"46f2e89d9521f9a1905b62dae5d2102f6b7622aeb6e1d2d10d66fb4f4f6b3665","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T03:16:17.703701Z","signature_b64":"+UMllPTKX/3GSAf9Kc+C5I1lmjbLTIcwvxWqpUywkC80TrkjBnhHkh7TQ+5mnNZD5NRsrNlE/WSSZSbCDe4oBA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"46f2e89d9521f9a1905b62dae5d2102f6b7622aeb6e1d2d10d66fb4f4f6b3665","last_reissued_at":"2026-05-18T03:16:17.703251Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T03:16:17.703251Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1112.3276","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:16:17Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"fuh66QeT7w/wNSoyC3KdCZ17kOs03oxd8wiHnCRoCwS5MpzITFRb/j5cZJStAsHtvKNZD0cszwQF2GJarbG+BQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-23T21:47:08.282097Z"},"content_sha256":"0335f322a5a4f3a659d4dfb9dca798e76b1da456001b792ff98b4425ae92810e","schema_version":"1.0","event_id":"sha256:0335f322a5a4f3a659d4dfb9dca798e76b1da456001b792ff98b4425ae92810e"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2011:I3ZORHMVEH42DEC3MLNOLUQQF5","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Error correction during DNA replication","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.stat-mech","q-bio.BM"],"primary_cat":"physics.bio-ph","authors_text":"Ajeet K. Sharma, Debashish Chowdhury","submitted_at":"2011-12-14T17:02:57Z","abstract_excerpt":"DNA polymerase (DNAP) is a dual-purpose enzyme that plays two opposite roles in two different situations during DNA replication. It plays its normal role as a {\\it polymerase} catalyzing the elongation of a new DNA molecule by adding a monomer. However, it can switch to the role of an {\\it exonuclease} and shorten the same DNA by cleavage of the last incorporated monomer from the nascent DNA. Just as misincorporated nucleotides can escape exonuclease causing replication error, correct nucleotide may get sacrificed unnecessarily by erroneous cleavage. The interplay of polymerase and exonuclease"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1112.3276","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T03:16:17Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"BBtjGbDixCQ80CMMO1XHTDAOiO67N3RE36BJdTub4zYMBnSAropAebiuw7wIBiaw8lBWB0saL1NWPXZfOlJSAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-23T21:47:08.282932Z"},"content_sha256":"b17f6a3bfc805c631efcfc0eca4001e8a03188669759cec48a6a23900d12834a","schema_version":"1.0","event_id":"sha256:b17f6a3bfc805c631efcfc0eca4001e8a03188669759cec48a6a23900d12834a"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/I3ZORHMVEH42DEC3MLNOLUQQF5/bundle.json","state_url":"https://pith.science/pith/I3ZORHMVEH42DEC3MLNOLUQQF5/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/I3ZORHMVEH42DEC3MLNOLUQQF5/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-23T21:47:08Z","links":{"resolver":"https://pith.science/pith/I3ZORHMVEH42DEC3MLNOLUQQF5","bundle":"https://pith.science/pith/I3ZORHMVEH42DEC3MLNOLUQQF5/bundle.json","state":"https://pith.science/pith/I3ZORHMVEH42DEC3MLNOLUQQF5/state.json","well_known_bundle":"https://pith.science/.well-known/pith/I3ZORHMVEH42DEC3MLNOLUQQF5/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2011:I3ZORHMVEH42DEC3MLNOLUQQF5","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"2d278f7b7cad4db8c1c6ff3362179f3cf7ee3ccad8c61d033f1cf21aecc66301","cross_cats_sorted":["cond-mat.stat-mech","q-bio.BM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-12-14T17:02:57Z","title_canon_sha256":"86eb466330f58191f8fbbbdcd88de419641bd142a6897421197ab2ebc5e9c0de"},"schema_version":"1.0","source":{"id":"1112.3276","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1112.3276","created_at":"2026-05-18T03:16:17Z"},{"alias_kind":"arxiv_version","alias_value":"1112.3276v3","created_at":"2026-05-18T03:16:17Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1112.3276","created_at":"2026-05-18T03:16:17Z"},{"alias_kind":"pith_short_12","alias_value":"I3ZORHMVEH42","created_at":"2026-05-18T12:26:30Z"},{"alias_kind":"pith_short_16","alias_value":"I3ZORHMVEH42DEC3","created_at":"2026-05-18T12:26:30Z"},{"alias_kind":"pith_short_8","alias_value":"I3ZORHMV","created_at":"2026-05-18T12:26:30Z"}],"graph_snapshots":[{"event_id":"sha256:b17f6a3bfc805c631efcfc0eca4001e8a03188669759cec48a6a23900d12834a","target":"graph","created_at":"2026-05-18T03:16:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"DNA polymerase (DNAP) is a dual-purpose enzyme that plays two opposite roles in two different situations during DNA replication. It plays its normal role as a {\\it polymerase} catalyzing the elongation of a new DNA molecule by adding a monomer. However, it can switch to the role of an {\\it exonuclease} and shorten the same DNA by cleavage of the last incorporated monomer from the nascent DNA. Just as misincorporated nucleotides can escape exonuclease causing replication error, correct nucleotide may get sacrificed unnecessarily by erroneous cleavage. The interplay of polymerase and exonuclease","authors_text":"Ajeet K. Sharma, Debashish Chowdhury","cross_cats":["cond-mat.stat-mech","q-bio.BM"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-12-14T17:02:57Z","title":"Error correction during DNA replication"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1112.3276","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:0335f322a5a4f3a659d4dfb9dca798e76b1da456001b792ff98b4425ae92810e","target":"record","created_at":"2026-05-18T03:16:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"2d278f7b7cad4db8c1c6ff3362179f3cf7ee3ccad8c61d033f1cf21aecc66301","cross_cats_sorted":["cond-mat.stat-mech","q-bio.BM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2011-12-14T17:02:57Z","title_canon_sha256":"86eb466330f58191f8fbbbdcd88de419641bd142a6897421197ab2ebc5e9c0de"},"schema_version":"1.0","source":{"id":"1112.3276","kind":"arxiv","version":3}},"canonical_sha256":"46f2e89d9521f9a1905b62dae5d2102f6b7622aeb6e1d2d10d66fb4f4f6b3665","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"46f2e89d9521f9a1905b62dae5d2102f6b7622aeb6e1d2d10d66fb4f4f6b3665","first_computed_at":"2026-05-18T03:16:17.703251Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T03:16:17.703251Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"+UMllPTKX/3GSAf9Kc+C5I1lmjbLTIcwvxWqpUywkC80TrkjBnhHkh7TQ+5mnNZD5NRsrNlE/WSSZSbCDe4oBA==","signature_status":"signed_v1","signed_at":"2026-05-18T03:16:17.703701Z","signed_message":"canonical_sha256_bytes"},"source_id":"1112.3276","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:0335f322a5a4f3a659d4dfb9dca798e76b1da456001b792ff98b4425ae92810e","sha256:b17f6a3bfc805c631efcfc0eca4001e8a03188669759cec48a6a23900d12834a"],"state_sha256":"53062b77ba43326bb1cc46b614addcdd00d497f2b5ca1696bcfe99ce8649bede"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"UPMYaKqu1GnVyhgADTl7LT+P8sBEH6kjoiA2gsd7Rl659IMohU4X3Y2qoXlHOdNoA4clbgXhi1xUOYIASwVTCQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-23T21:47:08.287414Z","bundle_sha256":"63aede24df40656d09a1c785ed3d43410fae63f0ec48b03ec39e3cb431dfdca6"}}