{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:ISO2D4AERFJ3FVNC2NUG37K3A2","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"8f98bd682206bf0abc173dd9aad8697c7e73e160397af10e6c692f5d6738f1b9","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.dis-nn","submitted_at":"2016-05-04T14:25:48Z","title_canon_sha256":"e8071572e595fb1868c71a3b9b4882dcb006c3ecbc553dab711c312ecd5c615a"},"schema_version":"1.0","source":{"id":"1605.01290","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1605.01290","created_at":"2026-05-18T01:08:09Z"},{"alias_kind":"arxiv_version","alias_value":"1605.01290v1","created_at":"2026-05-18T01:08:09Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1605.01290","created_at":"2026-05-18T01:08:09Z"},{"alias_kind":"pith_short_12","alias_value":"ISO2D4AERFJ3","created_at":"2026-05-18T12:30:22Z"},{"alias_kind":"pith_short_16","alias_value":"ISO2D4AERFJ3FVNC","created_at":"2026-05-18T12:30:22Z"},{"alias_kind":"pith_short_8","alias_value":"ISO2D4AE","created_at":"2026-05-18T12:30:22Z"}],"graph_snapshots":[{"event_id":"sha256:3eb46d5eca37d2d0506192047611ffb0a2a156e4978f6b8d268d83c5ec473f79","target":"graph","created_at":"2026-05-18T01:08:09Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"In this work we use belief-propagation techniques to study the equilibrium behaviour of a minimal model for the immune system comprising interacting T and B clones. We investigate the effect of the so-called idiotypic interactions among complementary B clones on the system's activation. Our result shows that B-B interactions increase the system's resilience to noise, making clonal activation more stable, while increasing the cross-talk between different clones. We derive analytically the noise level at which a B clone gets activated, in the absence of cross-talk, and find that this increases w","authors_text":"Alessia Annibale, Alexander Mozeika, Silvia Bartolucci","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.dis-nn","submitted_at":"2016-05-04T14:25:48Z","title":"The role of idiotypic interactions in the adaptive immune system: a belief-propagation approach"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1605.01290","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:5b496c53356b6d43de3a057ea6d3a5fafca479f5bde22bc2dd40ecc43f0c5e80","target":"record","created_at":"2026-05-18T01:08:09Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"8f98bd682206bf0abc173dd9aad8697c7e73e160397af10e6c692f5d6738f1b9","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.dis-nn","submitted_at":"2016-05-04T14:25:48Z","title_canon_sha256":"e8071572e595fb1868c71a3b9b4882dcb006c3ecbc553dab711c312ecd5c615a"},"schema_version":"1.0","source":{"id":"1605.01290","kind":"arxiv","version":1}},"canonical_sha256":"449da1f0048953b2d5a2d3686dfd5b069f287b5d88918947fffd29c5ee576190","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"449da1f0048953b2d5a2d3686dfd5b069f287b5d88918947fffd29c5ee576190","first_computed_at":"2026-05-18T01:08:09.560945Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:08:09.560945Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"QSEKHM+apiI7U4WyQF4IvRVIHPQIkktUmb5Kb9kVEywoyqsztPwL1iCM4LyJBmFP9m1VTMT8NRqtD8VyOimRDQ==","signature_status":"signed_v1","signed_at":"2026-05-18T01:08:09.561471Z","signed_message":"canonical_sha256_bytes"},"source_id":"1605.01290","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:5b496c53356b6d43de3a057ea6d3a5fafca479f5bde22bc2dd40ecc43f0c5e80","sha256:3eb46d5eca37d2d0506192047611ffb0a2a156e4978f6b8d268d83c5ec473f79"],"state_sha256":"d1d103b0cf8438ef55ccba6f68b22fe1eb81b7e213c9ec3309b5eec5cd18ca00"}